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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1969 2
1970 1
1971 1
1972 1
1973 2
1974 2
1975 10
1976 2
1977 5
1978 5
1979 2
1980 3
1981 9
1982 10
1983 9
1984 12
1985 9
1986 15
1987 10
1988 15
1989 9
1990 10
1991 11
1992 10
1993 16
1994 13
1995 7
1996 13
1997 10
1998 10
1999 12
2000 5
2001 14
2002 12
2003 10
2004 15
2005 10
2006 2
2007 12
2008 18
2009 12
2010 15
2011 17
2012 18
2013 19
2014 21
2015 21
2016 30
2017 22
2018 15
2019 16
2020 15
2021 18
2022 19
2023 16
2024 6

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573 results

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Page 1
Neutrophil extracellular traps enriched in oxidized mitochondrial DNA are interferogenic and contribute to lupus-like disease.
Lood C, Blanco LP, Purmalek MM, Carmona-Rivera C, De Ravin SS, Smith CK, Malech HL, Ledbetter JA, Elkon KB, Kaplan MJ. Lood C, et al. Nat Med. 2016 Feb;22(2):146-53. doi: 10.1038/nm.4027. Epub 2016 Jan 18. Nat Med. 2016. PMID: 26779811 Free PMC article.
Mitochondrial ROS are also necessary for spontaneous NETosis of low-density granulocytes from individuals with systemic lupus erythematosus. This was also observed in individuals with chronic granulomatous disease, who lack NADPH oxidase activity but s …
Mitochondrial ROS are also necessary for spontaneous NETosis of low-density granulocytes from individuals with systemic lupus erythematosus. …
Neutrophils: from IBD to the gut microbiota.
Danne C, Skerniskyte J, Marteyn B, Sokol H. Danne C, et al. Nat Rev Gastroenterol Hepatol. 2024 Mar;21(3):184-197. doi: 10.1038/s41575-023-00871-3. Epub 2023 Dec 18. Nat Rev Gastroenterol Hepatol. 2024. PMID: 38110547 Review.
Moreover, severe monogenic diseases involving dysfunctional neutrophils, including chronic granulomatous disease, are characterized by intestinal inflammation that mimics IBD and by alterations in the intestinal microbiota. This observation demonstrate …
Moreover, severe monogenic diseases involving dysfunctional neutrophils, including chronic granulomatous disease, are c …
S100A8/A9 Is a Marker for the Release of Neutrophil Extracellular Traps and Induces Neutrophil Activation.
Sprenkeler EGG, Zandstra J, van Kleef ND, Goetschalckx I, Verstegen B, Aarts CEM, Janssen H, Tool ATJ, van Mierlo G, van Bruggen R, Jongerius I, Kuijpers TW. Sprenkeler EGG, et al. Cells. 2022 Jan 11;11(2):236. doi: 10.3390/cells11020236. Cells. 2022. PMID: 35053354 Free PMC article.
These S100 proteins mainly form heterodimers (S100A8/A9, also known as calprotectin) and this heterocomplex is recognized as a useful biomarker for several inflammatory diseases. We observed that S100A8/A9 is highly present in the cytoplasmic fraction of neutrophils and is …
These S100 proteins mainly form heterodimers (S100A8/A9, also known as calprotectin) and this heterocomplex is recognized as a useful biomar …
Chronic granulomatous disease.
Heyworth PG, Cross AR, Curnutte JT. Heyworth PG, et al. Curr Opin Immunol. 2003 Oct;15(5):578-84. doi: 10.1016/s0952-7915(03)00109-2. Curr Opin Immunol. 2003. PMID: 14499268 Review.
Chronic granulomatous disease (CGD) is a primary immunodeficiency that affects phagocytes of the innate immune system and is characterized by a greatly increased susceptibility to severe bacterial and fungal infections. ...Moreover, recent CGD studies have re …
Chronic granulomatous disease (CGD) is a primary immunodeficiency that affects phagocytes of the innate immune system a …
Intestinal microbiome and metabolome signatures in patients with chronic granulomatous disease.
Chandrasekaran P, Han Y, Zerbe CS, Heller T, DeRavin SS, Kreuzberg SA, Marciano BE, Siu Y, Jones DR, Abraham RS, Stephens MC, Tsou AM, Snapper S, Conlan S, Subramanian P, Quinones M, Grou C, Calderon V, Deming C, Leiding JW, Arnold DE, Logan BR, Griffith LM, Petrovic A, Mousallem TI, Kapoor N, Heimall JR, Barnum JL, Kapadia M, Wright N, Rayes A, Chandra S, Broglie LA, Chellapandian D, Deal CL, Grunebaum E, Lim SS, Mallhi K, Marsh RA, Murguia-Favela L, Parikh S, Touzot F, Cowan MJ, Dvorak CC, Haddad E, Kohn DB, Notarangelo LD, Pai SY, Puck JM, Pulsipher MA, Torgerson TR, Kang EM, Malech HL, Segre JA, Bryant CE, Holland SM, Falcone EL. Chandrasekaran P, et al. J Allergy Clin Immunol. 2023 Dec;152(6):1619-1633.e11. doi: 10.1016/j.jaci.2023.07.022. Epub 2023 Sep 1. J Allergy Clin Immunol. 2023. PMID: 37659505 Free article.
BACKGROUND: Chronic granulomatous disease (CGD) is caused by defects in any 1 of the 6 subunits forming the nicotinamide adenine dinucleotide phosphate oxidase complex 2 (NOX2), leading to severely reduced or absent phagocyte-derived reactive oxygen species p …
BACKGROUND: Chronic granulomatous disease (CGD) is caused by defects in any 1 of the 6 subunits forming the nicotinamid …
Rhinosporidiosis-Factors predicting disease recurrence.
Varghese L, Kurien R, Susheel S, Cherian LM, Rebekah G, Rupa V. Varghese L, et al. Mycoses. 2021 Dec;64(12):1471-1479. doi: 10.1111/myc.13381. Epub 2021 Oct 28. Mycoses. 2021. PMID: 34657340
BACKGROUND: Rhinosporidiosis is a chronic granulomatous disease of the nose caused by Rhinosporidium seeberi. ...
BACKGROUND: Rhinosporidiosis is a chronic granulomatous disease of the nose caused by Rhinosporidium seeberi. ...
NOX2-dependent regulation of inflammation.
Singel KL, Segal BH. Singel KL, et al. Clin Sci (Lond). 2016 Apr 1;130(7):479-90. doi: 10.1042/CS20150660. Clin Sci (Lond). 2016. PMID: 26888560 Free PMC article. Review.
The phagocyte NADPH oxidase (NOX2) is critical for antimicrobial host defence. Chronic granulomatous disease (CGD) is an inherited disorder of NOX2 characterized by severe life-threatening bacterial and fungal infections and by excessive inflammation, includi …
The phagocyte NADPH oxidase (NOX2) is critical for antimicrobial host defence. Chronic granulomatous disease (CGD) is a …
Long-term observational studies of chronic granulomatous disease.
Kanariou M, Spanou K, Tantou S. Kanariou M, et al. Curr Opin Hematol. 2018 Jan;25(1):7-12. doi: 10.1097/MOH.0000000000000396. Curr Opin Hematol. 2018. PMID: 29135572 Review.
PURPOSE OF REVIEW: Chronic granulomatous disease (CGD) is a primary immunodeficiency, with a defect of phagocytes in killing specific pathogens. ...
PURPOSE OF REVIEW: Chronic granulomatous disease (CGD) is a primary immunodeficiency, with a defect of phagocytes in ki …
Severe hematopoietic stem cell inflammation compromises chronic granulomatous disease gene therapy.
Sobrino S, Magnani A, Semeraro M, Martignetti L, Cortal A, Denis A, Couzin C, Picard C, Bustamante J, Magrin E, Joseph L, Roudaut C, Gabrion A, Soheili T, Cordier C, Lortholary O, Lefrere F, Rieux-Laucat F, Casanova JL, Bodard S, Boddaert N, Thrasher AJ, Touzot F, Taque S, Suarez F, Marcais A, Guilloux A, Lagresle-Peyrou C, Galy A, Rausell A, Blanche S, Cavazzana M, Six E. Sobrino S, et al. Cell Rep Med. 2023 Feb 21;4(2):100919. doi: 10.1016/j.xcrm.2023.100919. Epub 2023 Jan 26. Cell Rep Med. 2023. PMID: 36706754 Free PMC article. Clinical Trial.
X-linked chronic granulomatous disease (CGD) is associated with defective phagocytosis, life-threatening infections, and inflammatory complications. ...These two present a profound change in HSC status, a high interferon score, and elevated myeloid pro …
X-linked chronic granulomatous disease (CGD) is associated with defective phagocytosis, life-threatening infections, an …
"Clinical Aspects of Chronic Granulomatous Disease in Upper Egypt".
El-Mokhtar MA, Salama EH, Fahmy EM, Mohamed ME. El-Mokhtar MA, et al. Immunol Invest. 2021 Feb;50(2-3):139-151. doi: 10.1080/08820139.2020.1713144. Epub 2020 Jan 22. Immunol Invest. 2021. PMID: 31965875
Chronic granulomatous disease (CGD) is a rare inherited primary immunodeficiency disorder that affects phagocytes and is characterized by a marked increased susceptibility to severe bacterial and fungal infections. ...We concluded that CGD is common in Upper …
Chronic granulomatous disease (CGD) is a rare inherited primary immunodeficiency disorder that affects phagocytes and i …
573 results