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Clinical, immunological, and genetic features in 938 patients with autoimmune polyendocrinopathy candidiasis ectodermal dystrophy (APECED): a systematic review.
Sharifinejad N, Zaki-Dizaji M, Tebyanian S, Zainaldain H, Jamee M, Rizvi FS, Hosseinzadeh S, Fayyaz F, Hamedifar H, Sabzevari A, Matloubi M, Heropolitańska-Pliszka E, Aghamahdi F, Abolhassani H, Azizi G. Sharifinejad N, et al. Expert Rev Clin Immunol. 2021 Aug;17(8):807-817. doi: 10.1080/1744666X.2021.1925543. Epub 2021 Jun 3. Expert Rev Clin Immunol. 2021. PMID: 33957837
Background: Autoimmune polyendocrinopathy candidiasis ectodermal dystrophy (APECED) is a rare inborn immune error characterized by a triad of chronic mucocutaneous candidiasis (CMC), hypoparathyroidism (HP), and adrenal insufficiency (ADI).Methods: Literature …
Background: Autoimmune polyendocrinopathy candidiasis ectodermal dystrophy (APECED) is a rare inborn immune error characterized by a triad o …
Innate Error Immunities of the Th17 Immune Pathway Associated With Chronic Mucocutaneous Candidiasis: A Systematic Review.
Mirza VS, Zaino ML, Feldman SR. Mirza VS, et al. J Drugs Dermatol. 2023 Dec 1;22(12):1197-1203. doi: 10.36849/JDD.7579. J Drugs Dermatol. 2023. PMID: 38051840
In individuals with compromised immune systems, it can present as chronic mucocutaneous candidiasis (CMC) or systemic infection. CMC often exists in the presence of other infectious phenotypes due to dysfunction of the Th17 immune response. ...
In individuals with compromised immune systems, it can present as chronic mucocutaneous candidiasis (CMC) or systemic i …
Clinical Relevance of Gain- and Loss-of-Function Germline Mutations in STAT1: A Systematic Review.
Zhang W, Chen X, Gao G, Xing S, Zhou L, Tang X, Zhao X, An Y. Zhang W, et al. Front Immunol. 2021 Mar 11;12:654406. doi: 10.3389/fimmu.2021.654406. eCollection 2021. Front Immunol. 2021. PMID: 33777053 Free PMC article.
Results: The search identified 108 publications describing 442 unique patients with STAT1 GOF mutations. The patients documented with chronic mucocutaneous candidiasis (CMC; 410/442), lower respiratory tract infections (210/442), and autoimmune thyroid diseas …
Results: The search identified 108 publications describing 442 unique patients with STAT1 GOF mutations. The patients documented with chr …