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MRP1 polymorphisms associated with citalopram response in patients with major depression.
Lee SH, Lee MS, Lee JH, Kim SW, Kang RH, Choi MJ, Park SJ, Kim SJ, Lee JM, Cole SP, Lee MG. Lee SH, et al. J Clin Psychopharmacol. 2010 Apr;30(2):116-25. doi: 10.1097/JCP.0b013e3181d2ef42. J Clin Psychopharmacol. 2010. PMID: 20520284 Clinical Trial.
Subsequent molecular studies also supported the association between these MRP1 polymorphisms and the citalopram response. Thus, kinetic studies using MRP1-enriched membrane vesicles revealed that citalopram is a substrate of MRP1 (Km = 1.99 microM, Vmax = 137 pmol/m …
Subsequent molecular studies also supported the association between these MRP1 polymorphisms and the citalopram response. Thus …
HTR2A gene-child abuse interaction and association with a history of suicide attempt among Caucasian depressed psychiatric inpatients.
Shinozaki G, Romanowicz M, Mrazek DA, Kung S. Shinozaki G, et al. J Affect Disord. 2013 Sep 25;150(3):1200-3. doi: 10.1016/j.jad.2013.05.028. Epub 2013 Jun 4. J Affect Disord. 2013. PMID: 23759279
Although the A/A genotype of the serotonin receptor SNP (rs7997012) was associated with better citalopram response than the G/G in the STAR*D sample, the effects of this SNP in the moderation of child abuse history on the characteristics of mental illnesses are not …
Although the A/A genotype of the serotonin receptor SNP (rs7997012) was associated with better citalopram response than the G/ …