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Quoted phrase not found in phrase index: "Complement component 4b deficiency"
Page 1
7th International Immunoglobulin Conference: Mechanisms of action.
Basta M, Branch DR. Basta M, et al. Clin Exp Immunol. 2014 Dec;178 Suppl 1(Suppl 1):87-8. doi: 10.1111/cei.12523. Clin Exp Immunol. 2014. PMID: 25546774 Free PMC article.
However, the beneficial effect of IVIg encompasses multiple mechanisms of action. One of these is scavenging of activated complement fragments, such as C3a, C5a, C3b and C4b, by infused Ig molecules. This interaction prevents binding of complement fragments t …
However, the beneficial effect of IVIg encompasses multiple mechanisms of action. One of these is scavenging of activated complement …
Drug-induced immune-complex disease.
Sim E. Sim E. Complement Inflamm. 1989;6(2):119-26. doi: 10.1159/000463084. Complement Inflamm. 1989. PMID: 2524348 Review.
Immune complexes with protein as antigen, such as has been reported to be diagnostic of procainamide-induced SLE, interact more with the C4A isotype of C4 than the C4B isotype. It is shown that hydralazine, isoniazid and penicillamine inhibit the covalent binding of C4 to …
Immune complexes with protein as antigen, such as has been reported to be diagnostic of procainamide-induced SLE, interact more with the C4A …
Coagulation inhibitor substitution during sepsis.
Fourrier F, Jourdain M, Tournois A, Caron C, Goudemand J, Chopin C. Fourrier F, et al. Intensive Care Med. 1995 Nov;21 Suppl 2:S264-8. doi: 10.1007/BF01740765. Intensive Care Med. 1995. PMID: 8636534 Review.
Activation of the contact system induces activation of the classical complement pathway with generation of anaphylatoxins, of the kinins pathway and of fibrinolysis. ...Protein C is activated by thrombomodulin and, with its cofactor protein S, inhibits factors Va and VIIIa …
Activation of the contact system induces activation of the classical complement pathway with generation of anaphylatoxins, of the kin …
A case report of complement C4B deficiency in a patient with steroid and IVIG-refractory anti-NMDA receptor encephalitis.
Chua GT, Zhou D, Ho ACC, Chan SHS, Yu CY, Lau YL. Chua GT, et al. BMC Neurol. 2020 Sep 8;20(1):339. doi: 10.1186/s12883-020-01906-x. BMC Neurol. 2020. PMID: 32900365 Free PMC article.
BACKGROUND: Complement C4A or C4B deficiency has never been reported in autoantibody-associated encephalitides patient. ...Genetic analysis revealed that the index patient has homozygous deficiency in complement C4B and he carries one non …
BACKGROUND: Complement C4A or C4B deficiency has never been reported in autoantibody-associated encephalitides patient. …
Complement component 4 variations may influence psychopathology risk in patients with congenital adrenal hyperplasia due to 21-hydroxylase deficiency.
Lao Q, Jardin MD, Jayakrishnan R, Ernst M, Merke DP. Lao Q, et al. Hum Genet. 2018 Dec;137(11-12):955-960. doi: 10.1007/s00439-018-1959-z. Epub 2018 Nov 21. Hum Genet. 2018. PMID: 30465166 Free PMC article.
CYP21A2 lies within the major histocompatibility complex in an area of the genome highly susceptible to genetic variation. Alterations in the neighboring complement component 4 isotypes C4A and C4B have been associated with psychiatric and autoimmune disease. …
CYP21A2 lies within the major histocompatibility complex in an area of the genome highly susceptible to genetic variation. Alterations in th …
Characteristics of the complement system gene expression deficiency in patients with symptomatic pulmonary embolism.
Lv W, Wang L, Duan Q, Gong Z, Yang F, Song H, Song Y. Lv W, et al. Thromb Res. 2013 Jul;132(1):e54-7. doi: 10.1016/j.thromres.2013.04.027. Epub 2013 May 30. Thromb Res. 2013. PMID: 23726092 Free PMC article. Clinical Trial.
Human cDNA microarray analysis was used to detect the gene expression difference of the complement system between the two groups. RESULTS: 1). Expression of twenty-one genes encoding complement components was detected. ...CONCLUSIONS: In PE patients, the mRNA expres …
Human cDNA microarray analysis was used to detect the gene expression difference of the complement system between the two groups. RES …
Safety and Immunogenicity of ChAd63/MVA Pfs25-IMX313 in a Phase I First-in-Human Trial.
de Graaf H, Payne RO, Taylor I, Miura K, Long CA, Elias SC, Zaric M, Minassian AM, Silk SE, Li L, Poulton ID, Baker M, Draper SJ, Gbesemete D, Brendish NJ, Martins F, Marini A, Mekhaiel D, Edwards NJ, Roberts R, Vekemans J, Moyle S, Faust SN, Berrie E, Lawrie AM, Hill F, Hill AVS, Biswas S. de Graaf H, et al. Front Immunol. 2021 Jul 14;12:694759. doi: 10.3389/fimmu.2021.694759. eCollection 2021. Front Immunol. 2021. PMID: 34335606 Free PMC article. Clinical Trial.
The Plasmodium falciparum Pfs25 protein (Pfs25) is the most clinically advanced candidate sexual-stage antigen. IMX313, a complement inhibitor C4b-binding protein that forms heptamers with the antigen fused to it, improve antibody responses. This is the first time t …
The Plasmodium falciparum Pfs25 protein (Pfs25) is the most clinically advanced candidate sexual-stage antigen. IMX313, a complement …
Complement 4 locus II gene deletion and DQA1*0301 gene: genetic risk factors for IgA nephropathy and Henoch-Schonlein nephritis.
Jin DK, Kohsaka T, Koo JW, Ha IS, Cheong HI, Choi Y. Jin DK, et al. Nephron. 1996;73(3):390-5. doi: 10.1159/000189098. Nephron. 1996. PMID: 8832595 Clinical Trial.
There have been several reports suggesting that the deficiency of complement 4 (C4) and/or deletion of C4 genes are the genetic risk factors in patients with IgA nephropathy (IgAN) and Henoch-Schonlein nephritis (HSN). ...Our results showed that locus II deletion of …
There have been several reports suggesting that the deficiency of complement 4 (C4) and/or deletion of C4 genes are the geneti …
The combination of complement deficiency and cigarette smoking as risk factor for cutaneous lupus erythematosus in men; a focus on combined C2/C4 deficiency.
Boeckler P, Milea M, Meyer A, Uring-Lambert B, Heid E, Hauptmann G, Cribier B, Lipsker D. Boeckler P, et al. Br J Dermatol. 2005 Feb;152(2):265-70. doi: 10.1111/j.1365-2133.2004.06308.x. Br J Dermatol. 2005. PMID: 15727637
Among environmental factors, it was postulated that cigarette smoking might intervene in the pathogenesis of LE. OBJECTIVES: To describe the clinical and biological features of patients with CLE and a complement deficiency. ...Among 32 screened patients, 24 p …
Among environmental factors, it was postulated that cigarette smoking might intervene in the pathogenesis of LE. OBJECTIVES: To describe the …
Shotgun proteomic analysis reveals proteome alterations in HDL of patients with cholesteryl ester transfer protein deficiency.
Okada T, Ohama T, Takafuji K, Kanno K, Matsuda H, Sairyo M, Zhu Y, Saga A, Kobayashi T, Masuda D, Koseki M, Nishida M, Sakata Y, Yamashita S. Okada T, et al. J Clin Lipidol. 2019 Mar-Apr;13(2):317-325. doi: 10.1016/j.jacl.2019.01.002. Epub 2019 Jan 11. J Clin Lipidol. 2019. PMID: 30745272
OBJECTIVE: This study aimed to investigate the protein composition of HDL particles in patients with CETP-D. METHODS: Eight patients with complete deficiency of CETP and 8 normolipidemic healthy subjects were enrolled. ...Spectral counts of apolipoprotein (apo) E were incr …
OBJECTIVE: This study aimed to investigate the protein composition of HDL particles in patients with CETP-D. METHODS: Eight patients with co …
30 results