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209 results

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Quoted phrase not found in phrase index: "Congenital absence of germinal epithelium of testes"
Page 1
Identification and verification of potential biomarkers in sertoli cell-only syndrome via bioinformatics analysis.
Jiang Y, Yang X, Li L, Lv X, Wang R, Zhang H, Liu R. Jiang Y, et al. Sci Rep. 2023 Jul 27;13(1):12164. doi: 10.1038/s41598-023-38947-4. Sci Rep. 2023. PMID: 37500704 Free PMC article.
Sertoli cell-only syndrome (SCOS), a severe testicular spermatogenic failure, is characterized by total absence of male germ cells. ...The expression levels of the hub genes were significantly decreased in patients with SCOS compared to that in …
Sertoli cell-only syndrome (SCOS), a severe testicular spermatogenic failure, is characterized by total absen …
Joint analysis of m(6)A and mRNA expression profiles in the testes of idiopathic nonobstructive azoospermia patients.
Tang Q, Wu W, Lu Y, Zhou Y, Wu W, Li J, Pan L, Ling X, Pan F. Tang Q, et al. Front Endocrinol (Lausanne). 2022 Dec 15;13:1063929. doi: 10.3389/fendo.2022.1063929. eCollection 2022. Front Endocrinol (Lausanne). 2022. PMID: 36589848 Free PMC article.
OBJECTIVE: To determine the differential expression of mRNA and m(6)A methylation status in the testes of iNOA patients. METHODS: Testes tissues from diagnosed iNOA and controlled obstructive azoospermia (OA) patients were collected and grouped according to the hist …
OBJECTIVE: To determine the differential expression of mRNA and m(6)A methylation status in the testes of iNOA patients. METHODS: …
Possible fetal determinants of male infertility.
Juul A, Almstrup K, Andersson AM, Jensen TK, Jørgensen N, Main KM, Rajpert-De Meyts E, Toppari J, Skakkebæk NE. Juul A, et al. Nat Rev Endocrinol. 2014 Sep;10(9):553-62. doi: 10.1038/nrendo.2014.97. Epub 2014 Jun 17. Nat Rev Endocrinol. 2014. PMID: 24935122 Review.
The evidence is derived not only from large epidemiological studies that show birth-cohort effects with regard to testicular cancer, levels of testosterone and semen quality, but also from histopathological observations. Many infertile men have histological signs of testic …
The evidence is derived not only from large epidemiological studies that show birth-cohort effects with regard to testicular cancer, levels …
Predictors of surgical sperm retrieval in non-obstructive azoospermia: summary of current literature.
Arshad MA, Majzoub A, Esteves SC. Arshad MA, et al. Int Urol Nephrol. 2020 Nov;52(11):2015-2038. doi: 10.1007/s11255-020-02529-4. Epub 2020 Jun 9. Int Urol Nephrol. 2020. PMID: 32519242 Review.
Given the variability in clinical presentation, the potential role of factors that can predict the likelihood of successful testicular SR needs to be clarified. ...Clinical and laboratory factors, as well as adjuvant therapies and surgical retrieval methods, were the facto …
Given the variability in clinical presentation, the potential role of factors that can predict the likelihood of successful testicula …
Aberrant Gene Expression Profiling in Men With Sertoli Cell-Only Syndrome.
Chen T, Wang Y, Tian L, Guo X, Xia J, Wang Z, Song N. Chen T, et al. Front Immunol. 2022 Jun 27;13:821010. doi: 10.3389/fimmu.2022.821010. eCollection 2022. Front Immunol. 2022. PMID: 35833143 Free PMC article.
Sertoli cell-only syndrome (SCOS) is the most severe and common pathological type of non-obstructive azoospermia. ...Based on the downregulated genes, transcription factors (TFs) and kinases within the upstream regulatory network were predicted. …
Sertoli cell-only syndrome (SCOS) is the most severe and common pathological type of non-obstructive azoospermia …
Features of gonadal dysgenesis and Leydig cell impairment in testes with Sertoli cell-only syndrome.
Adamczewska D, Slowikowska-Hilczer J, Marchlewska K, Walczak-Jedrzejowska R. Adamczewska D, et al. Folia Histochem Cytobiol. 2020;58(2):73-82. doi: 10.5603/FHC.a2020.0008. Epub 2020 Jun 3. Folia Histochem Cytobiol. 2020. PMID: 32490535 Free article.
INTRODUCTION: There is evidence that disturbed spermatogenesis is associated with impaired Leydig cell function and that it may be the result of testicular dysgenesis during fetal/infant development. Sertoli cell-only syndrome (SCOS) is defined by comp …
INTRODUCTION: There is evidence that disturbed spermatogenesis is associated with impaired Leydig cell function and that it may be the resul …
Azoospermia factor c microdeletions and outcomes of assisted reproductive technology: a systematic review and meta-analysis.
Colaco S, Modi D. Colaco S, et al. Fertil Steril. 2024 Jan;121(1):63-71. doi: 10.1016/j.fertnstert.2023.10.029. Epub 2023 Nov 3. Fertil Steril. 2024. PMID: 37923163 Review.
A significantly lower fertilization rate (OR = 0.61, 95% CI [0.50, 0.74]), clinical pregnancy rate (OR = 0.61, 95% CI [0.42, 0.89]), and live birth rate (OR = 0.54, 95% CI [0.40, 0.72]) were observed in men with AZFc deletions compared with men without deletions. ...
A significantly lower fertilization rate (OR = 0.61, 95% CI [0.50, 0.74]), clinical pregnancy rate (OR = 0.61, 95% CI [0.42, 0.89]), and liv …
Immunohistochemical measurement and expression of Mcl-1 in infertile testes.
Hegazy R, Hegazy A, Ammar M, Salem E. Hegazy R, et al. Front Med. 2015 Sep;9(3):361-7. doi: 10.1007/s11684-015-0395-x. Epub 2015 Jun 17. Front Med. 2015. PMID: 26085468
Forty-five cases of maturation arrest (25 at spermatids and 20 at the spermatocytes), 31 cases of hypospermatogenesis (20 moderate and 11 severe), 5 cases of Sertoli cell-only syndrome, 2 cases of basement membrane hyalinization, and 1 case of tubular …
Forty-five cases of maturation arrest (25 at spermatids and 20 at the spermatocytes), 31 cases of hypospermatogenesis (20 moderate and 11 se …
Developmental expression and function of DKKL1/Dkkl1 in humans and mice.
Yan Q, Wu X, Chen C, Diao R, Lai Y, Huang J, Chen J, Yu Z, Gui Y, Tang A, Cai Z. Yan Q, et al. Reprod Biol Endocrinol. 2012 Jul 21;10:51. doi: 10.1186/1477-7827-10-51. Reprod Biol Endocrinol. 2012. PMID: 22817830 Free PMC article.
Examination of the tissue distribution of Dkkl1 demonstrated that while Dkkl1 mRNA was abundantly expressed in testes, little to no expression of Dkkl1 was observed in the epididymis or other tissues. ...Additionally, immunohistochemical staining showed that the DKK …
Examination of the tissue distribution of Dkkl1 demonstrated that while Dkkl1 mRNA was abundantly expressed in testes, little to no e …
Testis cell pyroptosis mediated by CASP1 and CASP4: possible sertoli cell-only syndrome pathogenesis.
Liu W, Li X, Ma Q, Zhu Y, Zhao W, Yang Y, Xiao W, Huang D, Cai F, Chan DYL, Zhao S, Chu Q. Liu W, et al. Reprod Biol Endocrinol. 2023 Jun 9;21(1):53. doi: 10.1186/s12958-023-01101-w. Reprod Biol Endocrinol. 2023. PMID: 37296437 Free PMC article.
BACKGROUND: Sertoli cell-only syndrome (SCOS) is the most serious pathological type of non-obstructive azoospermia. ...CONCLUSIONS: For the first time, we found that cell pyroptosis-related genes and key markers were significantly increased in the t …
BACKGROUND: Sertoli cell-only syndrome (SCOS) is the most serious pathological type of non-obstructive azoosperm …
209 results