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2005 1
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Page 1
Congenital Fibrinogen Deficiency in India and Role of Human Fibrinogen Concentrate.
John MJ, Byreddy P, Modak K, Makkar M. John MJ, et al. Acta Haematol. 2021;144(6):595-602. doi: 10.1159/000516339. Epub 2021 Jun 4. Acta Haematol. 2021. PMID: 34091452 Free article. Review.
The hemostatic efficacy and safety of human fibrinogen concentrate in congenital fibrinogen deficiency is well established in the literature. We review the prevalence of congenital fibrinogen deficiency in India and the current role of hu …
The hemostatic efficacy and safety of human fibrinogen concentrate in congenital fibrinogen deficiency is well establis …
Epidemiology and treatment of congenital fibrinogen deficiency.
Peyvandi F. Peyvandi F. Thromb Res. 2012 Dec;130 Suppl 2:S7-11. doi: 10.1016/S0049-3848(13)70004-5. Thromb Res. 2012. PMID: 23439004
Congenital fibrinogen deficiency is a rare bleeding disorder, affecting either the quantity (afibrinogenemia, hypofibrinogenemia) or quality (dysfibrinogenemia) of circulating fibrinogen. ...Fibrinogen replacement therapy is effective in treating bleeding epi
Congenital fibrinogen deficiency is a rare bleeding disorder, affecting either the quantity (afibrinogenemia, hypofibri
Congenital fibrinogen disorders: a retrospective clinical and genetic analysis of the Prospective Rare Bleeding Disorders Database.
Mohsenian S, Palla R, Menegatti M, Cairo A, Lecchi A, Casini A, Neerman-Arbez M, Asselta R, Scardo S, Siboni SM, Blatny J, Zapletal O, Schved JF, Giansily-Blaizot M, Halimeh S, Daoud MA, Platokouki H, Pergantou H, Schutgens REG, Van Haaften-Spoor M, Brons P, Laros-van Gorkom B, Van Pinxten E, Borhany M, Fatima N, Mikovic D, Saracevic M, Özdemir GN, Ay Y, Makris M, Lockley C, Mumford A, Harvey A, Austin S, Shapiro A, Williamson A, McGuinn C, Goldberg I, De Moerloose P, Peyvandi F. Mohsenian S, et al. Blood Adv. 2024 Mar 26;8(6):1392-1404. doi: 10.1182/bloodadvances.2023012186. Blood Adv. 2024. PMID: 38286442 Free PMC article.
Congenital fibrinogen deficiency (CFD) is a rare bleeding disorder caused by mutations in FGA, FGB, and FGG. ...
Congenital fibrinogen deficiency (CFD) is a rare bleeding disorder caused by mutations in FGA, FGB, and FGG. ...
Fibrinogen concentrate for treatment of bleeding and surgical prophylaxis in congenital fibrinogen deficiency patients.
Lissitchkov T, Madan B, Djambas Khayat C, Zozulya N, Ross C, Karimi M, Kavakli K, De Angulo GR, Almomen A, Subramanian K, D'Souza F, Viswabandya A, Hoorfar H, Schwartz BA, Solomon C, Knaub S, Peyvandi F. Lissitchkov T, et al. J Thromb Haemost. 2020 Apr;18(4):815-824. doi: 10.1111/jth.14727. Epub 2020 Jan 21. J Thromb Haemost. 2020. PMID: 31885190 Free PMC article.
BACKGROUND: Congenital fibrinogen deficiency is an ultra-rare disorder in which patients can experience severe and/or frequent bleeding episodes (BEs). ...
BACKGROUND: Congenital fibrinogen deficiency is an ultra-rare disorder in which patients can experience severe and/or f …
Efficacy and safety of fibrinogen concentrate for perioperative prophylaxis of bleeding in adult, adolescent, and pediatric patients with congenital fibrinogen deficiency: FORMA-02 and FORMA-04 clinical trials.
Khayat CD, Lohade S, Zekavat OR, Kruzhkova I, Solomon C, Peyvandi F. Khayat CD, et al. Transfusion. 2022 Sep;62(9):1871-1881. doi: 10.1111/trf.17029. Epub 2022 Aug 6. Transfusion. 2022. PMID: 35932202 Free PMC article. Clinical Trial.
BACKGROUND: Congenital fibrinogen deficiency (CFD) is a rare coagulation disorder placing patients at increased bleeding risk. ...
BACKGROUND: Congenital fibrinogen deficiency (CFD) is a rare coagulation disorder placing patients at increased bleedin …
Efficacy and safety of a new human fibrinogen concentrate in patients with congenital fibrinogen deficiency: an interim analysis of a Phase III trial.
Lissitchkov T, Madan B, Djambas Khayat C, Zozulya N, Ross C, Karimi M, Kavakli K, De Angulo GR, Almomen A, Schwartz BA, Solomon C, Knaub S, Peyvandi F. Lissitchkov T, et al. Transfusion. 2018 Feb;58(2):413-422. doi: 10.1111/trf.14421. Epub 2017 Nov 30. Transfusion. 2018. PMID: 29194665 Free article. Clinical Trial.
BACKGROUND: Fibrinogen concentrate is the preferred choice for fibrinogen replacement in congenital fibrinogen deficiency. This study investigated hemostatic efficacy of a new plasma-derived, double virus-inactivated (using two dedicated virus inactivation/el …
BACKGROUND: Fibrinogen concentrate is the preferred choice for fibrinogen replacement in congenital fibrinogen deficiency
Clinical pharmacology, efficacy and safety study of a triple-secured fibrinogen concentrate in adults and adolescent patients with congenital fibrinogen deficiency.
Djambas Khayat C, El Khorassani M, Lambert T, Gay V, Barthez-Toullec M, Lamazure J, Bellon A, Henriet C, Bridey F, Négrier C. Djambas Khayat C, et al. J Thromb Haemost. 2019 Apr;17(4):635-644. doi: 10.1111/jth.14392. Epub 2019 Feb 20. J Thromb Haemost. 2019. PMID: 30661302 Free article. Clinical Trial.
Essentials A novel fibrinogen concentrate was evaluated in patients with congenital fibrinogen deficiency. An open-label, phase 2-3 trial studied pharmacology, efficacy, and safety in patients >6 years. ...
Essentials A novel fibrinogen concentrate was evaluated in patients with congenital fibrinogen deficiency. An open-labe …
Pharmacokinetics and safety of fibrinogen concentrate.
Manco-Johnson MJ, Dimichele D, Castaman G, Fremann S, Knaub S, Kalina U, Peyvandi F, Piseddu G, Mannucci P; FIBRINOGEN CONCENTRATE STUDY GROUP. Manco-Johnson MJ, et al. J Thromb Haemost. 2009 Dec;7(12):2064-9. doi: 10.1111/j.1538-7836.2009.03633.x. Epub 2009 Oct 5. J Thromb Haemost. 2009. PMID: 19804533 Free article. Clinical Trial.
BACKGROUND: Although fibrinogen concentrate has been available for the treatment of congenital fibrinogen deficiency for years, knowledge of its pharmacokinetics comes from only two small studies. ...
BACKGROUND: Although fibrinogen concentrate has been available for the treatment of congenital fibrinogen deficiency fo …
Efficacy and tolerability of a pasteurised human fibrinogen concentrate in patients with congenital fibrinogen deficiency.
Kreuz W, Meili E, Peter-Salonen K, Haertel S, Devay J, Krzensk U, Egbring R. Kreuz W, et al. Transfus Apher Sci. 2005 Jun;32(3):247-53. doi: 10.1016/j.transci.2004.08.003. Transfus Apher Sci. 2005. PMID: 15919240
The efficacy and tolerability of a pasteurised human fibrinogen concentrate were assessed in an open, multi-centre, non-controlled retrospective study in patients with congenital fibrinogen deficiency. Haemostatic efficacy was assessed by laboratory investiga …
The efficacy and tolerability of a pasteurised human fibrinogen concentrate were assessed in an open, multi-centre, non-controlled retrospec …
11 results