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2010 1
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2015 2
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41 results

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Page 1
Does the Clinical Presentation of Secondary Osteosarcoma in Patients Who Survive Retinoblastoma Differ From That of Conventional Osteosarcoma and How Do We Detect Them?
Kim Y, Park JW, Cho HS, Jang WY, Han I, Kim HS. Kim Y, et al. Clin Orthop Relat Res. 2023 Nov 1;481(11):2154-2163. doi: 10.1097/CORR.0000000000002667. Epub 2023 May 5. Clin Orthop Relat Res. 2023. PMID: 37145140 Review.
All patients were treated with the same strategy as that used for primary conventional osteosarcoma, namely neoadjuvant chemotherapy, wide excision, and adjuvant chemotherapy. ...The clinical survivorship of osteosarcoma as a secondary malignancy after retinoblastom …
All patients were treated with the same strategy as that used for primary conventional osteosarcoma, namely neoadjuvant chemot …
Molecular Pathogenesis and Diagnostic, Prognostic and Predictive Molecular Markers in Sarcoma.
Mariño-Enríquez A, Bovée JV. Mariño-Enríquez A, et al. Surg Pathol Clin. 2016 Sep;9(3):457-73. doi: 10.1016/j.path.2016.04.009. Surg Pathol Clin. 2016. PMID: 27523972 Free PMC article. Review.
Molecular studies in sarcoma provide refinements to morphologic classification, and contribute diagnostic information (frequently), prognostic stratification (rarely) and predict therapeutic response (occasionally). Herein, we summarize the major molecular mechanisms under …
Molecular studies in sarcoma provide refinements to morphologic classification, and contribute diagnostic information (frequently), prognost …
Jaw osteosarcoma models in mice: first description.
Bertin H, Guilho R, Brion R, Amiaud J, Battaglia S, Moreau A, Brouchet-Gomez A, Longis J, Piot B, Heymann D, Corre P, Rédini F. Bertin H, et al. J Transl Med. 2019 Feb 27;17(1):56. doi: 10.1186/s12967-019-1807-5. J Transl Med. 2019. PMID: 30813941 Free PMC article.
These models were characterized at the histological and micro-CT imaging levels, as well as in terms of tumor growth and metastatic spread. RESULTS: Homogeneous tumor growth was observed in both the HOS1544 and the MOS-J JOS models by injection of 0.25 10(6) and 0.50 10(6) …
These models were characterized at the histological and micro-CT imaging levels, as well as in terms of tumor growth and metastatic spread. …
Response to neoadjuvant chemotherapy and survival of children and adolescents with high-grade osteosarcoma treated based on the EURAMOS-1 protocol.
Suárez-Mattos A, Arroyave F, Infante AM, Narváez C, Soto C, Gómez L, Amaya-Nieto J. Suárez-Mattos A, et al. Bol Med Hosp Infant Mex. 2022;79(1):17-25. doi: 10.24875/BMHIM.21000087. Bol Med Hosp Infant Mex. 2022. PMID: 35086129 Free article. English.

This study aimed to evaluate the histologic response to neoadjuvant chemotherapy and overall and event-free survival rates in patients < 21 years of age with a diagnosis of conventional osteosarcoma. METHODS: We conducted an analytical and observational st

This study aimed to evaluate the histologic response to neoadjuvant chemotherapy and overall and event-free survival rates in patients < …
Investigation of crucial genes and microRNAs in conventional osteosarcoma using gene expression profiling analysis.
Peng C, Yang Q, Wei B, Yuan B, Liu Y, Li Y, Gu D, Yin G, Wang B, Xu D, Zhang X, Kong D. Peng C, et al. Mol Med Rep. 2017 Nov;16(5):7617-7624. doi: 10.3892/mmr.2017.7506. Epub 2017 Sep 18. Mol Med Rep. 2017. PMID: 28944822
The present study aimed to screen potential genes associated with conventional osteosarcoma (OS) and obtain further information on the pathogenesis of this disease. ...Additionally, the potential microRNAs (miRNAs) for the upregulated DEGs in the most significant pa …
The present study aimed to screen potential genes associated with conventional osteosarcoma (OS) and obtain further informatio …
Gene amplification and tumor grading in parosteal osteosarcoma.
Chen PC, Yen CC, Hung GY, Pan CC, Chen WM. Chen PC, et al. J Chin Med Assoc. 2019 Dec;82(12):889-894. doi: 10.1097/JCMA.0000000000000211. J Chin Med Assoc. 2019. PMID: 31634336
All POS showed increased expression of both MDM2 and CDK4 proteins, but not those from conventional osteosarcoma. Except some tumors were non-informative (poor DNA quality), the rest of POS had a marked increase of MDM2 and CDK4 genes copies by MQPCR, and confirmed …
All POS showed increased expression of both MDM2 and CDK4 proteins, but not those from conventional osteosarcoma. Except some …
Extraskeletal osteosarcoma in Norway, between 1975 and 2009, and a brief review of the literature.
Berner K, Bjerkehagen B, Bruland ØS, Berner A. Berner K, et al. Anticancer Res. 2015 Apr;35(4):2129-40. Anticancer Res. 2015. PMID: 25862869
Primary metastatic disease, elevated tumour size and elevated serum alkaline phosphatase, serum lactate dehydrogenase and Ki67, respectively, all predicted poor outcome. CONCLUSION: The relatively poor prognosis of ESOS may relate to both primary chemotherapy resistance an …
Primary metastatic disease, elevated tumour size and elevated serum alkaline phosphatase, serum lactate dehydrogenase and Ki67, respectively …
Large and round tumor nuclei in osteosarcoma: good clinical outcome.
de Andrea CE, Petrilli AS, Jesus-Garcia R, Bleggi-Torres LF, Alves MT. de Andrea CE, et al. Int J Clin Exp Pathol. 2011 Jan 30;4(2):169-74. Int J Clin Exp Pathol. 2011. PMID: 21326812 Free PMC article.
Distinct histological features are distinguishable based on the morphology of the tumor. Differences in nuclei size and shape are often observed in osteosarcoma reflecting its broad histopathological heterogeneity. This study explores the relevance of two nuclear parameter …
Distinct histological features are distinguishable based on the morphology of the tumor. Differences in nuclei size and shape are often o
Correlation between ERK1 and STAT3 expression and chemoresistance in patients with conventional osteosarcoma.
Salas S, Jiguet-Jiglaire C, Campion L, Bartoli C, Frassineti F, Deville JL, Maues De Paula A, Forest F, Jézéquel P, Gentet JC, Bouvier C. Salas S, et al. BMC Cancer. 2014 Aug 20;14:606. doi: 10.1186/1471-2407-14-606. BMC Cancer. 2014. PMID: 25146150 Free PMC article.
BACKGROUND: The standard therapy regimen of conventional osteosarcoma includes neoadjuvant chemotherapy followed by surgical resection and postoperative chemotherapy. ...CONCLUSIONS: Our results suggest that ERK1 and STAT3 expression are good predictive marke …
BACKGROUND: The standard therapy regimen of conventional osteosarcoma includes neoadjuvant chemotherapy followed by surgical r …
41 results