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28 results

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Page 1
Chordoma.
Ulici V, Hart J. Ulici V, et al. Arch Pathol Lab Med. 2022 Mar 1;146(3):386-395. doi: 10.5858/arpa.2020-0258-RA. Arch Pathol Lab Med. 2022. PMID: 34319396 Free article. Review.
.-: To summarize the clinical and pathologic findings of the various types of chordoma (conventional chordoma, dedifferentiated chordoma, and poorly differentiated chordoma), the differential diagnosis, and recent advances in molecular pathogenesis and therapeutic m …
.-: To summarize the clinical and pathologic findings of the various types of chordoma (conventional chordoma, dedifferentiate …
Notochordal Tumors.
Tirabosco R, O'Donnell P, Flanagan AM. Tirabosco R, et al. Surg Pathol Clin. 2021 Dec;14(4):619-643. doi: 10.1016/j.path.2021.06.006. Epub 2021 Jul 28. Surg Pathol Clin. 2021. PMID: 34742484 Review.
This spectrum encompasses benign entities that are mostly discovered incidentally on imaging, reported as benign notochordal cell tumor, usually not requiring surgical intervention; slowly growing and histologically low-grade tumors referred to as conventional chordoma …
This spectrum encompasses benign entities that are mostly discovered incidentally on imaging, reported as benign notochordal cell tumor, usu …
Squash smear and fine needle aspiration features of conventional chordoma.
Gajdzis P, Klijanienko J, Gajdzis M. Gajdzis P, et al. Cytopathology. 2023 Sep;34(5):503-506. doi: 10.1111/cyt.13225. Epub 2023 Mar 13. Cytopathology. 2023. PMID: 36840426
Proper intraoperative or preoperative diagnosis of this entity is crucial for appropriate surgical management. The most common histopathological subtype is conventional chordoma. Cytological characteristics of this subtype are quite distinctive and the diagnosis can …
Proper intraoperative or preoperative diagnosis of this entity is crucial for appropriate surgical management. The most common histopatholog …
Molecular characteristics of poorly differentiated chordoma.
Shih AR, Chebib I, Deshpande V, Dickson BC, Iafrate AJ, Nielsen GP. Shih AR, et al. Genes Chromosomes Cancer. 2019 Nov;58(11):804-808. doi: 10.1002/gcc.22782. Epub 2019 Jun 13. Genes Chromosomes Cancer. 2019. PMID: 31135077
This study characterizes the molecular features of these tumors in comparison to conventional chordoma. A search of records between 1990 and 2017 at Massachusetts General Hospital identified two patients with sufficient excess tissue for molecular analysis and a thi …
This study characterizes the molecular features of these tumors in comparison to conventional chordoma. A search of records be …
Predict overall survival of spinal conventional chordoma: Development and assessment of a new predictive nomogram.
Lin K, Song K, Wang S, Jiang L, Wang H, Dong J. Lin K, et al. Clin Neurol Neurosurg. 2020 Oct;197:106174. doi: 10.1016/j.clineuro.2020.106174. Epub 2020 Aug 22. Clin Neurol Neurosurg. 2020. PMID: 32889324
OBJECTIVE: To predict the 5-year overall survival (OS) rate in patients with conventional chordoma of the spine PATIENTS AND METHODS: The Surveillance, Epidemiology, and End Results (SEER) Registry was used to identify patients with conventional chordoma …
OBJECTIVE: To predict the 5-year overall survival (OS) rate in patients with conventional chordoma of the spine PATIENTS AND M …
Dedifferentiated Chordoma: Clinicopathologic and Molecular Characteristics With Integrative Analysis.
Hung YP, Diaz-Perez JA, Cote GM, Wejde J, Schwab JH, Nardi V, Chebib IA, Deshpande V, Selig MK, Bredella MA, Rosenberg AE, Nielsen GP. Hung YP, et al. Am J Surg Pathol. 2020 Sep;44(9):1213-1223. doi: 10.1097/PAS.0000000000001501. Am J Surg Pathol. 2020. PMID: 32427623
Dedifferentiated chordoma is a rare chordoma subtype characterized by a high-grade sarcoma juxtaposed to conventional chordoma. We identified a series of dedifferentiated chordomas, reviewed clinicopathologic features, performed next-generation sequencing in select …
Dedifferentiated chordoma is a rare chordoma subtype characterized by a high-grade sarcoma juxtaposed to conventional chordoma …
Differences in stromal component of chordoma are associated with contrast enhancement in MRI and differential gene expression in RNA sequencing.
Park M, Park I, Hong CK, Kim SH, Cha YJ. Park M, et al. Sci Rep. 2022 Oct 3;12(1):16504. doi: 10.1038/s41598-022-20787-3. Sci Rep. 2022. PMID: 36192442 Free PMC article.
Here, we aimed to investigate the histologic, radiologic, and transcriptomic differences in conventional chordoma based on the stromal component. A total of 45 patients diagnosed with conventional chordoma were selected between May 2011 and March 2020 …
Here, we aimed to investigate the histologic, radiologic, and transcriptomic differences in conventional chordoma based on the …
Spinal chordomas dedifferentiated to osteosarcoma: a report of two cases and a literature review.
Kato S, Gasbarrini A, Ghermandi R, Gambarotti M, Bandiera S. Kato S, et al. Eur Spine J. 2016 May;25 Suppl 1:251-6. doi: 10.1007/s00586-016-4557-6. Epub 2016 Apr 6. Eur Spine J. 2016. PMID: 27052403 Review.
METHODS AND RESULTS: In both patients, the diagnosis on the first computed tomography (CT)-guided trocar biopsy of the tumor was a conventional chordoma. The two cases represent dedifferentiated chordomas with a sharp demarcation between the conventional c …
METHODS AND RESULTS: In both patients, the diagnosis on the first computed tomography (CT)-guided trocar biopsy of the tumor was a conven …
Brachyury expression in intracranial SMARCB1-deficient tumors: important points for distinguishing poorly differentiated chordoma from atypical teratoid/rhabdoid tumor.
Kohashi K, Yamamoto H, Yamada Y, Kinoshita I, Oda Y. Kohashi K, et al. Hum Pathol. 2021 Jun;112:1-8. doi: 10.1016/j.humpath.2021.03.001. Epub 2021 Mar 17. Hum Pathol. 2021. PMID: 33741347
Brachyury and cytokeratin immunoexpression status was examined in 42 formalin-fixed paraffin-embedded SMARCB1-deficient tumor specimens (PCh, 6 cases; extra-central nervous system [CNS] MRT, 26 cases; AT/RT, 10 cases) and 25 cases of conventional chordoma (CCh). All …
Brachyury and cytokeratin immunoexpression status was examined in 42 formalin-fixed paraffin-embedded SMARCB1-deficient tumor specimens (PCh …
28 results