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Year Number of Results
1976 1
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2015 4
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2020 3
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Page 1
The pathophysiology of Fuchs' endothelial dystrophy--a review of molecular and cellular insights.
Zhang J, Patel DV. Zhang J, et al. Exp Eye Res. 2015 Jan;130:97-105. doi: 10.1016/j.exer.2014.10.023. Epub 2014 Nov 1. Exp Eye Res. 2015. PMID: 25446318 Review.
Fuchs' endothelial corneal dystrophy (FECD) is the most common corneal endothelial dystrophy and commonly results in loss of vision. ...Many of the microstructural changes occurring in FECD may be observed with IVCM, and these observations corre …
Fuchs' endothelial corneal dystrophy (FECD) is the most common corneal endothelial dystrophy and commonly results in lo …
Emerging treatments for corneal endothelium decompensation - a systematic review.
Cheong N, Chui SW, Poon SHL, Wong HL, Shih KC, Chan YK. Cheong N, et al. Graefes Arch Clin Exp Ophthalmol. 2024 Feb;262(2):381-393. doi: 10.1007/s00417-023-06129-7. Epub 2023 Jun 12. Graefes Arch Clin Exp Ophthalmol. 2024. PMID: 37306732 Review.
METHOD: We identified 24 studies that illustrated the clinical observations of the surgical approaches in interest. We included Descemet stripping only (DSO), Descemet membrane transplantation (DMT) where Descement membrane alone instead of corneal endothelium with cells i …
METHOD: We identified 24 studies that illustrated the clinical observations of the surgical approaches in interest. We included Desce …
Surgical Management of Fuchs Endothelial Corneal Dystrophy: A Treatment Algorithm and Individual Patient Meta-Analysis of Descemet Stripping Only.
Din N, Cohen E, Popovic M, Mimouni M, Trinh T, Gouvea L, Alshaker S, Ong Tone S, Chan CC, Slomovic AR. Din N, et al. Cornea. 2022 Sep 1;41(9):1188-1195. doi: 10.1097/ICO.0000000000002975. Epub 2022 Jan 25. Cornea. 2022. PMID: 35942547
PURPOSE: This study aims to determine predictive factors for success of Descemet stripping only (DSO) in Fuchs corneal endothelial dystrophy and propose a DSO treatment algorithm. ...CONCLUSIONS: DSO has a role in the treatment of a subset of patients …
PURPOSE: This study aims to determine predictive factors for success of Descemet stripping only (DSO) in Fuchs corneal endo …
New therapeutic modality for corneal endothelial disease using Rho-associated kinase inhibitor eye drops.
Koizumi N, Okumura N, Ueno M, Kinoshita S. Koizumi N, et al. Cornea. 2014 Nov;33 Suppl 11:S25-31. doi: 10.1097/ICO.0000000000000240. Cornea. 2014. PMID: 25289721 Review.
A pilot clinical study was performed at the Kyoto Prefectural University of Medicine, and the effects of Y-27632 eye drops after transcorneal freezing were evaluated in 8 patients with corneal endothelial dysfunction. We observed a positive effect of ROCK inhibitor eye dro …
A pilot clinical study was performed at the Kyoto Prefectural University of Medicine, and the effects of Y-27632 eye drops after transcornea …
Energy Shortage in Human and Mouse Models of SLC4A11-Associated Corneal Endothelial Dystrophies.
Zhang W, Frausto R, Chung DD, Griffis CG, Kao L, Chen A, Azimov R, Sampath AP, Kurtz I, Aldave AJ. Zhang W, et al. Invest Ophthalmol Vis Sci. 2020 Jul 1;61(8):39. doi: 10.1167/iovs.61.8.39. Invest Ophthalmol Vis Sci. 2020. PMID: 32721020 Free PMC article.
Functional analyses were performed to investigate potential functional changes associated with the observed transcriptomic alterations. RESULTS: CTA revealed inhibition of cell metabolism and ion transport function as well as mitochondrial dysfunction, leading to reduced a …
Functional analyses were performed to investigate potential functional changes associated with the observed transcriptomic alteration …
Clinical study of Fuchs corneal endothelial dystrophy leading to penetrating keratoplasty: a 30-year experience.
Afshari NA, Pittard AB, Siddiqui A, Klintworth GK. Afshari NA, et al. Arch Ophthalmol. 2006 Jun;124(6):777-80. doi: 10.1001/archopht.124.6.777. Arch Ophthalmol. 2006. PMID: 16769829
OBJECTIVE: To review 30 years' clinical experience with Fuchs corneal endothelial dystrophy leading to penetrating keratoplasty (PK). METHODS: We reviewed the clinical records of patients diagnosed histopathologically as having Fuchs corneal endothe …
OBJECTIVE: To review 30 years' clinical experience with Fuchs corneal endothelial dystrophy leading to penetrating kera …
Predictive Factors for Clinical Outcomes after Primary Descemet's Membrane Endothelial Keratoplasty for Fuchs' Endothelial Dystrophy.
Brockmann T, Pilger D, Brockmann C, Maier AB, Bertelmann E, Torun N. Brockmann T, et al. Curr Eye Res. 2019 Feb;44(2):147-153. doi: 10.1080/02713683.2018.1538459. Epub 2018 Oct 29. Curr Eye Res. 2019. PMID: 30339062

METHODS: In a prospective observational study, 108 eyes with Fuchs' endothelial dystrophy underwent a primary DMEK. ...A significant influence of the preoperative CCT on postoperative BCVAs and CCTs was observed (r = 0.299, p = 0.014 and r = 0.507, p < 0.001, res

…
METHODS: In a prospective observational study, 108 eyes with Fuchs' endothelial dystrophy underwent a primary DMEK. ...A significant …
Descemet Membrane Endothelial Keratoplasty: Outcomes in the First Year of Experience.
Altınörs DD, Asena L. Altınörs DD, et al. Exp Clin Transplant. 2018 Mar;16 Suppl 1(Suppl 1):101-103. doi: 10.6002/ect.TOND-TDTD2017.O38. Exp Clin Transplant. 2018. PMID: 29528002 Free article.
RESULTS: Five eyes of 5 patients (4 female, 1 male) with a mean age of 53.4 12.7 years were included. Cause of endothelial dysfunction included corneal endothelial dystrophy in 3 patients, pseudophakic bullous keratopathy in 1 patient, and endothelial graft f …
RESULTS: Five eyes of 5 patients (4 female, 1 male) with a mean age of 53.4 12.7 years were included. Cause of endothelial dysfunction inclu …
Observation of nine previously reported and 10 non-reported SLC4A11 mutations among 20 Iranian CHED probands and identification of an MPDZ mutation as possible cause of CHED and FECD in one family.
Moazzeni H, Javadi MA, Asgari D, Khani M, Emami M, Moghadam A, Panahi-Bazaz MR, Hosseini Tehrani M, Karimian F, Hosseini B, Nekuie Moghadam T, Hassanpour H, Akbari MT, Elahi E. Moazzeni H, et al. Br J Ophthalmol. 2020 Nov;104(11):1621-1628. doi: 10.1136/bjophthalmol-2019-314377. Epub 2019 Aug 16. Br J Ophthalmol. 2020. PMID: 31420327
RESULTS: Nine previously reported and 10 unreported SLC4A11 mutations were observed among 20 patients; a mutation was not found in one patient. ...CONCLUSION: SLC4A11 mutations are the usual cause of CHED in Iranians. The 10 novel mutations observed contribute signi …
RESULTS: Nine previously reported and 10 unreported SLC4A11 mutations were observed among 20 patients; a mutation was not found in on …
Corneal transplant rejection rate and severity after endothelial keratoplasty.
Allan BD, Terry MA, Price FW Jr, Price MO, Griffin NB, Claesson M. Allan BD, et al. Cornea. 2007 Oct;26(9):1039-42. doi: 10.1097/ICO.0b013e31812f66e5. Cornea. 2007. PMID: 17893530
METHODS: Anonymized data from consecutive cases of EK [deep lamellar (DLEK) or Descemet stripping (DSEK)] for Fuchs corneal endothelial dystrophy or pseudophakic bullous keratopathy operated on before August 2004 were collected in 4 participating centers. ... …
METHODS: Anonymized data from consecutive cases of EK [deep lamellar (DLEK) or Descemet stripping (DSEK)] for Fuchs corneal endoth …
21 results