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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1976 1
1979 2
1980 1
1982 1
1984 1
1985 2
1987 1
1989 1
1991 2
1992 3
1993 4
1994 3
1995 6
1996 5
1997 7
1998 9
1999 11
2000 15
2001 10
2002 10
2003 15
2004 17
2005 20
2006 17
2007 17
2008 28
2009 18
2010 22
2011 24
2012 26
2013 24
2014 26
2015 30
2016 26
2017 25
2018 28
2019 27
2020 28
2021 33
2022 16
2023 7
2024 5

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512 results

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Quoted phrase not found in phrase index: "Coronary heart disease, susceptibility to, 6"
Page 1
Smoking and heart failure: a Mendelian randomization and mediation analysis.
Lu Y, Xu Z, Georgakis MK, Wang Z, Lin H, Zheng L. Lu Y, et al. ESC Heart Fail. 2021 Jun;8(3):1954-1965. doi: 10.1002/ehf2.13248. Epub 2021 Mar 3. ESC Heart Fail. 2021. PMID: 33656795 Free PMC article.
AIMS: We performed a Mendelian randomization (MR) study to elucidate the associations of ever smoking, lifelong smoking duration, and smoking cessation with heart failure (HF) risk. ...The mediation effects of coronary artery disease and atrial fibrill …
AIMS: We performed a Mendelian randomization (MR) study to elucidate the associations of ever smoking, lifelong smoking duration, and …
First International Consensus on the diagnosis and management of fibromuscular dysplasia.
Gornik HL, Persu A, Adlam D, Aparicio LS, Azizi M, Boulanger M, Bruno RM, de Leeuw P, Fendrikova-Mahlay N, Froehlich J, Ganesh SK, Gray BH, Jamison C, Januszewicz A, Jeunemaitre X, Kadian-Dodov D, Kim ES, Kovacic JC, Mace P, Morganti A, Sharma A, Southerland AM, Touzé E, van der Niepen P, Wang J, Weinberg I, Wilson S, Olin JW, Plouin PF. Gornik HL, et al. Vasc Med. 2019 Apr;24(2):164-189. doi: 10.1177/1358863X18821816. Epub 2019 Jan 16. Vasc Med. 2019. PMID: 30648921 Review.
This document updates previous consensus documents/scientific statements on FMD published in 2014 with full harmonization of the position of European and US experts. In addition to practical consensus-based clinical recommendations, including a consensus protocol for cathe …
This document updates previous consensus documents/scientific statements on FMD published in 2014 with full harmonization of the position of …
Mendelian randomization in cardiometabolic disease: challenges in evaluating causality.
Holmes MV, Ala-Korpela M, Smith GD. Holmes MV, et al. Nat Rev Cardiol. 2017 Oct;14(10):577-590. doi: 10.1038/nrcardio.2017.78. Epub 2017 Jun 1. Nat Rev Cardiol. 2017. PMID: 28569269 Free PMC article. Review.
Mendelian randomization (MR) is a burgeoning field that involves the use of genetic variants to assess causal relationships between exposures and outcomes. ...In this Review, we describe some of these challenges in interpreting MR analyses, including those from studies usi …
Mendelian randomization (MR) is a burgeoning field that involves the use of genetic variants to assess causal relationships between e …
Sleep Duration and Myocardial Infarction.
Daghlas I, Dashti HS, Lane J, Aragam KG, Rutter MK, Saxena R, Vetter C. Daghlas I, et al. J Am Coll Cardiol. 2019 Sep 10;74(10):1304-1314. doi: 10.1016/j.jacc.2019.07.022. J Am Coll Cardiol. 2019. PMID: 31488267 Free PMC article.
BACKGROUND: Observational studies suggest associations between extremes of sleep duration and myocardial infarction (MI), but the causal contribution of sleep to MI and its potential to mitigate genetic predisposition to coronary disease is unclear. OBJECTIVES: This …
BACKGROUND: Observational studies suggest associations between extremes of sleep duration and myocardial infarction (MI), but the causal con …
Genetics of obesity: what genetic association studies have taught us about the biology of obesity and its complications.
Goodarzi MO. Goodarzi MO. Lancet Diabetes Endocrinol. 2018 Mar;6(3):223-236. doi: 10.1016/S2213-8587(17)30200-0. Epub 2017 Sep 14. Lancet Diabetes Endocrinol. 2018. PMID: 28919064 Review.
Gene by environment and lifestyle interaction analyses have revealed that our increasingly obesogenic environment might be amplifying genetic risk for obesity, yet those at highest risk could mitigate this risk by increasing physical activity and possibly by avoiding specific die …
Gene by environment and lifestyle interaction analyses have revealed that our increasingly obesogenic environment might be amplifying geneti …
Shared genetic risk factors and causal association between psoriasis and coronary artery disease.
Patrick MT, Li Q, Wasikowski R, Mehta N, Gudjonsson JE, Elder JT, Zhou X, Tsoi LC. Patrick MT, et al. Nat Commun. 2022 Nov 2;13(1):6565. doi: 10.1038/s41467-022-34323-4. Nat Commun. 2022. PMID: 36323703 Free PMC article.
Psoriasis and coronary artery disease (CAD) are related comorbidities that are well established, but whether a genetic basis underlies this is not well studied. ...Chronic systemic inflammation has been associated with CAD and myocardial infarction, and Mendelian …
Psoriasis and coronary artery disease (CAD) are related comorbidities that are well established, but whether a genetic basis u …
Dyslipidemia, inflammation, calcification, and adiposity in aortic stenosis: a genome-wide study.
Yu Chen H, Dina C, Small AM, Shaffer CM, Levinson RT, Helgadóttir A, Capoulade R, Munter HM, Martinsson A, Cairns BJ, Trudsø LC, Hoekstra M, Burr HA, Marsh TW, Damrauer SM, Dufresne L, Le Scouarnec S, Messika-Zeitoun D, Ranatunga DK, Whitmer RA, Bonnefond A, Sveinbjornsson G, Daníelsen R, Arnar DO, Thorgeirsson G, Thorsteinsdottir U, Gudbjartsson DF, Hólm H, Ghouse J, Olesen MS, Christensen AH, Mikkelsen S, Jacobsen RL, Dowsett J, Pedersen OBV, Erikstrup C, Ostrowski SR; Regeneron Genetics Center; O'Donnell CJ, Budoff MJ, Gudnason V, Post WS, Rotter JI, Lathrop M, Bundgaard H, Johansson B, Ljungberg J, Näslund U, Le Tourneau T, Smith JG, Wells QS, Söderberg S, Stefánsson K, Schott JJ, Rader DJ, Clarke R, Engert JC, Thanassoulis G. Yu Chen H, et al. Eur Heart J. 2023 Jun 1;44(21):1927-1939. doi: 10.1093/eurheartj/ehad142. Eur Heart J. 2023. PMID: 37038246 Free PMC article.
The aim of this study was to discover novel genetic contributors to AS and to integrate functional, expression, and cross-phenotype data to identify mechanisms of AS. METHODS AND RESULTS: A genome-wide meta-analysis of 11.6 million variants in 10 cohorts involving 653 867 …
The aim of this study was to discover novel genetic contributors to AS and to integrate functional, expression, and cross-phenotype data to …
Major depressive disorder and cardiometabolic diseases: a bidirectional Mendelian randomisation study.
Tang B, Yuan S, Xiong Y, He Q, Larsson SC. Tang B, et al. Diabetologia. 2020 Jul;63(7):1305-1311. doi: 10.1007/s00125-020-05131-6. Epub 2020 Apr 8. Diabetologia. 2020. PMID: 32270255 Free PMC article.
AIMS/HYPOTHESIS: Observational studies have shown a bidirectional association between major depressive disorder (MDD) and cardiometabolic diseases. We conducted a two-sample bidirectional Mendelian randomisation (MR) study to assess the causal associations of MDD with type …
AIMS/HYPOTHESIS: Observational studies have shown a bidirectional association between major depressive disorder (MDD) and cardiometabolic di …
Effect of long-term exposure to lower low-density lipoprotein cholesterol beginning early in life on the risk of coronary heart disease: a Mendelian randomization analysis.
Ference BA, Yoo W, Alesh I, Mahajan N, Mirowska KK, Mewada A, Kahn J, Afonso L, Williams KA Sr, Flack JM. Ference BA, et al. J Am Coll Cardiol. 2012 Dec 25;60(25):2631-9. doi: 10.1016/j.jacc.2012.09.017. Epub 2012 Oct 17. J Am Coll Cardiol. 2012. PMID: 23083789 Free article. Review.
OBJECTIVES: The purpose of this study was to estimate the effect of long-term exposure to lower plasma low-density lipoprotein cholesterol (LDL-C) on the risk of coronary heart disease (CHD). BACKGROUND: LDL-C is causally related to the risk of CHD. ...METHOD …
OBJECTIVES: The purpose of this study was to estimate the effect of long-term exposure to lower plasma low-density lipoprotein cholesterol ( …
Evaluating the relationship between alcohol consumption, tobacco use, and cardiovascular disease: A multivariable Mendelian randomization study.
Rosoff DB, Davey Smith G, Mehta N, Clarke TK, Lohoff FW. Rosoff DB, et al. PLoS Med. 2020 Dec 4;17(12):e1003410. doi: 10.1371/journal.pmed.1003410. eCollection 2020 Dec. PLoS Med. 2020. PMID: 33275596 Free PMC article.
Conversely, genetically predicted smoking was associated with increased TRG (beta 0.097, 95% CI, 0.014-0.027, P value = 6.59 10-12). Alcohol consumption was also associated with increased myocardial infarction (MI) and coronary heart disease (CHD) risk …
Conversely, genetically predicted smoking was associated with increased TRG (beta 0.097, 95% CI, 0.014-0.027, P value = 6.59 10-12). …
512 results