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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1974 1
1978 1
1980 1
1983 2
1984 3
1985 1
1986 2
1987 4
1988 2
1989 1
1990 2
1991 4
1992 6
1993 3
1994 6
1995 5
1996 10
1997 12
1998 14
1999 13
2000 25
2001 18
2002 19
2003 20
2004 37
2005 29
2006 35
2007 30
2008 38
2009 40
2010 35
2011 54
2012 65
2013 57
2014 54
2015 54
2016 57
2017 65
2018 62
2019 53
2020 66
2021 59
2022 35
2023 34
2024 24

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1,027 results

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Quoted phrase not found in phrase index: "Coronary heart disease, susceptibility to, 1"
Page 1
Evaluating the relationship between circulating lipoprotein lipids and apolipoproteins with risk of coronary heart disease: A multivariable Mendelian randomisation analysis.
Richardson TG, Sanderson E, Palmer TM, Ala-Korpela M, Ference BA, Davey Smith G, Holmes MV. Richardson TG, et al. PLoS Med. 2020 Mar 23;17(3):e1003062. doi: 10.1371/journal.pmed.1003062. eCollection 2020 Mar. PLoS Med. 2020. PMID: 32203549 Free PMC article.
BACKGROUND: Circulating lipoprotein lipids cause coronary heart disease (CHD). However, the precise way in which one or more lipoprotein lipid-related entities account for this relationship remains unclear. ...Assessed individually using MR, LDL cholesterol ( …
BACKGROUND: Circulating lipoprotein lipids cause coronary heart disease (CHD). However, the precise way in which one or …
Diet-Derived Circulating Antioxidants and Risk of Coronary Heart Disease: A Mendelian Randomization Study.
Luo J, le Cessie S, van Heemst D, Noordam R. Luo J, et al. J Am Coll Cardiol. 2021 Jan 5;77(1):45-54. doi: 10.1016/j.jacc.2020.10.048. J Am Coll Cardiol. 2021. PMID: 33413940 Free article.
BACKGROUND: Previously, observational studies have identified associations between higher levels of dietary-derived antioxidants and lower risk of coronary heart disease (CHD), whereas randomized clinical trials showed no reduction in CHD risk f …
BACKGROUND: Previously, observational studies have identified associations between higher levels of dietary-derived antioxidants and lower r …
Mendelian randomization in cardiometabolic disease: challenges in evaluating causality.
Holmes MV, Ala-Korpela M, Smith GD. Holmes MV, et al. Nat Rev Cardiol. 2017 Oct;14(10):577-590. doi: 10.1038/nrcardio.2017.78. Epub 2017 Jun 1. Nat Rev Cardiol. 2017. PMID: 28569269 Free PMC article. Review.
Mendelian randomization (MR) is a burgeoning field that involves the use of genetic variants to assess causal relationships between exposures and outcomes. ...In this Review, we describe some of these challenges in interpreting MR analyses, including those from studies usi …
Mendelian randomization (MR) is a burgeoning field that involves the use of genetic variants to assess causal relationships between e …
Sleep Duration and Myocardial Infarction.
Daghlas I, Dashti HS, Lane J, Aragam KG, Rutter MK, Saxena R, Vetter C. Daghlas I, et al. J Am Coll Cardiol. 2019 Sep 10;74(10):1304-1314. doi: 10.1016/j.jacc.2019.07.022. J Am Coll Cardiol. 2019. PMID: 31488267 Free PMC article.
BACKGROUND: Observational studies suggest associations between extremes of sleep duration and myocardial infarction (MI), but the causal contribution of sleep to MI and its potential to mitigate genetic predisposition to coronary disease is unclear. OBJECTIVES: This …
BACKGROUND: Observational studies suggest associations between extremes of sleep duration and myocardial infarction (MI), but the causal con …
Sarcopenia-related traits and coronary artery disease: a bi-directional Mendelian randomization study.
Liu HM, Zhang Q, Shen WD, Li BY, Lv WQ, Xiao HM, Deng HW. Liu HM, et al. Aging (Albany NY). 2020 Feb 16;12(4):3340-3353. doi: 10.18632/aging.102815. Epub 2020 Feb 16. Aging (Albany NY). 2020. PMID: 32062614 Free PMC article.
Previous Mendelian randomization (MR) studies have yielded a conflicting causal relationship between sarcopenia and coronary artery disease (CAD), and lack the association of CAD with sarcopenia. ...IVW analysis showed that higher handgrip strength reduces ri …
Previous Mendelian randomization (MR) studies have yielded a conflicting causal relationship between sarcopenia and coronary a …
Genetic Liability to Rheumatoid Arthritis in Relation to Coronary Artery Disease and Stroke Risk.
Yuan S, Carter P, Mason AM, Yang F, Burgess S, Larsson SC. Yuan S, et al. Arthritis Rheumatol. 2022 Oct;74(10):1638-1647. doi: 10.1002/art.42239. Epub 2022 Aug 17. Arthritis Rheumatol. 2022. PMID: 35583917 Free PMC article.
OBJECTIVE: To assess the causality of the associations of rheumatoid arthritis (RA) with coronary artery disease (CAD) and stroke using the Mendelian randomization approach. ...RESULTS: Genetic liability to RA was associated with an increased risk of CAD and …
OBJECTIVE: To assess the causality of the associations of rheumatoid arthritis (RA) with coronary artery disease (CAD) and str …
Shared genetic risk factors and causal association between psoriasis and coronary artery disease.
Patrick MT, Li Q, Wasikowski R, Mehta N, Gudjonsson JE, Elder JT, Zhou X, Tsoi LC. Patrick MT, et al. Nat Commun. 2022 Nov 2;13(1):6565. doi: 10.1038/s41467-022-34323-4. Nat Commun. 2022. PMID: 36323703 Free PMC article.
Psoriasis and coronary artery disease (CAD) are related comorbidities that are well established, but whether a genetic basis underlies this is not well studied. ...Chronic systemic inflammation has been associated with CAD and myocardial infarction, and Mendelian …
Psoriasis and coronary artery disease (CAD) are related comorbidities that are well established, but whether a genetic basis u …
Urate, Blood Pressure, and Cardiovascular Disease: Evidence From Mendelian Randomization and Meta-Analysis of Clinical Trials.
Gill D, Cameron AC, Burgess S, Li X, Doherty DJ, Karhunen V, Abdul-Rahim AH, Taylor-Rowan M, Zuber V, Tsao PS, Klarin D; VA Million Veteran Program; Evangelou E, Elliott P, Damrauer SM, Quinn TJ, Dehghan A, Theodoratou E, Dawson J, Tzoulaki I. Gill D, et al. Hypertension. 2021 Feb;77(2):383-392. doi: 10.1161/HYPERTENSIONAHA.120.16547. Epub 2020 Dec 28. Hypertension. 2021. PMID: 33356394 Free PMC article.
The main Mendelian randomization analyses showed that every 1-SD increase in genetically predicted serum urate was associated with an increased risk of coronary heart disease (odds ratio, 1.19 [95% CI, 1.10-1.30]; P=410(-5)) …
The main Mendelian randomization analyses showed that every 1-SD increase in genetically predicted serum urate was associated …
Major depressive disorder and cardiometabolic diseases: a bidirectional Mendelian randomisation study.
Tang B, Yuan S, Xiong Y, He Q, Larsson SC. Tang B, et al. Diabetologia. 2020 Jul;63(7):1305-1311. doi: 10.1007/s00125-020-05131-6. Epub 2020 Apr 8. Diabetologia. 2020. PMID: 32270255 Free PMC article.
AIMS/HYPOTHESIS: Observational studies have shown a bidirectional association between major depressive disorder (MDD) and cardiometabolic diseases. We conducted a two-sample bidirectional Mendelian randomisation (MR) study to assess the causal associations of MDD with type …
AIMS/HYPOTHESIS: Observational studies have shown a bidirectional association between major depressive disorder (MDD) and cardiometabolic di …
Causal Association Between Anemia and Cardiovascular Disease: A 2-Sample Bidirectional Mendelian Randomization Study.
Gan T, Hu J, Liu W, Li C, Xu Q, Wang Y, Lu S, Aledan AKO, Wang Y, Wang Z. Gan T, et al. J Am Heart Assoc. 2023 Jun 20;12(12):e029689. doi: 10.1161/JAHA.123.029689. Epub 2023 Jun 10. J Am Heart Assoc. 2023. PMID: 37301769 Free PMC article.
We extracted summary statistics data for anemia, heart failure (HF), coronary artery disease (CAD), atrial fibrillation, any stroke, and any ischemic stroke (AIS) from relevant published genome-wide association studies. ...The ORs of HF, CAD, and AIS were …
We extracted summary statistics data for anemia, heart failure (HF), coronary artery disease (CAD), atrial fibrillation …
1,027 results