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Ado-trastuzumab emtansine associated spider telangiectasia.
Gursoy P, Acar A, Acikalin T. Gursoy P, et al. J Oncol Pharm Pract. 2022 Jun;28(4):986-988. doi: 10.1177/10781552211073878. Epub 2022 Jan 18. J Oncol Pharm Pract. 2022. PMID: 35040682
Human epidermal growth factor receptor 2 (HER2) positivity rate is 20% and generally has a poor prognosis. Ado-trastuzumab emtansine (T-DM1) is an antibody-drug conjugate consisting of HER2 target monoclonal antibody trastuzumab and microtubule inhibitor emtansine. ...
Human epidermal growth factor receptor 2 (HER2) positivity rate is 20% and generally has a poor prognosis. Ado-trastuzumab emtansine …
Variation in telangiectasia predisposing genes is associated with overall radiation toxicity.
Tanteles GA, Murray RJ, Mills J, Barwell J, Chakraborti P, Chan S, Cheung KL, Ennis D, Khurshid N, Lambert K, Machhar R, Meisuria M, Osman A, Peat I, Sahota H, Woodings P, Talbot CJ, Symonds RP. Tanteles GA, et al. Int J Radiat Oncol Biol Phys. 2012 Nov 15;84(4):1031-6. doi: 10.1016/j.ijrobp.2012.02.018. Epub 2012 Jun 6. Int J Radiat Oncol Biol Phys. 2012. PMID: 22677372
The predisposing variation in the ATM gene will need to be better defined to optimize it as a predictive marker for assessing radiotherapy late effects....
The predisposing variation in the ATM gene will need to be better defined to optimize it as a predictive marker for assessing radioth …
Lung disease in ataxia-telangiectasia.
Bott L, Lebreton J, Thumerelle C, Cuvellier J, Deschildre A, Sardet A. Bott L, et al. Acta Paediatr. 2007 Jul;96(7):1021-4. doi: 10.1111/j.1651-2227.2007.00338.x. Epub 2007 May 24. Acta Paediatr. 2007. PMID: 17524020
DISCUSSION: Recurrent sino-pulmonary manifestations precede neurological complications, but the severity of neuro-degeneration and pulmonary disease were not correlated. Pulmonary status was a prognosis factor. Immunodeficiency was the main, but not the only, aetiology for …
DISCUSSION: Recurrent sino-pulmonary manifestations precede neurological complications, but the severity of neuro-degeneration and pulmonary …
Acute paraplegia due to spinal arteriovenous fistula in two patients with hereditary hemorrhagic telangiectasia.
Poisson A, Vasdev A, Brunelle F, Plauchu H, Dupuis-Girod S; French Italian HHT network. Poisson A, et al. Eur J Pediatr. 2009 Feb;168(2):135-9. doi: 10.1007/s00431-008-0863-2. Epub 2008 Nov 20. Eur J Pediatr. 2009. PMID: 19020899 Review.
In most of the cases reported, the clinical presentation was acute in the pediatric population and insidious during adulthood. The prognosis of spinal AVM mainly depends on the presence or not of medullar signs and symptoms and on the delay before treatment. ...
In most of the cases reported, the clinical presentation was acute in the pediatric population and insidious during adulthood. The progno …
Prominent oromandibular dystonia and pharyngeal telangiectasia in atypical ataxia telangiectasia.
Carrillo F, Schneider SA, Taylor AM, Srinivasan V, Kapoor R, Bhatia KP. Carrillo F, et al. Cerebellum. 2009 Mar;8(1):22-7. doi: 10.1007/s12311-008-0055-7. Cerebellum. 2009. PMID: 18846412
In this paper, we report a case of A-T with an atypically mild and slowly progressive disease course. Although by history there was mild gait clumsiness in early childhood, the leading problem was that of dystonia with onset at age 15, in the absence of gross gait imbalanc …
In this paper, we report a case of A-T with an atypically mild and slowly progressive disease course. Although by history there was m …