Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My NCBI Filters

Results by year

Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1971 1
1974 1
1975 1
1976 2
1978 4
1979 5
1980 2
1981 7
1982 4
1983 5
1984 7
1985 10
1986 15
1987 28
1988 32
1989 43
1990 51
1991 57
1992 76
1993 103
1994 116
1995 129
1996 167
1997 125
1998 162
1999 213
2000 185
2001 267
2002 300
2003 269
2004 288
2005 343
2006 338
2007 341
2008 432
2009 443
2010 558
2011 614
2012 670
2013 659
2014 728
2015 751
2016 819
2017 816
2018 878
2019 865
2020 922
2021 922
2022 729
2023 679
2024 239

Text availability

Article attribute

Article type

Publication date

Search Results

13,664 results

Results by year

Filters applied: . Clear all
Page 1
PARP inhibitors: Synthetic lethality in the clinic.
Lord CJ, Ashworth A. Lord CJ, et al. Science. 2017 Mar 17;355(6330):1152-1158. doi: 10.1126/science.aam7344. Epub 2017 Mar 16. Science. 2017. PMID: 28302823 Free PMC article. Review.
Nevertheless, the preclinical discovery of PARPi synthetic lethality and the route to clinical approval provide interesting lessons for the development of other therapies. Here, we discuss current knowledge of PARP inhibitors and potential ways to maximize their clinica …
Nevertheless, the preclinical discovery of PARPi synthetic lethality and the route to clinical approval provide interesting lessons f …
Glioblastoma in adults: a Society for Neuro-Oncology (SNO) and European Society of Neuro-Oncology (EANO) consensus review on current management and future directions.
Wen PY, Weller M, Lee EQ, Alexander BM, Barnholtz-Sloan JS, Barthel FP, Batchelor TT, Bindra RS, Chang SM, Chiocca EA, Cloughesy TF, DeGroot JF, Galanis E, Gilbert MR, Hegi ME, Horbinski C, Huang RY, Lassman AB, Le Rhun E, Lim M, Mehta MP, Mellinghoff IK, Minniti G, Nathanson D, Platten M, Preusser M, Roth P, Sanson M, Schiff D, Short SC, Taphoorn MJB, Tonn JC, Tsang J, Verhaak RGW, von Deimling A, Wick W, Zadeh G, Reardon DA, Aldape KD, van den Bent MJ. Wen PY, et al. Neuro Oncol. 2020 Aug 17;22(8):1073-1113. doi: 10.1093/neuonc/noaa106. Neuro Oncol. 2020. PMID: 32328653 Free PMC article. Review.
In addition, novel therapies such as targeted molecular therapies, agents targeting DNA damage response and metabolism, immunotherapies, and viral therapies will be reviewed, as well as the current challenges and future directions for research....
In addition, novel therapies such as targeted molecular therapies, agents targeting DNA damage response and metabolism, immuno …
Systemic Therapy for Metastatic Pancreatic Cancer.
Ettrich TJ, Seufferlein T. Ettrich TJ, et al. Curr Treat Options Oncol. 2021 Oct 19;22(11):106. doi: 10.1007/s11864-021-00895-4. Curr Treat Options Oncol. 2021. PMID: 34665339 Free PMC article. Review.
Limited data in mPDACs shows that only a part of the already small subgroup of MSI-H mPDACs (frequency about 1%) appears to benefit substantially from a checkpoint inhibitor treatment. The identification of further subgroups, e.g., tumors with DNA damage repair defi …
Limited data in mPDACs shows that only a part of the already small subgroup of MSI-H mPDACs (frequency about 1%) appears to benefit substant …
The antioxidant, immunomodulatory, and anti-inflammatory activities of Spirulina: an overview.
Wu Q, Liu L, Miron A, Klímová B, Wan D, Kuča K. Wu Q, et al. Arch Toxicol. 2016 Aug;90(8):1817-40. doi: 10.1007/s00204-016-1744-5. Epub 2016 Jun 3. Arch Toxicol. 2016. PMID: 27259333 Review.
Spirulina activates cellular antioxidant enzymes, inhibits lipid peroxidation and DNA damage, scavenges free radicals, and increases the activity of superoxide dismutase and catalase. Notably, there appears to be a threshold level above which Spirulina will taper of …
Spirulina activates cellular antioxidant enzymes, inhibits lipid peroxidation and DNA damage, scavenges free radicals, and inc …
Talazoparib plus enzalutamide in metastatic castration-resistant prostate cancer: TALAPRO-2 phase III study design.
Agarwal N, Azad A, Shore ND, Carles J, Fay AP, Dunshee C, Karsh LI, Paccagnella ML, Santo ND, Elmeliegy M, Lin X, Czibere A, Fizazi K. Agarwal N, et al. Future Oncol. 2022 Feb;18(4):425-436. doi: 10.2217/fon-2021-0811. Epub 2022 Jan 26. Future Oncol. 2022. PMID: 35080190 Free article.
Here, we describe the design and rationale of the multinational, phase III, two-part TALAPRO-2 study comparing talazoparib plus enzalutamide versus placebo plus enzalutamide as a first-line treatment for patients with mCRPC with or without DNA damage response (DDR) …
Here, we describe the design and rationale of the multinational, phase III, two-part TALAPRO-2 study comparing talazoparib plus enzalutamide …
Nicotinamide for photoprotection and skin cancer chemoprevention: A review of efficacy and safety.
Snaidr VA, Damian DL, Halliday GM. Snaidr VA, et al. Exp Dermatol. 2019 Feb;28 Suppl 1:15-22. doi: 10.1111/exd.13819. Exp Dermatol. 2019. PMID: 30698874 Review.
This enhances DNA repair and reduces UV-induced suppression of immunity. Randomised controlled clinical trials have also shown that nicotinamide reduces transepidermal water loss and the development of new non-melanoma skin cancers in high-risk humans. ...
This enhances DNA repair and reduces UV-induced suppression of immunity. Randomised controlled clinical trials have also shown …
Cellular senescence and the senescent secretory phenotype: therapeutic opportunities.
Tchkonia T, Zhu Y, van Deursen J, Campisi J, Kirkland JL. Tchkonia T, et al. J Clin Invest. 2013 Mar;123(3):966-72. doi: 10.1172/JCI64098. Epub 2013 Mar 1. J Clin Invest. 2013. PMID: 23454759 Free PMC article. Review.
We review the mechanisms that induce senescence and the SASP, their associations with chronic disease and frailty, therapeutic opportunities based on targeting senescent cells and the SASP, and potential paths to developing clinical interventions....
We review the mechanisms that induce senescence and the SASP, their associations with chronic disease and frailty, therapeutic opportunities …
Hass avocado composition and potential health effects.
Dreher ML, Davenport AJ. Dreher ML, et al. Crit Rev Food Sci Nutr. 2013;53(7):738-50. doi: 10.1080/10408398.2011.556759. Crit Rev Food Sci Nutr. 2013. PMID: 23638933 Free PMC article. Review.
The avocado oil consists of 71% monounsaturated fatty acids (MUFA), 13% polyunsaturated fatty acids (PUFA), and 16% saturated fatty acids (SFA), which helps to promote healthy blood lipid profiles and enhance the bioavailability of fat soluble vitamins and phytochemicals from the …
The avocado oil consists of 71% monounsaturated fatty acids (MUFA), 13% polyunsaturated fatty acids (PUFA), and 16% saturated fatty acids (S …
Tumour necrosis factor and cancer.
Balkwill F. Balkwill F. Nat Rev Cancer. 2009 May;9(5):361-71. doi: 10.1038/nrc2628. Epub 2009 Apr 3. Nat Rev Cancer. 2009. PMID: 19343034 Review.
13,664 results
You have reached the last available page of results. Please see the User Guide for more information.