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Page 1
Childhood Solitary Cutaneous Mastocytoma: Clinical Manifestations, Diagnosis, Evaluation, and Management.
Leung AKC, Lam JM, Leong KF. Leung AKC, et al. Curr Pediatr Rev. 2019;15(1):42-46. doi: 10.2174/1573396315666181120163952. Curr Pediatr Rev. 2019. PMID: 30465511 Free PMC article. Review.
BACKGROUND: The diagnosis of solitary cutaneous mastocytoma is mainly clinical, based on lesion morphology, the presence of a positive Darier sign, and the absence of systemic involvement. ...Reassurance and avoidance of triggering factors suffice in most cas …
BACKGROUND: The diagnosis of solitary cutaneous mastocytoma is mainly clinical, based on lesion morphology, the presence of a positiv …
Darier sign in a teenager with primary cutaneous marginal zone lymphoma.
Leonard N, Lal K, Luffman C, O'Donnell P, Jolley L, Belazarian L. Leonard N, et al. Pediatr Dermatol. 2021 Mar;38(2):494-496. doi: 10.1111/pde.14488. Epub 2020 Dec 18. Pediatr Dermatol. 2021. PMID: 33336458
An adolescent male presented with dermal nodules on the arms, legs, and back with a positive Darier sign, ultimately diagnosed as PCMZL. The nodules demonstrated a partial response to doxycycline in the setting of prior Lyme disease followed by a complete response t …
An adolescent male presented with dermal nodules on the arms, legs, and back with a positive Darier sign, ultimately diagnosed …
Topical pimecrolimus for paediatric cutaneous mastocytosis.
Mashiah J, Harel A, Bodemer C, Hadj-Rabia S, Goldberg I, Sprecher E, Kutz A. Mashiah J, et al. Clin Exp Dermatol. 2018 Jul;43(5):559-565. doi: 10.1111/ced.13391. Epub 2018 Feb 20. Clin Exp Dermatol. 2018. PMID: 29460435
All patients were evaluated in a paediatric dermatology unit of a tertiary medical centre. Epidemiological, clinical and treatment data, including effectiveness and safety, were reviewed. ...Of the 119 papular lesions, 24 (16.4%) showed partial flattening and 56 (47%) beca …
All patients were evaluated in a paediatric dermatology unit of a tertiary medical centre. Epidemiological, clinical and treatment da …
Maculopapular Cutaneous Mastocytosis Successfully Treated with Omalizumab.
Tampouratzi L, Kanni T, Katsantonis J, Douvali T. Tampouratzi L, et al. Acta Dermatovenerol Croat. 2021 Apr;291(1):60-61. Acta Dermatovenerol Croat. 2021. PMID: 34477069
Treatment of MPCM depends on the presence of systemic involvement and/or the clinical symptoms of the disease itself. A 52-year-old woman was referred to us with pruritic brown red telangiectatic macules located on her arms, chest, and back (Figure 1, a, b, c) that had app …
Treatment of MPCM depends on the presence of systemic involvement and/or the clinical symptoms of the disease itself. A 52-year-old w …
Cutaneous mastocytosis: Two pediatric cases treated with topical pimecrolimus.
Correia O, Duarte AF, Quirino P, Azevedo R, Delgado L. Correia O, et al. Dermatol Online J. 2010 May 15;16(5):8. Dermatol Online J. 2010. PMID: 20492825
We report 2 patients, a 14-month-old girl and a 26-month-old boy, with localized cutaneous erythematous lesions with a positive Darier sign. In each, a punch biopsy confirmed the diagnosis of mastocytosis. ...An almost complete response was achieved after 4 months o …
We report 2 patients, a 14-month-old girl and a 26-month-old boy, with localized cutaneous erythematous lesions with a positive Darier …
A 6-month old with total body flushing and a macular-papular lesion.
Conrad H, Gausche-Hill M, Burbulys D. Conrad H, et al. Pediatr Emerg Care. 2007 May;23(5):321-3. doi: 10.1097/01.pec.0000270165.85862.12. Pediatr Emerg Care. 2007. PMID: 17505276
Erythema was most pronounced adjacent to the lesion, suggesting a positive Darier sign. Subsequent evaluation by a dermatologist confirmed the diagnosis, and the patient underwent no further therapy; however, the family was appropriately counseled on management if t …
Erythema was most pronounced adjacent to the lesion, suggesting a positive Darier sign. Subsequent evaluation by a dermatologi …