miR-219a-5p Regulates Rorβ During Osteoblast Differentiation and in Age-related Bone Loss.
Aquino-Martinez R, Farr JN, Weivoda MM, Negley BA, Onken JL, Thicke BS, Fulcer MM, Fraser DG, van Wijnen AJ, Khosla S, Monroe DG.
Aquino-Martinez R, et al.
J Bone Miner Res. 2019 Jan;34(1):135-144. doi: 10.1002/jbmr.3586. Epub 2018 Oct 15.
J Bone Miner Res. 2019.
PMID: 30321475
Free PMC article.
Importantly, we also found that miR-219a-5p expression was decreased in aged human bone biopsies compared with young controls, demonstrating that this phenomenon also occurs in aging bone in humans. Inhibition of miR-219a-5p in mouse calvarial osteoblasts led to inc …
Importantly, we also found that miR-219a-5p expression was decreased in aged human bone biopsies compared with young controls, demons …