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Primary immunodeficiencies underlying fungal infections.
Lanternier F, Cypowyj S, Picard C, Bustamante J, Lortholary O, Casanova JL, Puel A. Lanternier F, et al. Curr Opin Pediatr. 2013 Dec;25(6):736-47. doi: 10.1097/MOP.0000000000000031. Curr Opin Pediatr. 2013. PMID: 24240293 Free PMC article. Review.
Inborn errors of interleukin-17 immunity have recently been shown to underlie chronic mucocutaneous candidiasis (CMC), while inborn errors of caspase recruitment domain-containing protein 9 (CARD9) immunity underlie deep dermatophytosis and invasive candidiasis. SUM …
Inborn errors of interleukin-17 immunity have recently been shown to underlie chronic mucocutaneous candidiasis (CMC), while inborn errors o …
New clinical phenotypes of fungal infections in special hosts.
Pilmis B, Puel A, Lortholary O, Lanternier F. Pilmis B, et al. Clin Microbiol Infect. 2016 Aug;22(8):681-7. doi: 10.1016/j.cmi.2016.05.016. Epub 2016 May 26. Clin Microbiol Infect. 2016. PMID: 27237547 Free article. Review.
Conversely, some atypical fungal diseases can reveal new PID. Deep dermatophytosis, Candida central nervous system infections or gastrointestinal disease, or disseminated phaeohyphomycosis-revealed CARD9 deficiency. ...
Conversely, some atypical fungal diseases can reveal new PID. Deep dermatophytosis, Candida central nervous system infections …
A Unique Clinicopathological Manifestation of Fungal Infection: A Case Series of Deep Dermatophytosis in Immunosuppressed Patients.
Kershenovich R, Sherman S, Reiter O, Huss SR, Didkovsky E, Mimouni D, Hodak E, Segal R. Kershenovich R, et al. Am J Clin Dermatol. 2017 Oct;18(5):697-704. doi: 10.1007/s40257-017-0276-y. Am J Clin Dermatol. 2017. PMID: 28389891
BACKGROUND: Dermatophytes are the most common cause of superficial fungal infections in humans. Deep dermatophytosis, however, is rare, described to date only in isolated case reports, usually in the setting of systemic immunosuppression. OBJECTIVE: To present the 1 …
BACKGROUND: Dermatophytes are the most common cause of superficial fungal infections in humans. Deep dermatophytosis, however, …
Posaconazole treatment of extensive skin and nail dermatophytosis due to autosomal recessive deficiency of CARD9.
Jachiet M, Lanternier F, Rybojad M, Bagot M, Ibrahim L, Casanova JL, Puel A, Bouaziz JD. Jachiet M, et al. JAMA Dermatol. 2015 Feb;151(2):192-4. doi: 10.1001/jamadermatol.2014.2154. JAMA Dermatol. 2015. PMID: 25372963
IMPORTANCE: Deep dermatophytosis is a disease that involves dermatophytic infection of the dermis and/or lymph nodes and sometimes the central nervous system. Autosomal recessive deficiency of the CARD9 (caspase recruitment domain 9) protein has been described in 17 …
IMPORTANCE: Deep dermatophytosis is a disease that involves dermatophytic infection of the dermis and/or lymph nodes and somet …
Kerion of the vulva caused by Trichophyton mentagrophytes.
Bougrine A, Villeneuve-Tang C, Bouffard D, Rouleau D, Chartier S. Bougrine A, et al. J Cutan Med Surg. 2014 May-Jun;18(3):206-9. doi: 10.2310/7750.2013.13101. J Cutan Med Surg. 2014. PMID: 24800711
BACKGROUND: Deep dermatophytosis of genital skin is a rare clinical manifestation of infection by a common group of pathogens. ...Oral itraconazole was initiated on the basis of clinical suspicion and continued for a total of 6 weeks. CONCLUSION: Accurate diagnosis …
BACKGROUND: Deep dermatophytosis of genital skin is a rare clinical manifestation of infection by a common group of pathogens. …