Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My NCBI Filters

Results by year

Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1976 1
1978 1
1980 1
1983 1
1988 1
1990 1
1992 1
1994 1
1995 1
1996 1
1997 1
1999 2
2000 2
2001 1
2002 3
2003 1
2004 1
2006 1
2007 1
2010 1
2011 1
2012 2
2013 2
2014 2
2015 3
2016 2
2018 1
2019 2
2020 1
2021 2
2024 1

Text availability

Article attribute

Article type

Publication date

Search Results

37 results

Results by year

Filters applied: . Clear all
Quoted phrase not found in phrase index: "Defective DNA repair after ultraviolet radiation damage"
Page 1
Human DNA repair disorders in dermatology: A historical perspective, current concepts and new insight.
Moriwaki S. Moriwaki S. J Dermatol Sci. 2016 Feb;81(2):77-84. doi: 10.1016/j.jdermsci.2015.09.008. Epub 2015 Oct 1. J Dermatol Sci. 2016. PMID: 26493104 Review.
To protect against such UV-induced DNA damage, living organisms nicely retain "DNA repair systems", which can efficiently repair "harmful" DNA damage through precise mechanisms by the integrated functions of many proteins. ...In th …
To protect against such UV-induced DNA damage, living organisms nicely retain "DNA repair systems", which can ef …
NER and DDR: classical music with new instruments.
Sertic S, Pizzi S, Lazzaro F, Plevani P, Muzi-Falconi M. Sertic S, et al. Cell Cycle. 2012 Feb 15;11(4):668-74. doi: 10.4161/cc.11.4.19117. Cell Cycle. 2012. PMID: 22373527 Review.
Genomic insults by endogenous or exogenous sources activate the DNA damage response (DDR). After the recognition of damaged DNA by specific factors, repair mechanisms process the lesions, and a surveillance mechanism, known as DNA dama …
Genomic insults by endogenous or exogenous sources activate the DNA damage response (DDR). After the recognition of damaged …
The beneficial role of functional food components in mitigating ultraviolet-induced skin damage.
Morifuji M. Morifuji M. Exp Dermatol. 2019 Feb;28 Suppl 1:28-31. doi: 10.1111/exd.13825. Exp Dermatol. 2019. PMID: 30698876 Review.
Excessive exposure to ultraviolet (UV) radiation can chemically alter biological molecules and is one of the major environmental health risks with potential to damage the structure and function of the skin. ...Milk fermented with lactic acid bacteria has been …
Excessive exposure to ultraviolet (UV) radiation can chemically alter biological molecules and is one of the major environment …
Molecular mechanisms of ultraviolet radiation carcinogenesis.
Ananthaswamy HN, Pierceall WE. Ananthaswamy HN, et al. Photochem Photobiol. 1990 Dec;52(6):1119-36. doi: 10.1111/j.1751-1097.1990.tb08452.x. Photochem Photobiol. 1990. PMID: 2087500 Review.
UV radiation is a potent DNA damaging agent and a known inducer of skin cancer in experimental animals. ...The prevalence of skin cancer on sun-exposed body sites in individuals with the inherited disorder XP suggests that defective repair of UV …
UV radiation is a potent DNA damaging agent and a known inducer of skin cancer in experimental animals. ...The prevalen …
Hydrochlorothiazide Use and Risk of Nonmelanoma Skin Cancers: A Biological Plausibility Study.
Bigagli E, Cinci L, D'Ambrosio M, Nardini P, Portelli F, Colucci R, Lodovici M, Mugelli A, Luceri C. Bigagli E, et al. Oxid Med Cell Longev. 2021 Aug 14;2021:6655542. doi: 10.1155/2021/6655542. eCollection 2021. Oxid Med Cell Longev. 2021. PMID: 34434485 Free PMC article.
Under acute exposure, therapeutically relevant concentrations of HCTZ (70, 140, and 370 ng/mL) amplified UVA-induced double-strand breaks, oxidative DNA, and protein damage in HaCaT human keratinocytes, and this effect was associated to a defective activity o …
Under acute exposure, therapeutically relevant concentrations of HCTZ (70, 140, and 370 ng/mL) amplified UVA-induced double-strand breaks, o …
Repair of UV light-induced DNA damage and risk of cutaneous malignant melanoma.
Wei Q, Lee JE, Gershenwald JE, Ross MI, Mansfield PF, Strom SS, Wang LE, Guo Z, Qiao Y, Amos CI, Spitz MR, Duvic M. Wei Q, et al. J Natl Cancer Inst. 2003 Feb 19;95(4):308-15. doi: 10.1093/jnci/95.4.308. J Natl Cancer Inst. 2003. PMID: 12591987
Patients with xeroderma pigmentosum, a disease characterized by severe sensitivity to UV radiation and a defect in nucleotide excision repair, have a high incidence of CMM, which suggests that DNA repair capacity (DRC) plays a role in sunlight-i …
Patients with xeroderma pigmentosum, a disease characterized by severe sensitivity to UV radiation and a defect in nucleotide …
Evidence for persistent UV-induced DNA damage and altered DNA damage response in xeroderma pigmentosa patient corneas.
Akepogu J, Jakati S, Chaurasia S, Ramachandran C. Akepogu J, et al. Exp Eye Res. 2024 Jun;243:109901. doi: 10.1016/j.exer.2024.109901. Epub 2024 Apr 18. Exp Eye Res. 2024. PMID: 38641197
Here, we aimed to provide evidence for the accumulation of DNA damage and activation of DNA repair pathway proteins in the corneal cells of patients with XP. Corneal buttons of patients who underwent penetrating keratoplasty were stained to quantify …
Here, we aimed to provide evidence for the accumulation of DNA damage and activation of DNA repair pathway prote …
Ultraviolet-induced dna repair synthesis in lymphocytes from patients with actinic keratosis.
Lambert B, Ringborg U, Swanbeck G. Lambert B, et al. J Invest Dermatol. 1976 Nov;67(5):594-8. doi: 10.1111/1523-1747.ep12541694. J Invest Dermatol. 1976. PMID: 789782 Free article. Clinical Trial.
Extensive exposure to sunlight is considered as a contributing factor to the etiology of this tumor. Ultraviolet (UV) light of solar radiation induces structural damage in DNA, which may give rise to mutations and transformed cells if the damage …
Extensive exposure to sunlight is considered as a contributing factor to the etiology of this tumor. Ultraviolet (UV) light of solar …
The key role of UVA-light induced oxidative stress in human Xeroderma Pigmentosum Variant cells.
Moreno NC, Garcia CCM, Munford V, Rocha CRR, Pelegrini AL, Corradi C, Sarasin A, Menck CFM. Moreno NC, et al. Free Radic Biol Med. 2019 Feb 1;131:432-442. doi: 10.1016/j.freeradbiomed.2018.12.012. Epub 2018 Dec 13. Free Radic Biol Med. 2019. PMID: 30553972 Free article.
Xeroderma Pigmentosum Variant (XP-V) patients are defective in the DNA polymerase pol eta that promotes translesion synthesis after sunlight-induced DNA damage, implying in a clinical phenotype of increased frequency of skin cancer. ...DNA …
Xeroderma Pigmentosum Variant (XP-V) patients are defective in the DNA polymerase pol eta that promotes translesion synthesis …
Low extracellular pH inhibits nucleotide excision repair.
Fukuda T, Komaki Y, Mori Y, Ibuki Y. Fukuda T, et al. Mutat Res Genet Toxicol Environ Mutagen. 2021 Jul;867:503374. doi: 10.1016/j.mrgentox.2021.503374. Epub 2021 Jun 18. Mutat Res Genet Toxicol Environ Mutagen. 2021. PMID: 34266626
Nucleotide excision repair (NER) is the main pathway to repair bulky DNA damages including pyrimidine dimers, and the genetic dysregulation of NER associated proteins is well known to cause diseases such as cancer and neurological disorder. Other than …
Nucleotide excision repair (NER) is the main pathway to repair bulky DNA damages including pyrimidine dimers, an …
37 results