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Quoted phrase not found in phrase index: "Deficient excision of UV-induced pyrimidine dimers in DNA"
Page 1
Molecular cloning of the human DNA excision repair gene ERCC-6.
Troelstra C, Odijk H, de Wit J, Westerveld A, Thompson LH, Bootsma D, Hoeijmakers JH. Troelstra C, et al. Mol Cell Biol. 1990 Nov;10(11):5806-13. doi: 10.1128/mcb.10.11.5806-5813.1990. Mol Cell Biol. 1990. PMID: 2172786 Free PMC article.
The UV-sensitive, nucleotide excision repair-deficient Chinese hamster mutant cell line UV61 was used to identify and clone a correcting human gene, ERCC-6. UV61, belonging to rodent complementation group 6, is only moderately UV sensitive in comparison with mutant …
The UV-sensitive, nucleotide excision repair-deficient Chinese hamster mutant cell line UV61 was used to identify and clone a …
Identification and characterization of the rhp23(+) DNA repair gene in Schizosaccharomyces pombe.
Lombaerts M, Goeloe JI, den Dulk H, Brandsma JA, Brouwer J. Lombaerts M, et al. Biochem Biophys Res Commun. 2000 Feb 5;268(1):210-5. doi: 10.1006/bbrc.2000.2100. Biochem Biophys Res Commun. 2000. PMID: 10652237
We have identified rhp23(+), the ortholog of the Saccharomyces cerevisiae RAD23 and human HHR23A and HHR23B genes, in Schizosaccharomyces pombe and examined its role in cell survival and DNA repair. In S. pombe two repair mechanisms are operative on UV-induced
We have identified rhp23(+), the ortholog of the Saccharomyces cerevisiae RAD23 and human HHR23A and HHR23B genes, in Schizosaccharomyces po …
Requirement for functional DNA polymerase eta in genome-wide repair of UV-induced DNA damage during S phase.
Auclair Y, Rouget R, Belisle JM, Costantino S, Drobetsky EA. Auclair Y, et al. DNA Repair (Amst). 2010 Jul 1;9(7):754-64. doi: 10.1016/j.dnarep.2010.03.013. Epub 2010 Apr 24. DNA Repair (Amst). 2010. PMID: 20457011
These phenotypes are clearly attributable to germline mutations in POLH, encoding DNA polymerase eta (poleta) normally required for accurate translesion DNA synthesis (TLS) past UV-induced cyclobutane pyrimidine dimers. ...We now present …
These phenotypes are clearly attributable to germline mutations in POLH, encoding DNA polymerase eta (poleta) normally required for a …
Slowly progressing nucleotide excision repair in trichothiodystrophy group A patient fibroblasts.
Theil AF, Nonnekens J, Wijgers N, Vermeulen W, Giglia-Mari G. Theil AF, et al. Mol Cell Biol. 2011 Sep;31(17):3630-8. doi: 10.1128/MCB.01462-10. Epub 2011 Jul 5. Mol Cell Biol. 2011. PMID: 21730288 Free PMC article.
TFIIH is an essential transcription initiation factor that is also pivotal for nucleotide excision repair (NER). Photosensitive TTD is explained by deficient NER, dedicated to removing UV-induced DNA lesions. ...TTD-A patients display a relative …
TFIIH is an essential transcription initiation factor that is also pivotal for nucleotide excision repair (NER). Photosensitive TTD i …
Comparative study of nucleotide excision repair defects between XPD-mutated fibroblasts derived from trichothiodystrophy and xeroderma pigmentosum patients.
Nishiwaki T, Kobayashi N, Iwamoto T, Yamamoto A, Sugiura S, Liu YC, Sarasin A, Okahashi Y, Hirano M, Ueno S, Mori T. Nishiwaki T, et al. DNA Repair (Amst). 2008 Dec 1;7(12):1990-8. doi: 10.1016/j.dnarep.2008.08.009. Epub 2008 Oct 10. DNA Repair (Amst). 2008. PMID: 18817897
The 3 XP-D cell strains examined were similarly deficient in repairing UV-induced cyclobutane pyrimidine dimers (CPDs) and (6-4) photoproducts (6-4PPs) from genomic DNA. ...All XP-D cell strains were normal in their concentrations of TFII …
The 3 XP-D cell strains examined were similarly deficient in repairing UV-induced cyclobutane pyrimidine dime
Prevention of ultraviolet radiation-induced immunosuppression by (-)-epigallocatechin-3-gallate in mice is mediated through interleukin 12-dependent DNA repair.
Meeran SM, Mantena SK, Katiyar SK. Meeran SM, et al. Clin Cancer Res. 2006 Apr 1;12(7 Pt 1):2272-80. doi: 10.1158/1078-0432.CCR-05-2672. Clin Cancer Res. 2006. PMID: 16609044
The effect of EGCG was determined on UV-induced suppression of contact hypersensitivity and UV-induced DNA damage in the form of cyclobutane pyrimidine dimers (CPD) in mice and XPA-deficient cells using immunohistochemistry …
The effect of EGCG was determined on UV-induced suppression of contact hypersensitivity and UV-induced DNA
DNA polymerase zeta cooperates with polymerases kappa and iota in translesion DNA synthesis across pyrimidine photodimers in cells from XPV patients.
Ziv O, Geacintov N, Nakajima S, Yasui A, Livneh Z. Ziv O, et al. Proc Natl Acad Sci U S A. 2009 Jul 14;106(28):11552-7. doi: 10.1073/pnas.0812548106. Epub 2009 Jun 29. Proc Natl Acad Sci U S A. 2009. PMID: 19564618 Free PMC article.
Human cells tolerate UV-induced cyclobutane pyrimidine dimers (CPD) by translesion DNA synthesis (TLS), carried out by DNA polymerase eta, the POLH gene product. ...Moreover, DNA polymerases zeta and kappa, but not iota, protect XP …
Human cells tolerate UV-induced cyclobutane pyrimidine dimers (CPD) by translesion DNA synthesis (TLS), c …
Drosophila p53 is required to increase the levels of the dKDM4B demethylase after UV-induced DNA damage to demethylate histone H3 lysine 9.
Palomera-Sanchez Z, Bucio-Mendez A, Valadez-Graham V, Reynaud E, Zurita M. Palomera-Sanchez Z, et al. J Biol Chem. 2010 Oct 8;285(41):31370-9. doi: 10.1074/jbc.M110.128462. Epub 2010 Jul 30. J Biol Chem. 2010. PMID: 20675387 Free PMC article.
Chromatin undergoes a variety of changes in response to UV-induced DNA damage, including histone acetylation. In human and Drosophila cells, this response is affected by mutations in the tumor suppressor p53. ...Furthermore, heterozygous mutants for the dKdm4 …
Chromatin undergoes a variety of changes in response to UV-induced DNA damage, including histone acetylation. In human …
Human cells deficient in p53 regulated p21(waf1/cip1) expression exhibit normal nucleotide excision repair of UV-induced DNA damage.
Wani MA, Wani G, Yao J, Zhu Q, Wani AA. Wani MA, et al. Carcinogenesis. 2002 Mar;23(3):403-10. doi: 10.1093/carcin/23.3.403. Carcinogenesis. 2002. PMID: 11895854
Following 20 J/m(2) UV, all the three cell lines showed rapid increase in p53 protein but the accompanying increase in the expression of its downstream target protein p21 could only be seen in p21+/+ and p21+/- cells and not in p21-/- cells. Nevertheless, an absence of detectable …
Following 20 J/m(2) UV, all the three cell lines showed rapid increase in p53 protein but the accompanying increase in the expression of its …
Persistent DNA damage induced by ultraviolet light inhibits p21waf1 and bax expression: implications for DNA repair, UV sensitivity and the induction of apoptosis.
McKay BC, Ljungman M, Rainbow AJ. McKay BC, et al. Oncogene. 1998 Aug 6;17(5):545-55. doi: 10.1038/sj.onc.1201963. Oncogene. 1998. PMID: 9704920
Ultraviolet light (UV) induced DNA lesions efficiently block transcript elongation and induce the p53 response. Although p53 contributes to transcriptional activation of the p21waf1 and bax genes, accumulation of these proteins requires that these genes are f …
Ultraviolet light (UV) induced DNA lesions efficiently block transcript elongation and induce the p53 response. Althoug …
25 results