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Results by year

Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1950 1
1952 1
1953 8
1954 10
1955 15
1956 9
1957 9
1958 19
1959 8
1962 3
1963 3
1964 7
1965 75
1966 108
1967 157
1968 186
1969 240
1970 344
1971 375
1972 433
1973 499
1974 724
1975 680
1976 569
1977 523
1978 501
1979 559
1980 516
1981 498
1982 602
1983 577
1984 660
1985 644
1986 706
1987 666
1988 749
1989 782
1990 877
1991 859
1992 910
1993 989
1994 1081
1995 1081
1996 1177
1997 1348
1998 1457
1999 1545
2000 1557
2001 1716
2002 1890
2003 2114
2004 2427
2005 2612
2006 2901
2007 3011
2008 3117
2009 3448
2010 3653
2011 3916
2012 4359
2013 4848
2014 4948
2015 4885
2016 5009
2017 5256
2018 5624
2019 6014
2020 6448
2021 6416
2022 6409
2023 5877
2024 2534

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110,284 results

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Page 1
Biases in reporting of adverse effects in clinical trials, and potential impact on safety assessments in systematic reviews and therapy guidelines.
Westergren T, Narum S, Klemp M. Westergren T, et al. Basic Clin Pharmacol Toxicol. 2022 Dec;131(6):465-473. doi: 10.1111/bcpt.13791. Epub 2022 Oct 5. Basic Clin Pharmacol Toxicol. 2022. PMID: 36125975 Free PMC article. Review.
OBJECTIVES: The objectives of this work are to analyse risk of gastrointestinal bleeding in systemic corticosteroid trials and to assess adverse effects reporting in a fluoxetine trial in depression (Treatment for Adolescents With Depression Study [TADS]) and …
OBJECTIVES: The objectives of this work are to analyse risk of gastrointestinal bleeding in systemic corticosteroid trials and to assess adv …
Acupuncture for depression: a critique of the evidence base.
Schroer S, Adamson J. Schroer S, et al. CNS Neurosci Ther. 2011 Oct;17(5):398-410. doi: 10.1111/j.1755-5949.2010.00159.x. Epub 2010 Nov 21. CNS Neurosci Ther. 2011. PMID: 21091639 Free PMC article. Review.
DISCUSSION: The review identified a number of study limitations. (i) PATIENTS: majority of trial reports have not described a rationale for the selection of patients or inclusion/exclusion criteria. ...Existing evaluations may however be useful for guiding decisions about …
DISCUSSION: The review identified a number of study limitations. (i) PATIENTS: majority of trial reports have not described a rationa …
The conundrum of depression clinical trials: one size does not fit all.
Khan A, Mar KF, Brown WA. Khan A, et al. Int Clin Psychopharmacol. 2018 Sep;33(5):239-248. doi: 10.1097/YIC.0000000000000229. Int Clin Psychopharmacol. 2018. PMID: 29939890 Free PMC article. Review.
In addition, we describe the lack of precision in the depression outcome measurements for the past 40 years and show how these measures contrast with those used in clinical trials of other chronic diseases, which use simpler outcome measures. Finally, we describe th …
In addition, we describe the lack of precision in the depression outcome measurements for the past 40 years and show how these measur …
Electroconvulsive therapy in 1985--a review.
Varghese FT, Singh BS. Varghese FT, et al. Med J Aust. 1985 Sep 2;143(5):192-6. doi: 10.5694/j.1326-5377.1985.tb122912.x. Med J Aust. 1985. PMID: 2863740 Review.
Electroconvulsive therapy (ECT) has recently been re-examined in randomized, double-blind controlled trials. Although a variable placebo influence has been demonstrated, the effectiveness of ECT in severe depression is now well established. ...
Electroconvulsive therapy (ECT) has recently been re-examined in randomized, double-blind controlled trials. Although a variable plac …
Effectiveness of social support-based interventions in preventing depression in people without clinical depression: A systematic review and meta-analysis of randomized controlled trials.
Campos-Paíno H, Moreno-Peral P, Gómez-Gómez I, Conejo-Cerón S, Galán S, Reyes-Martín S, Bellón JÁ. Campos-Paíno H, et al. Int J Soc Psychiatry. 2023 Mar;69(2):253-266. doi: 10.1177/00207640221134232. Epub 2022 Nov 23. Int J Soc Psychiatry. 2023. PMID: 36419332 Review.
BACKGROUND: The evidence available on the association between social support and prevention of depression has been basically obtained from observational studies. AIM: We evaluated the effectiveness of social support-based interventions for the prevention of depression
BACKGROUND: The evidence available on the association between social support and prevention of depression has been basically obtained …
Comparative clinical trials in psychotherapy: Have large effects been replicated?
Frost ND, Baskin TW, Wampold BE. Frost ND, et al. Epidemiol Psychiatr Sci. 2020 May 15;29:e128. doi: 10.1017/S2045796020000402. Epidemiol Psychiatr Sci. 2020. PMID: 32410720 Free PMC article. Review.
AIMS: The purpose of this review is to examine the replication attempts of psychotherapy clinical trials for depression and anxiety. We focus specifically on replications of trials that exhibit large differences between psychotherapies. ...Trials that exhibited larg …
AIMS: The purpose of this review is to examine the replication attempts of psychotherapy clinical trials for depression and an …
Study protocol for pragmatic trials of Internet-delivered guided and unguided cognitive behavior therapy for treating depression and anxiety in university students of two Latin American countries: the Yo Puedo Sentirme Bien study.
Benjet C, Kessler RC, Kazdin AE, Cuijpers P, Albor Y, Carrasco Tapias N, Contreras-Ibáñez CC, Durán González MS, Gildea SM, González N, Guerrero López JB, Luedtke A, Medina-Mora ME, Palacios J, Richards D, Salamanca-Sanabria A, Sampson NA. Benjet C, et al. Trials. 2022 Jun 2;23(1):450. doi: 10.1186/s13063-022-06255-3. Trials. 2022. PMID: 35658942 Free PMC article.
We aim to evaluate the effects of expanding treatment using scalable and inexpensive Internet-delivered transdiagnostic cognitive behavioral therapy (iCBT) among college students with symptoms of MDD and/or GAD in two LMICs in Latin America (Colombia and Mexico) and to investigat …
We aim to evaluate the effects of expanding treatment using scalable and inexpensive Internet-delivered transdiagnostic cognitive behavioral …
Forks in the road: Definitions of response, remission, recovery, and other dichotomized outcomes in randomized controlled trials for adolescent depression. A scoping review.
Courtney DB, Watson P, Chan BW, Bennett K, Krause KR, Offringa M, Butcher NJ, Monga S, Neprily K, Zentner T, Rodak T, Szatmari P. Courtney DB, et al. Depress Anxiety. 2021 Nov;38(11):1152-1168. doi: 10.1002/da.23200. Epub 2021 Jul 26. Depress Anxiety. 2021. PMID: 34312952 Review.
BACKGROUND: Definitions of dichotomous outcome terms, such as "response," "remission," and "recovery" are central to the design, interpretation, and clinical application of randomized controlled trials of adolescent depression interventions. Accordingly, this …
BACKGROUND: Definitions of dichotomous outcome terms, such as "response," "remission," and "recovery" are central to the design, interpretat …
The challenge of treatment in bipolar depression: evidence from clinical guidelines, treatment recommendations and complex treatment situations.
Köhler S, Gaus S, Bschor T. Köhler S, et al. Pharmacopsychiatry. 2014 Mar;47(2):53-9. doi: 10.1055/s-0033-1364004. Epub 2014 Feb 18. Pharmacopsychiatry. 2014. PMID: 24549861 Review.
Bipolar depression and its clinical presentation is a frequent but complex psychiatric disease. Despite the high prevalence and the clinical and economic relevance of bipolar depression, few treatments are proven to be highly and consistently effective …
Bipolar depression and its clinical presentation is a frequent but complex psychiatric disease. Despite the high prevalence an …
Psychotherapy for bipolar depression: a phase-specific treatment strategy?
Swartz HA, Frank E. Swartz HA, et al. Bipolar Disord. 2001 Feb;3(1):11-22. doi: 10.1034/j.1399-5618.2001.030102.x. Bipolar Disord. 2001. PMID: 11256459 Review.
OBJECTIVES: The depressive phase of bipolar disorder is particularly difficult to treat. Pharmacologic strategies for bipolar depression are often inadequate. We therefore review the literature on the role of psychotherapy as an adjunct to medication in the treatment of bi …
OBJECTIVES: The depressive phase of bipolar disorder is particularly difficult to treat. Pharmacologic strategies for bipolar depression
110,284 results
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