Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My NCBI Filters

Results by year

Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1985 1
1986 2
1988 2
1989 1
1990 4
1991 6
1992 2
1993 2
1994 2
1995 1
1996 5
1997 3
1998 5
1999 6
2000 4
2001 6
2002 6
2003 13
2004 10
2005 12
2006 19
2007 15
2008 16
2009 19
2010 15
2011 24
2012 48
2013 40
2014 61
2015 67
2016 68
2017 56
2018 58
2019 38
2020 31
2021 42
2022 35
2023 36
2024 12

Text availability

Article attribute

Article type

Publication date

Search Results

672 results

Results by year

Filters applied: . Clear all
Page 1
Designer drugs: mechanism of action and adverse effects.
Luethi D, Liechti ME. Luethi D, et al. Arch Toxicol. 2020 Apr;94(4):1085-1133. doi: 10.1007/s00204-020-02693-7. Epub 2020 Apr 6. Arch Toxicol. 2020. PMID: 32249347 Free PMC article. Review.
A troubling designer drug.
Kozlowski M. Kozlowski M. Lab Anim (NY). 2022 Jan;51(1):3. doi: 10.1038/s41684-021-00895-9. Lab Anim (NY). 2022. PMID: 34949842 No abstract available.
Anticipating designer drug-resistant cancer cells.
Frangione ML, Lockhart JH, Morton DT, Pava LM, Blanck G. Frangione ML, et al. Drug Discov Today. 2015 Jul;20(7):790-3. doi: 10.1016/j.drudis.2015.02.005. Epub 2015 Feb 16. Drug Discov Today. 2015. PMID: 25697478 Review.
Considering the knowledge base of cancer signaling pathways, mechanisms of designer drug resistance should be anticipated, and early clinical trials could be designed to include arms that combine new drugs specifically with currently US Food and Drug Administration …
Considering the knowledge base of cancer signaling pathways, mechanisms of designer drug resistance should be anticipated, and …
Research Status of New Designer Drug Methcathinone in Forensic Toxicology.
Deng YF, Liu L, Yang ZX, Liang M. Deng YF, et al. Fa Yi Xue Za Zhi. 2018 Jun;34(6):611-616. doi: 10.12116/j.issn.1004-5619.2018.06.007. Epub 2018 Dec 25. Fa Yi Xue Za Zhi. 2018. PMID: 30896098 Free article. Review. Chinese, English.
Methcathinone, a new cathinone designer drug, which is structurally similar to amphetamine analogs, is a central nervous stimulant. ...
Methcathinone, a new cathinone designer drug, which is structurally similar to amphetamine analogs, is a central nervous stimu …
[The development from drug to designer drug].
Askaa B, Horwitz H, Wøien VA, Høgberg LC, Jürgens G. Askaa B, et al. Ugeskr Laeger. 2014 Oct 13;176(42):V04140231. Ugeskr Laeger. 2014. PMID: 25316367 Free article. Review. Danish.
Designer Drug Detective Work.
Gebel Berg E. Gebel Berg E. ACS Cent Sci. 2016 Jun 22;2(6):363-6. doi: 10.1021/acscentsci.6b00160. Epub 2016 Jun 10. ACS Cent Sci. 2016. PMID: 27413778 Free PMC article. No abstract available.
Chemogenetics revealed: DREADD occupancy and activation via converted clozapine.
Gomez JL, Bonaventura J, Lesniak W, Mathews WB, Sysa-Shah P, Rodriguez LA, Ellis RJ, Richie CT, Harvey BK, Dannals RF, Pomper MG, Bonci A, Michaelides M. Gomez JL, et al. Science. 2017 Aug 4;357(6350):503-507. doi: 10.1126/science.aan2475. Science. 2017. PMID: 28774929 Free PMC article.
DREADD technology posits the use of "designer receptors," which are exclusively activated by the "designer drug" clozapine N-oxide (CNO). Nevertheless, the in vivo mechanism of action of CNO at DREADDs has never been confirmed. ...
DREADD technology posits the use of "designer receptors," which are exclusively activated by the "designer drug" clozapine N-o …
672 results