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Year Number of Results
1988 1
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1991 36
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1995 31
1996 25
1997 44
1998 26
1999 32
2000 43
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2002 46
2003 46
2004 67
2005 79
2006 108
2007 110
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2010 190
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2024 438

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9,602 results

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Page 1
Dexmedetomidine: present and future directions.
Lee S. Lee S. Korean J Anesthesiol. 2019 Aug;72(4):323-330. doi: 10.4097/kja.19259. Epub 2019 Jun 21. Korean J Anesthesiol. 2019. PMID: 31220910 Free PMC article. Review.
Dexmedetomidine may produce less delirium than other sedatives or even prevent delirium. ...Most adverse events associated with dexmedetomidine occur during or shortly after a loading infusion. There are some case reports of dexmedetomidine-related cardiac ar …
Dexmedetomidine may produce less delirium than other sedatives or even prevent delirium. ...Most adverse events associated with de …
Dexmedetomidine as an Adjuvant in Peripheral Nerve Block.
Chen Z, Liu Z, Feng C, Jin Y, Zhao X. Chen Z, et al. Drug Des Devel Ther. 2023 May 17;17:1463-1484. doi: 10.2147/DDDT.S405294. eCollection 2023. Drug Des Devel Ther. 2023. PMID: 37220544 Free PMC article. Review.
Therefore, the risk-benefit ratio must be evaluated when using these drugs as adjuvants. This review explains the pharmacology and mechanism of dexmedetomidine, the effect of dexmedetomidine on various peripheral nerve block as an adjuvant, and compare it with other …
Therefore, the risk-benefit ratio must be evaluated when using these drugs as adjuvants. This review explains the pharmacology and mechanism …
Dexmedetomidine: A Review of Its Use for Sedation in the Intensive Care Setting.
Keating GM. Keating GM. Drugs. 2015 Jul;75(10):1119-30. doi: 10.1007/s40265-015-0419-5. Drugs. 2015. PMID: 26063213 Review.
Dexmedetomidine (Dexdor()) is a highly selective alpha2-adrenoceptor agonist. ...In conclusion, dexmedetomidine is an important option for sedation in the intensive care setting....
Dexmedetomidine (Dexdor()) is a highly selective alpha2-adrenoceptor agonist. ...In conclusion, dexmedetomidine is an importan …
Intranasal dexmedetomidine in pediatrics: update of current knowledge.
Mondardini MC, Amigoni A, Cortellazzi P, Di Palma A, Navarra C, Picardo SG, Puzzutiello R, Rinaldi L, Vitale F, Zito Marinosci G, Conti G. Mondardini MC, et al. Minerva Anestesiol. 2019 Dec;85(12):1334-1345. doi: 10.23736/S0375-9393.19.13820-5. Epub 2019 Oct 14. Minerva Anestesiol. 2019. PMID: 31630510 Free article. Review.
Intranasal dexmedetomidine, although still off-label, recently boasted an increasing consensus for different uses, namely, in diagnostic non-painful procedures, in painful procedures and in surgical premedication. ...This article aims to provide a comprehensive literature …
Intranasal dexmedetomidine, although still off-label, recently boasted an increasing consensus for different uses, namely, in diagnos …
Dexmedetomidine: current role in anesthesia and intensive care.
Afonso J, Reis F. Afonso J, et al. Rev Bras Anestesiol. 2012 Jan-Feb;62(1):118-33. doi: 10.1016/S0034-7094(12)70110-1. Rev Bras Anestesiol. 2012. PMID: 22248773 Free article. Review.
BACKGROUND AND OBJECTIVES: To update and review the application of dexmedetomidine in anesthesia and intensive care. This study is a comprehensive review of clinical uses, pharmacology, pharmacokinetics, mechanism of action and adverse effects of dexmedetomidine. .. …
BACKGROUND AND OBJECTIVES: To update and review the application of dexmedetomidine in anesthesia and intensive care. This study is a …
Dexmedetomidine versus Midazolam in Procedural Sedation. A Systematic Review of Efficacy and Safety.
Barends CR, Absalom A, van Minnen B, Vissink A, Visser A. Barends CR, et al. PLoS One. 2017 Jan 20;12(1):e0169525. doi: 10.1371/journal.pone.0169525. eCollection 2017. PLoS One. 2017. PMID: 28107373 Free PMC article. Review.
Patients receiving dexmedetomidine experienced less pain and had lower analgesic requirements. ...Dexmedetomidine provides more comfort during the procedure for the patient and clinician. ...
Patients receiving dexmedetomidine experienced less pain and had lower analgesic requirements. ...Dexmedetomidine provides mor …
Dexmedetomidine vs midazolam or propofol for sedation during prolonged mechanical ventilation: two randomized controlled trials.
Jakob SM, Ruokonen E, Grounds RM, Sarapohja T, Garratt C, Pocock SJ, Bratty JR, Takala J; Dexmedetomidine for Long-Term Sedation Investigators. Jakob SM, et al. JAMA. 2012 Mar 21;307(11):1151-60. doi: 10.1001/jama.2012.304. JAMA. 2012. PMID: 22436955 Clinical Trial.
Time at target sedation was analyzed in per-protocol population (midazolam, n = 233, vs dexmedetomidine, n = 227; propofol, n = 214, vs dexmedetomidine, n = 223). RESULTS: Dexmedetomidine/midazolam ratio in time at target sedation was 1.07 (95% CI, 0.97-1.18) …
Time at target sedation was analyzed in per-protocol population (midazolam, n = 233, vs dexmedetomidine, n = 227; propofol, n = 214, …
Dexmedetomidine: a magic bullet on its way into palliative care-a narrative review and practice recommendations.
Gaertner J, Fusi-Schmidhauser T. Gaertner J, et al. Ann Palliat Med. 2022 Apr;11(4):1491-1504. doi: 10.21037/apm-21-1989. Epub 2022 Apr 6. Ann Palliat Med. 2022. PMID: 35400162 Free article. Review.
BACKGROUND AND OBJECTIVE: Dexmedetomidine is a potent adrenergic alpha-2 receptor agonist. It was first approved for sedation for mechanically ventilated patients. ...Since the drug has a main hepatic metabolism, dose reduction is mandatory in patients with hepatic impairm …
BACKGROUND AND OBJECTIVE: Dexmedetomidine is a potent adrenergic alpha-2 receptor agonist. It was first approved for sedation for mec …
Dexmedetomidine and Perioperative Arrhythmias.
Duan S, Zhou S. Duan S, et al. J Cardiothorac Vasc Anesth. 2024 May;38(5):1221-1227. doi: 10.1053/j.jvca.2024.01.006. Epub 2024 Jan 10. J Cardiothorac Vasc Anesth. 2024. PMID: 38443205 Review.
Several studies have indicated that dexmedetomidine may have a potential role in preventing and treating perioperative tachyarrhythmias. However, the specific effect and mechanism of action of dexmedetomidine in this context remain unclear. Dexmedetomidine is …
Several studies have indicated that dexmedetomidine may have a potential role in preventing and treating perioperative tachyarrhythmi …
Dexmedetomidine and perioperative analgesia in children.
Eizaga Rebollar R, García Palacios MV, Fernández Riobó MC, Torres Morera LM. Eizaga Rebollar R, et al. Rev Esp Anestesiol Reanim (Engl Ed). 2022 Oct;69(8):487-492. doi: 10.1016/j.redare.2022.08.003. Epub 2022 Sep 10. Rev Esp Anestesiol Reanim (Engl Ed). 2022. PMID: 36100555 Review.
Dexmedetomidine (DEX) is an anaesthetic agent that mimics natural deep sleep and produces minimal cardiorespiratory depression. ...
Dexmedetomidine (DEX) is an anaesthetic agent that mimics natural deep sleep and produces minimal cardiorespiratory depression. ...
9,602 results