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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1989 1
1991 2
1993 1
1995 3
1997 1
1998 1
1999 2
2000 1
2001 6
2002 4
2003 3
2004 4
2005 8
2006 9
2007 10
2008 18
2009 22
2010 23
2011 27
2012 25
2013 36
2014 46
2015 70
2016 59
2017 97
2018 82
2019 105
2020 117
2021 146
2022 156
2023 164
2024 61

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960 results

Results by year

Filters applied: Meta-Analysis, Review, Systematic Review, in the last 10 years. Clear all
Page 1
Dexmedetomidine: present and future directions.
Lee S. Lee S. Korean J Anesthesiol. 2019 Aug;72(4):323-330. doi: 10.4097/kja.19259. Epub 2019 Jun 21. Korean J Anesthesiol. 2019. PMID: 31220910 Free PMC article. Review.
Dexmedetomidine may produce less delirium than other sedatives or even prevent delirium. ...Most adverse events associated with dexmedetomidine occur during or shortly after a loading infusion. There are some case reports of dexmedetomidine-related cardiac ar …
Dexmedetomidine may produce less delirium than other sedatives or even prevent delirium. ...Most adverse events associated with de …
Clinical Pharmacokinetics and Pharmacodynamics of Dexmedetomidine.
Weerink MAS, Struys MMRF, Hannivoort LN, Barends CRM, Absalom AR, Colin P. Weerink MAS, et al. Clin Pharmacokinet. 2017 Aug;56(8):893-913. doi: 10.1007/s40262-017-0507-7. Clin Pharmacokinet. 2017. PMID: 28105598 Free PMC article. Review.
Dexmedetomidine is rapidly distributed and is mainly hepatically metabolized into inactive metabolites by glucuronidation and hydroxylation. ...Procedural sedation with dexmedetomidine was additionally approved by the US Food and Drug Administration in 2003 and d …
Dexmedetomidine is rapidly distributed and is mainly hepatically metabolized into inactive metabolites by glucuronidation and hydroxy …
Dexmedetomidine.
[No authors listed] [No authors listed] 2023 Feb 15. Drugs and Lactation Database (LactMed®) [Internet]. Bethesda (MD): National Institute of Child Health and Human Development; 2006–. 2023 Feb 15. Drugs and Lactation Database (LactMed®) [Internet]. Bethesda (MD): National Institute of Child Health and Human Development; 2006–. PMID: 29999945 Free Books & Documents. Review.
Limited data indicate that very small amounts of dexmedetomidine are excreted into breastmilk for 4 to 6 hours after the end of an intravenous infusion. ...Because of the low dose in milk and its poor oral bioavailability, dexmedetomidine would not be expected to ca …
Limited data indicate that very small amounts of dexmedetomidine are excreted into breastmilk for 4 to 6 hours after the end of an in …
Dexmedetomidine in the pediatric population: a review.
Plambech MZ, Afshari A. Plambech MZ, et al. Minerva Anestesiol. 2015 Mar;81(3):320-32. Epub 2014 May 14. Minerva Anestesiol. 2015. PMID: 24824958 Free article. Review.
Dexmedetomidine is also used intravenously at different intensive care units with the purpose of sedation of children. ...Finally, we provide the readers with guidance on how to apply and dose dexmedetomidine for pediatric sedation and for other indications....
Dexmedetomidine is also used intravenously at different intensive care units with the purpose of sedation of children. ...Finally, we …
Could dexmedetomidine be repurposed as a glymphatic enhancer?
Persson NDÅ, Uusalo P, Nedergaard M, Lohela TJ, Lilius TO. Persson NDÅ, et al. Trends Pharmacol Sci. 2022 Dec;43(12):1030-1040. doi: 10.1016/j.tips.2022.09.007. Epub 2022 Oct 21. Trends Pharmacol Sci. 2022. PMID: 36280451 Free article. Review.
By contrast, sleep deprivation reduces glymphatic clearance and leads to intracerebral accumulation of metabolic waste, suggesting an underlying mechanism linking sleep disturbances with neurodegenerative diseases. The selective alpha(2)-adrenergic agonist dexmedetomidine …
By contrast, sleep deprivation reduces glymphatic clearance and leads to intracerebral accumulation of metabolic waste, suggesting an underl …
Intranasal dexmedetomidine in pediatrics: update of current knowledge.
Mondardini MC, Amigoni A, Cortellazzi P, Di Palma A, Navarra C, Picardo SG, Puzzutiello R, Rinaldi L, Vitale F, Zito Marinosci G, Conti G. Mondardini MC, et al. Minerva Anestesiol. 2019 Dec;85(12):1334-1345. doi: 10.23736/S0375-9393.19.13820-5. Epub 2019 Oct 14. Minerva Anestesiol. 2019. PMID: 31630510 Free article. Review.
Intranasal dexmedetomidine, although still off-label, recently boasted an increasing consensus for different uses, namely, in diagnostic non-painful procedures, in painful procedures and in surgical premedication. ...This article aims to provide a comprehensive literature …
Intranasal dexmedetomidine, although still off-label, recently boasted an increasing consensus for different uses, namely, in diagnos …
The neuroprotective effect of dexmedetomidine and its mechanism.
Hu Y, Zhou H, Zhang H, Sui Y, Zhang Z, Zou Y, Li K, Zhao Y, Xie J, Zhang L. Hu Y, et al. Front Pharmacol. 2022 Sep 20;13:965661. doi: 10.3389/fphar.2022.965661. eCollection 2022. Front Pharmacol. 2022. PMID: 36204225 Free PMC article. Review.
Dexmedetomidine (DEX) is a highly selective alpha2 receptor agonist that is routinely used in the clinic for sedation and anesthesia. ...
Dexmedetomidine (DEX) is a highly selective alpha2 receptor agonist that is routinely used in the clinic for sedation and anesthesia. …
Dexmedetomidine: A Review of Its Use for Sedation in the Intensive Care Setting.
Keating GM. Keating GM. Drugs. 2015 Jul;75(10):1119-30. doi: 10.1007/s40265-015-0419-5. Drugs. 2015. PMID: 26063213 Review.
Dexmedetomidine (Dexdor()) is a highly selective alpha2-adrenoceptor agonist. ...In conclusion, dexmedetomidine is an important option for sedation in the intensive care setting....
Dexmedetomidine (Dexdor()) is a highly selective alpha2-adrenoceptor agonist. ...In conclusion, dexmedetomidine is an importan …
Dexmedetomidine in Enhanced Recovery After Surgery (ERAS) Protocols for Postoperative Pain.
Kaye AD, Chernobylsky DJ, Thakur P, Siddaiah H, Kaye RJ, Eng LK, Harbell MW, Lajaunie J, Cornett EM. Kaye AD, et al. Curr Pain Headache Rep. 2020 Apr 2;24(5):21. doi: 10.1007/s11916-020-00853-z. Curr Pain Headache Rep. 2020. PMID: 32240402 Free PMC article. Review.
Dexmedetomidine can be used as an adjuvant in epidurals with local anesthetic sparing effects. ...An in-depth review of the use of dexmedetomidine in ERAS protocols is presented for clinical anesthesiologists....
Dexmedetomidine can be used as an adjuvant in epidurals with local anesthetic sparing effects. ...An in-depth review of the use of …
Dexmedetomidine for adult cardiac surgery: a systematic review, meta-analysis and trial sequential analysis.
Poon WH, Ling RR, Yang IX, Luo H, Kofidis T, MacLaren G, Tham C, Teoh KLK, Ramanathan K. Poon WH, et al. Anaesthesia. 2023 Mar;78(3):371-380. doi: 10.1111/anae.15947. Epub 2022 Dec 19. Anaesthesia. 2023. PMID: 36535747 Free article. Review.
The effects of dexmedetomidine in adults undergoing cardiac surgery are inconsistent. ...Adjustments for possible false data reduced the mean (95%CI) reduction in duration of intensive care and tracheal intubation by dexmedetomidine to 3.6 (1.8-5.4) h and 0.8 (0.2-1 …
The effects of dexmedetomidine in adults undergoing cardiac surgery are inconsistent. ...Adjustments for possible false data reduced …
960 results