TLR4-dependant immune response, but not hepatitis B virus reactivation, is important in radiation-induced liver disease of liver cancer radiotherapy.
Wu ZF, Zhou XH, Hu YW, Zhou LY, Gao YB, Peng XH, Yang XH, Zhang JY, Hu Y, Zeng ZC.
Wu ZF, et al.
Cancer Immunol Immunother. 2014 Mar;63(3):235-45. doi: 10.1007/s00262-013-1504-9. Epub 2013 Dec 15.
Cancer Immunol Immunother. 2014.
PMID: 24337704
Free PMC article.
HBV reactivation, TLR4 expression, and severity of RILDs were studied in both mouse and human. More HBV reactivation, without significant RILD, was observed in irradiated versus unirradiated TLR4(-) mice. RILD scores of TLR4(+) mice were higher than TLR4(-) mice. .. …
HBV reactivation, TLR4 expression, and severity of RILDs were studied in both mouse and human. More HBV reactivation, without significant RI …