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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1965 1
1966 1
1967 1
1968 3
1969 1
1970 2
1971 3
1972 5
1973 7
1974 9
1975 58
1976 60
1977 51
1978 65
1979 57
1980 77
1981 93
1982 91
1983 121
1984 141
1985 144
1986 140
1987 170
1988 198
1989 197
1990 250
1991 290
1992 272
1993 305
1994 398
1995 404
1996 475
1997 525
1998 551
1999 609
2000 639
2001 655
2002 770
2003 785
2004 854
2005 906
2006 923
2007 977
2008 999
2009 1215
2010 1241
2011 1381
2012 1494
2013 1604
2014 1900
2015 1974
2016 2158
2017 2302
2018 2438
2019 2664
2020 2748
2021 2832
2022 2720
2023 2487
2024 1058

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40,387 results

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Quoted phrase not found in phrase index: "Disorder by Site"
Page 1
Human hallucinogen research: guidelines for safety.
Johnson M, Richards W, Griffiths R. Johnson M, et al. J Psychopharmacol. 2008 Aug;22(6):603-20. doi: 10.1177/0269881108093587. Epub 2008 Jul 1. J Psychopharmacol. 2008. PMID: 18593734 Free PMC article. Review.
Safeguards against these risks include the exclusion of volunteers with personal or family history of psychotic disorders or other severe psychiatric disorders, establishing trust and rapport between session monitors and volunteer before the session, careful volunte …
Safeguards against these risks include the exclusion of volunteers with personal or family history of psychotic disorders or other se …
Efficacy of neurostimulation across mental disorders: systematic review and meta-analysis of 208 randomized controlled trials.
Hyde J, Carr H, Kelley N, Seneviratne R, Reed C, Parlatini V, Garner M, Solmi M, Rosson S, Cortese S, Brandt V. Hyde J, et al. Mol Psychiatry. 2022 Jun;27(6):2709-2719. doi: 10.1038/s41380-022-01524-8. Epub 2022 Apr 1. Mol Psychiatry. 2022. PMID: 35365806 Free PMC article.
We found significant positive effects for several outcomes without significant heterogeneity including TMS for symptoms of generalized anxiety disorder (SMD = -1.8 (95% CI: -2.6 to -1), and tDCS for symptoms of substance use disorder (-0.73, -1.00 to -0.46). There w …
We found significant positive effects for several outcomes without significant heterogeneity including TMS for symptoms of generalized anxie …
Severity Assessment in CDKL5 Deficiency Disorder.
Demarest S, Pestana-Knight EM, Olson HE, Downs J, Marsh ED, Kaufmann WE, Partridge CA, Leonard H, Gwadry-Sridhar F, Frame KE, Cross JH, Chin RFM, Parikh S, Panzer A, Weisenberg J, Utley K, Jaksha A, Amin S, Khwaja O, Devinsky O, Neul JL, Percy AK, Benke TA. Demarest S, et al. Pediatr Neurol. 2019 Aug;97:38-42. doi: 10.1016/j.pediatrneurol.2019.03.017. Epub 2019 Mar 27. Pediatr Neurol. 2019. PMID: 31147226 Free PMC article. Review.
A specific severity assessment is lacking, required to monitor the clinical course and needed to define the natural history and for clinical trial readiness. ...Refinement through ongoing validation is required for future clinical trials. The consensus …
A specific severity assessment is lacking, required to monitor the clinical course and needed to define the natural history and for …
Clinical Effectiveness of Muscarinic Receptor-Targeted Interventions in Neuropsychiatric Disorders: A Systematic Review.
Vaidya S, Guerin AA, Walker LC, Lawrence AJ. Vaidya S, et al. CNS Drugs. 2022 Nov;36(11):1171-1206. doi: 10.1007/s40263-022-00964-8. Epub 2022 Oct 21. CNS Drugs. 2022. PMID: 36269510 Free PMC article.
Randomised, double-blind, placebo-controlled studies were included if they investigated the effect of muscarinic receptor-targeted intervention in adults with a diagnosis of a neuropsychiatric disorder and were published in English. ...CONCLUSION: While the results …
Randomised, double-blind, placebo-controlled studies were included if they investigated the effect of muscarinic receptor-targeted in …
Site-agnostic biomarker-guided oncology drug development.
Jørgensen JT. Jørgensen JT. Expert Rev Mol Diagn. 2020 Jun;20(6):583-592. doi: 10.1080/14737159.2020.1702521. Epub 2019 Dec 12. Expert Rev Mol Diagn. 2020. PMID: 31813299
EXPERT OPINION: The recent approval of entrectinib, larotrectinib, and pembrolizumab must be regarded as a paradigm shift in biomarker-guided oncology drug development. For a site-agnostic indication, it is important to have in mind the central role of the companion diagno …
EXPERT OPINION: The recent approval of entrectinib, larotrectinib, and pembrolizumab must be regarded as a paradigm shift in biomarker-guide …
Central Endoscopy Reading in Inflammatory Bowel Diseases.
Panés J, Feagan BG, Hussain F, Levesque BG, Travis SP. Panés J, et al. J Crohns Colitis. 2016 Sep;10 Suppl 2:S542-7. doi: 10.1093/ecco-jcc/jjv171. J Crohns Colitis. 2016. PMID: 27604978 Review.
Endoscopic assessment of the presence and severity of endoscopic lesions has become an essential part of clinical trials in ulcerative colitis and Crohn's disease, for both patient eligibility and outcome measures. ...This variability can be reduced, although not co …
Endoscopic assessment of the presence and severity of endoscopic lesions has become an essential part of clinical trials in ulcerativ …
Phage therapy: delivering on the promise.
Harper DR, Anderson J, Enright MC. Harper DR, et al. Ther Deliv. 2011 Jul;2(7):935-47. doi: 10.4155/tde.11.64. Ther Deliv. 2011. PMID: 22833904 Review.
To develop phage therapy for these areas requires work carried out in accordance with the requirements of these agencies, and, driven by the current crisis of antibiotic resistance, such clinical trials are now under way. The first Phase I clinical trial of s …
To develop phage therapy for these areas requires work carried out in accordance with the requirements of these agencies, and, driven by the …
Tissue-Agnostic Drug Development.
Flaherty KT, Le DT, Lemery S. Flaherty KT, et al. Am Soc Clin Oncol Educ Book. 2017;37:222-230. doi: 10.1200/EDBK_173855. Am Soc Clin Oncol Educ Book. 2017. PMID: 28561648 Free article.
As described in U.S. regulations [21 CFR 201, CFR 201.57(c)(2)], the indications and usage section of drug labeling "must state that a drug is indicated for the treatment, prevention, mitigation, cure, or diagnosis of a recognized disease or condition or of a manifestation …
As described in U.S. regulations [21 CFR 201, CFR 201.57(c)(2)], the indications and usage section of drug labeling "must state that a drug …
Acupuncture for glaucoma.
Law SK, Li T. Law SK, et al. Cochrane Database Syst Rev. 2013 May 31;5(5):CD006030. doi: 10.1002/14651858.CD006030.pub3. Cochrane Database Syst Rev. 2013. PMID: 23728656 Free PMC article. Updated. Review.
We resolved discrepancies by discussion. MAIN RESULTS: We included one completed and one ongoing trial, and recorded seven trials awaiting assessment for eligibility. ...No statistically significant difference in visual acuity was noted at any follow-up time points. The on …
We resolved discrepancies by discussion. MAIN RESULTS: We included one completed and one ongoing trial, and recorded seven trials awa …
Evaluating the Completeness of ClinicalTrials.gov.
Stergiopoulos S, Getz KA, Blazynski C. Stergiopoulos S, et al. Ther Innov Regul Sci. 2019 May;53(3):307-317. doi: 10.1177/2168479018782885. Epub 2018 Jul 26. Ther Innov Regul Sci. 2019. PMID: 30048602
BACKGROUND: To date, although studies have been conducted to assess compliance with listing clinical trial information, to our knowledge there is nothing in the literature examining the completion and accuracy of clinical trial site information …
BACKGROUND: To date, although studies have been conducted to assess compliance with listing clinical trial information, to our …
40,387 results
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