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Page 1
Allergen immunotherapy and asthma.
Tosca MA, Olcese R, Licari A, Ciprandi G. Tosca MA, et al. Pediatr Allergy Immunol. 2020 Feb;31 Suppl 24:46-48. doi: 10.1111/pai.13161. Pediatr Allergy Immunol. 2020. PMID: 32017211
Notably, the current asthma guidelines are now recommending sublingual immunotherapy as an add-on therapy for asthma in adults and adolescents with house dust mite allergy. Clinical indications of AIT, with particular reference to pediatric asthma, mechanisms …
Notably, the current asthma guidelines are now recommending sublingual immunotherapy as an add-on therapy for asthma in adults and adolescen …
Does allergen immunotherapy for allergic rhinitis prevent asthma?
Arshad SH. Arshad SH. Ann Allergy Asthma Immunol. 2022 Sep;129(3):286-291. doi: 10.1016/j.anai.2022.04.028. Epub 2022 Apr 29. Ann Allergy Asthma Immunol. 2022. PMID: 35500864 Review.
A bystander or allergen-nonspecific effect of AIT has also been proposed-that AIT to 1 allergen might reduce the risk of development of sensitization to other allergens. Furthermore, several observational studies and clinical trials, in seasonal (pollen) and perennial (hou …
A bystander or allergen-nonspecific effect of AIT has also been proposed-that AIT to 1 allergen might reduce the risk of development of sens …
Aeroallergen sensitization and allergic disease phenotypes in Asia.
Tham EH, Lee AJ, Bever HV. Tham EH, et al. Asian Pac J Allergy Immunol. 2016 Sep;34(3):181-189. doi: 10.12932/AP0770. Asian Pac J Allergy Immunol. 2016. PMID: 27543739 Free article. Review.
Geographical and seasonal variations in aeroallergen sensitization are seen even within Asian countries and changes in aeroallergen sensitization patterns have been observed over time. Some possible reasons include climate change as well as rapid urbanization and improved …
Geographical and seasonal variations in aeroallergen sensitization are seen even within Asian countries and changes in aeroallergen sensitiz …
Local glucocorticoid synthesis regulates house dust mite-induced airway hypersensitivity in mice.
Merk VM, Phan TS, Wiedmann A, Hardy RS, Lavery GG, Brunner T. Merk VM, et al. Front Immunol. 2023 Oct 23;14:1252874. doi: 10.3389/fimmu.2023.1252874. eCollection 2023. Front Immunol. 2023. PMID: 37936704 Free PMC article.
RESULTS: Here we show that lung tissue from Hsd11b1-deficient mice synthesized significantly less GC ex vivo compared with wild type animals in response to immune cell stimulation. We further observed a drastically aggravated phenotype in Hsd11b1-deficient mice treated wit …
RESULTS: Here we show that lung tissue from Hsd11b1-deficient mice synthesized significantly less GC ex vivo compared with wild type animals …
Efficacy of Subcutaneous and Sublingual Immunotherapy for House Dust Mite Allergy: A Network Meta-Analysis-Based Comparison.
Kim JY, Jang MJ, Kim DY, Park SW, Han DH. Kim JY, et al. J Allergy Clin Immunol Pract. 2021 Dec;9(12):4450-4458.e6. doi: 10.1016/j.jaip.2021.08.018. Epub 2021 Aug 28. J Allergy Clin Immunol Pract. 2021. PMID: 34464748
BACKGROUND: Meta-analyses comparing the efficacy of sublingual immunotherapy (SLIT) and subcutaneous immunotherapy (SCIT) for house dust mite allergy are lacking. OBJECTIVE: To compare the efficacy of SLIT drops, SLIT tablets, and SCIT in patients with perenn …
BACKGROUND: Meta-analyses comparing the efficacy of sublingual immunotherapy (SLIT) and subcutaneous immunotherapy (SCIT) for house dust …
Real-world, long-term effectiveness of allergy immunotherapy in allergic rhinitis: Subgroup analyses of the REACT study.
Contoli M, Porsbjerg C, Buchs S, Larsen JR, Freemantle N, Fritzsching B. Contoli M, et al. J Allergy Clin Immunol. 2023 Aug;152(2):445-452.e4. doi: 10.1016/j.jaci.2023.02.024. Epub 2023 Mar 3. J Allergy Clin Immunol. 2023. PMID: 36871918 Free article.
RESULTS: Subcutaneous immunotherapy (SCIT) and SLIT tablets showed similarly greater reductions in AR prescriptions than controls (SCIT vs SLIT tablets: year 3, P = .15; year 5, P = .43). Comparably greater reductions in AR prescriptions were observed for grass- and house …
RESULTS: Subcutaneous immunotherapy (SCIT) and SLIT tablets showed similarly greater reductions in AR prescriptions than controls (SCIT vs S …
Intra-cervical lymphatic immunotherapy for dust mite-induced allergic rhinoconjunctivitis in children: a 3-year prospective randomized controlled trial.
Wang Q, Wang K, Qin Y, Huang W, Li Y, Yu Q, Xiong Y, Guo Y, Zheng R, Tang J. Wang Q, et al. Front Immunol. 2023 Aug 1;14:1144813. doi: 10.3389/fimmu.2023.1144813. eCollection 2023. Front Immunol. 2023. PMID: 37593733 Free PMC article. Clinical Trial.
METHODS: This is a prospective randomized controlled study. A total of 50 allergic rhinoconjunctivitis children with dust mite allergy was randomly divided into ICLIT group and SCIT group, receiving three cervical intralymphatic injections of dust mite allerg …
METHODS: This is a prospective randomized controlled study. A total of 50 allergic rhinoconjunctivitis children with dust mite …
Allergen desensitization reduces the severity of relapsed alopecia areata in dust-mite allergic patients.
Zeng Z, Li S, Ye Y, Ling Y, Gong Y, Zi X, Yang J, McElwee KJ, Zhang X. Zeng Z, et al. Exp Dermatol. 2023 Jul;32(7):1108-1119. doi: 10.1111/exd.14819. Epub 2023 Apr 28. Exp Dermatol. 2023. PMID: 37114716
At the end of the 3-year desensitization course, the AIT-TrAA group presented with lower SALT scores than the TrAA group, especially in non-alopecia totalis/universalis (AT/U) patients and pre-adolescent AT/U patients (age 14). ...After desensitization, elevation of IL-5 a …
At the end of the 3-year desensitization course, the AIT-TrAA group presented with lower SALT scores than the TrAA group, especially …
Functional and Immunoreactive Levels of IgG4 Correlate with Clinical Responses during the Maintenance Phase of House Dust Mite Immunotherapy.
Feng M, Su Q, Lai X, Xian M, Shi X, Wurtzen PA, Qin R, Zeng X, Li J. Feng M, et al. J Immunol. 2018 Jun 15;200(12):3897-3904. doi: 10.4049/jimmunol.1701690. Epub 2018 May 4. J Immunol. 2018. PMID: 29728509
Allergen-specific immunotherapy for house dust mite allergy is effective, but there are no validated biomarkers reflecting or predicting the clinical efficacy. ...Serum obtained from SCIT patients significantly inhibited D. pteronyssinus-sIgE binding t …
Allergen-specific immunotherapy for house dust mite allergy is effective, but there are no validated biomarkers reflect …
Immune signatures predict response to house dust mite subcutaneous immunotherapy in patients with allergic rhinitis.
Wang N, Song J, Sun SR, Zhu KZ, Li JX, Wang ZC, Guo CL, Xiang WX, Tong YL, Zeng M, Wang H, Xu XY, Yao Y, Liu Z. Wang N, et al. Allergy. 2024 May;79(5):1230-1241. doi: 10.1111/all.16068. Epub 2024 Feb 25. Allergy. 2024. PMID: 38403941
BACKGROUND: Identifying predictive biomarkers for allergen immunotherapy response is crucial for enhancing clinical efficacy. This study aims to identify such biomarkers in patients with allergic rhinitis (AR) undergoing subcutaneous immunotherapy (SCIT) for house dust …
BACKGROUND: Identifying predictive biomarkers for allergen immunotherapy response is crucial for enhancing clinical efficacy. This st …
89 results