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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1981 1
1991 1
1994 1
1997 1
1999 1
2000 3
2003 2
2005 2
2006 1
2007 2
2008 3
2009 7
2010 5
2011 5
2012 7
2013 13
2014 18
2015 14
2016 14
2017 10
2018 13
2019 11
2020 16
2021 18
2022 17
2023 10
2024 4

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170 results

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Page 1
AFP-L3 and DCP strongly predict early hepatocellular carcinoma recurrence after liver transplantation.
Norman JS, Li PJ, Kotwani P, Shui AM, Yao F, Mehta N. Norman JS, et al. J Hepatol. 2023 Dec;79(6):1469-1477. doi: 10.1016/j.jhep.2023.08.020. Epub 2023 Sep 7. J Hepatol. 2023. PMID: 37683735
BACKGROUND & AIMS: Alpha-fetoprotein (AFP) predicts hepatocellular carcinoma (HCC) recurrence after liver transplant (LT) but remains an imperfect biomarker. ...In this prospective study, the biomarkers DCP (des-gamma-carboxyprothrombin) and AFP-L3 (AFP bound to Lens c …
BACKGROUND & AIMS: Alpha-fetoprotein (AFP) predicts hepatocellular carcinoma (HCC) recurrence after liver transplant (LT) but rem …
Cell-free DNA testing for early hepatocellular carcinoma surveillance.
Chen L, Wu T, Fan R, Qian YS, Liu JF, Bai J, Zheng B, Liu XL, Zheng D, Du LT, Jiang GQ, Wang YC, Fan XT, Deng GH, Wang CY, Shen F, Hu HP, Zhang QZ, Ye YN, Zhang J, Gao YH, Xia J, Yan HD, Liang MF, Yu YL, Sun FM, Gao YJ, Sun J, Zhong CX, Wang Y, Wang H, Kong F, Chen JM, Wen H, Wu BM, Wang CX, Wu L, Hou JL, Wang HY. Chen L, et al. EBioMedicine. 2024 Feb;100:104962. doi: 10.1016/j.ebiom.2023.104962. Epub 2024 Jan 6. EBioMedicine. 2024. PMID: 38184937 Free PMC article.
Surveillance performance of PreCar Score alone or in combination with US/AFP was evaluated in Stage cohort. ...INTERPRETATION: Our study developed and validated a cfDNA-based screening tool (PreCar Score) for HCC in cohorts at high risk. The combination of PreCar …
Surveillance performance of PreCar Score alone or in combination with US/AFP was evaluated in Stage cohort. ...INTERPRETATION: Our st …
Liquid biopsy in the clinical management of hepatocellular carcinoma.
von Felden J, Garcia-Lezana T, Schulze K, Losic B, Villanueva A. von Felden J, et al. Gut. 2020 Nov;69(11):2025-2034. doi: 10.1136/gutjnl-2019-320282. Epub 2020 Sep 3. Gut. 2020. PMID: 32883873 Review.
A variety of translational liquid biopsy studies have been carried out to address clinical needs, such as early hepatocellular carcinoma detection and prediction of treatment response. To this regard, methylation profiling of circulating tumour DNA has …
A variety of translational liquid biopsy studies have been carried out to address clinical needs, such as early hepatocellular …
Personalized treatment of patients with very early hepatocellular carcinoma.
Vitale A, Peck-Radosavljevic M, Giannini EG, Vibert E, Sieghart W, Van Poucke S, Pawlik TM. Vitale A, et al. J Hepatol. 2017 Feb;66(2):412-423. doi: 10.1016/j.jhep.2016.09.012. Epub 2016 Sep 24. J Hepatol. 2017. PMID: 27677712 Review.
., presence or absence of portal hypertension, model for end-stage liver disease score, Child-Pugh score 5 or 6, bilirubin level) and tumor characteristics (i.e., location, alpha-fetoprotein values, pathological features such as microvascular invasion, tumor grade a …
., presence or absence of portal hypertension, model for end-stage liver disease score, Child-Pugh score 5 or 6, bilirubin lev …
Early Prediction of Response of Hepatocellular Carcinoma to Yttrium-90 Radiation Segmentectomy Using a Machine Learning MR Imaging Radiomic Approach.
Marinelli B, Chen M, Stocker D, Charles D, Radell J, Lee JY, Fauveau V, Bello-Martinez R, Kim E, Taouli B. Marinelli B, et al. J Vasc Interv Radiol. 2023 Oct;34(10):1794-1801.e2. doi: 10.1016/j.jvir.2023.06.023. Epub 2023 Jun 24. J Vasc Interv Radiol. 2023. PMID: 37364730
PURPOSE: To assess the accuracy of a machine learning (ML) approach based on magnetic resonance (MR) imaging radiomic quantification obtained before treatment and early after treatment for prediction of early hepatocellular carcinoma (HCC) response to …
PURPOSE: To assess the accuracy of a machine learning (ML) approach based on magnetic resonance (MR) imaging radiomic quantification obtaine …
AFP-L3 for the diagnosis of early hepatocellular carcinoma: A meta-analysis.
Zhou JM, Wang T, Zhang KH. Zhou JM, et al. Medicine (Baltimore). 2021 Oct 29;100(43):e27673. doi: 10.1097/MD.0000000000027673. Medicine (Baltimore). 2021. PMID: 34713864 Free PMC article.
BACKGROUND: The present study aimed to systematically evaluate the diagnostic value of an isoform of alpha-fetoprotein (AFP), AFP-L3, for early hepatocellular carcinoma (HCC) by a meta-analysis. METHODS: Diagnostic reports of AFP-L3% in early HCC were searche …
BACKGROUND: The present study aimed to systematically evaluate the diagnostic value of an isoform of alpha-fetoprotein (AFP), AFP-L3, for …
Preoperative serum ctDNA predicts early hepatocellular carcinoma recurrence and response to systemic therapies.
Fu Y, Yang Z, Hu Z, Yang Z, Pan Y, Chen J, Wang J, Hu D, Zhou Z, Xu L, Chen M, Zhang Y. Fu Y, et al. Hepatol Int. 2022 Aug;16(4):868-878. doi: 10.1007/s12072-022-10348-1. Epub 2022 Jun 8. Hepatol Int. 2022. PMID: 35674872
CONCLUSION: Preoperative serum ctDNA can be a practical noninvasive approach to predict recurrence after surgery and response to systemic therapies. ctDNA-guided HCC management should be recommended....
CONCLUSION: Preoperative serum ctDNA can be a practical noninvasive approach to predict recurrence after surgery and response to syst …
Development of pre and post-operative models to predict early recurrence of hepatocellular carcinoma after surgical resection.
Chan AWH, Zhong J, Berhane S, Toyoda H, Cucchetti A, Shi K, Tada T, Chong CCN, Xiang BD, Li LQ, Lai PBS, Mazzaferro V, García-Fiñana M, Kudo M, Kumada T, Roayaie S, Johnson PJ. Chan AWH, et al. J Hepatol. 2018 Dec;69(6):1284-1293. doi: 10.1016/j.jhep.2018.08.027. Epub 2018 Sep 18. J Hepatol. 2018. PMID: 30236834 Free article.
BACKGROUND & AIMS: Resection is the most widely used potentially curative treatment for patients with early hepatocellular carcinoma (HCC). However, recurrence within 2 years occurs in 30-50% of patients, being the major cause of mortality. ...Median surv …
BACKGROUND & AIMS: Resection is the most widely used potentially curative treatment for patients with early hepatocellular …
Construction and validation of a predictive model for hepatocellular carcinoma based on serum markers.
Zheng L, Huang Z, Li X, He M, Liu X, Zheng G, Zhou X, Liu L. Zheng L, et al. BMC Gastroenterol. 2022 Sep 13;22(1):418. doi: 10.1186/s12876-022-02489-2. BMC Gastroenterol. 2022. PMID: 36100887 Free PMC article.
BACKGROUND: Early hepatocellular carcinoma (HCC) detection with non-invasive biomarkers remains an unmet clinical need. ...RESULTS: Five independent predictive variables for HCC onset and two general characteristics of patients (age and gender) were in …
BACKGROUND: Early hepatocellular carcinoma (HCC) detection with non-invasive biomarkers remains an unmet clinical need. …
Resectable and transplantable hepatocellular carcinoma: Integration of liver stiffness assessment in the decision-making algorithm.
Tortajada P, Doamba R, Cano L, Ghallab M, Allard MA, Ciacio O, Pittau G, Salloum C, Cherqui D, Adam R, Sa Cunha A, Azoulay D, Pascale A, Vibert E, Golse N. Tortajada P, et al. Surgery. 2022 Dec;172(6):1704-1711. doi: 10.1016/j.surg.2022.08.012. Epub 2022 Oct 12. Surgery. 2022. PMID: 36241470
We developed a predictive score for recurrence over time using Cox univariate regression and multivariate analysis with a combination plot before selecting the optimal thresholds (receiver operating characteristic curves + Youden test). ...Patients experiencing earl …
We developed a predictive score for recurrence over time using Cox univariate regression and multivariate analysis with a comb …
170 results