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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1976 2
1977 1
1978 1
1979 1
1980 2
1981 1
1982 1
1983 1
1986 2
1989 4
1991 3
1992 5
1993 3
1994 3
1995 3
1996 1
1997 4
1998 1
1999 1
2000 6
2002 2
2003 2
2004 2
2005 2
2006 6
2007 4
2008 6
2009 3
2010 8
2011 9
2012 6
2013 5
2014 4
2015 3
2016 4
2017 1
2018 6
2019 5
2020 2
2021 3
2022 2
2023 2
2024 0

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123 results

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Page 1
Brincidofovir: A Novel Agent for the Treatment of Smallpox.
Huston J, Curtis S, Egelund EF. Huston J, et al. Ann Pharmacother. 2023 Oct;57(10):1198-1206. doi: 10.1177/10600280231151751. Epub 2023 Jan 23. Ann Pharmacother. 2023. PMID: 36688308 Review.
DATA SYNTHESIS: Two surrogate animal models were included in the Food and Drug Administration's (FDA) decision to approve brincidofovir: ectromelia virus in mice and rabbitpox in rabbits. Phases 2 and 3 studies established safety for approval. ...In healthy volunteers and …
DATA SYNTHESIS: Two surrogate animal models were included in the Food and Drug Administration's (FDA) decision to approve brincidofovir: …
Reassessment of Evidence about Coinfection of Chickenpox and Monkeypox (Mpox) in African Children.
Khallafallah O, Grose C. Khallafallah O, et al. Viruses. 2022 Dec 15;14(12):2800. doi: 10.3390/v14122800. Viruses. 2022. PMID: 36560805 Free PMC article. Review.
In two large epidemiology studies of monkeypox outbreaks, the investigators observed a sizable number of coinfections of chickenpox (varicella) and monkeypox. ...Based on the above observations, we conclude that, when chickenpox precedes monkeypox, priming of the im …
In two large epidemiology studies of monkeypox outbreaks, the investigators observed a sizable number of coinfections of chickenpox ( …
Sirenomelia: A Multi-systemic Polytopic Field Defect with Ongoing Controversies.
Boer LL, Morava E, Klein WM, Schepens-Franke AN, Oostra RJ. Boer LL, et al. Birth Defects Res. 2017 Jun 1;109(10):791-804. doi: 10.1002/bdr2.1049. Epub 2017 May 16. Birth Defects Res. 2017. PMID: 28509418 Review.
To expand on the latter, we included the external and internal dysmorphology of one third trimester sirenomelic fetus from our anatomical museum collection, in which multiple concomitant but discordant anomalies were observed compared with classic sirenomelia, and was diag …
To expand on the latter, we included the external and internal dysmorphology of one third trimester sirenomelic fetus from our anatomical mu …
Sirenomelia: A Case Report.
Kattel P. Kattel P. JNMA J Nepal Med Assoc. 2018 Nov-Dec;56(214):974-976. doi: 10.31729/jnma.3884. JNMA J Nepal Med Assoc. 2018. PMID: 31065147 Free PMC article.
After confirming the diagnosis, preterm vaginal delivery was performed with a live baby of 1250 gm consisting of multiple congenital anomalies and poor Apgar score. Such cases do occur at our set-up so that if anomaly scanning is done routinely, they could be picked up ear …
After confirming the diagnosis, preterm vaginal delivery was performed with a live baby of 1250 gm consisting of multiple congenital anomali …
Patterns in multimalformed babies and the question of the relationship between sirenomelia and VACTERL.
Schüler L, Salzano FM. Schüler L, et al. Am J Med Genet. 1994 Jan 1;49(1):29-35. doi: 10.1002/ajmg.1320490108. Am J Med Genet. 1994. PMID: 8172248 Review.
The frequencies of these defects were intermediate between those observed for VACTERL or sirenomelia, supporting the idea that these conditions have a similar pathogenesis. Statistical approaches like this one may be helpful in identifying processes and biological entities …
The frequencies of these defects were intermediate between those observed for VACTERL or sirenomelia, supporting the idea that these …
Virulent Poxviruses Inhibit DNA Sensing by Preventing STING Activation.
Georgana I, Sumner RP, Towers GJ, Maluquer de Motes C. Georgana I, et al. J Virol. 2018 Apr 27;92(10):e02145-17. doi: 10.1128/JVI.02145-17. Print 2018 May 15. J Virol. 2018. PMID: 29491158 Free PMC article.
Similar inhibition of DNA-induced STING activation was also observed for cowpox and ectromelia viruses. Our data demonstrate that virulent poxviruses possess mechanisms for targeting DNA sensing at the level of the cGAS-STING axis and that these mechanisms do not op …
Similar inhibition of DNA-induced STING activation was also observed for cowpox and ectromelia viruses. Our data demonstrate t …
Cytokines and immunity to viral infections.
Ramshaw IA, Ramsay AJ, Karupiah G, Rolph MS, Mahalingam S, Ruby JC. Ramshaw IA, et al. Immunol Rev. 1997 Oct;159:119-35. doi: 10.1111/j.1600-065x.1997.tb01011.x. Immunol Rev. 1997. PMID: 9416507 Review.
Surprisingly, not only the TNFR1, but also the TNFR2, was able to mediate the antiviral effects of TNF-alpha in vivo, whilst the antiviral activity observed following CD40-CD40L interaction is a newly defined function which may involve apoptosis of infected cells. Through …
Surprisingly, not only the TNFR1, but also the TNFR2, was able to mediate the antiviral effects of TNF-alpha in vivo, whilst the antiviral a …
Sirenomelia in twin pregnancy: A case report and literature review.
Xu T, Wang X, Luo H, Yu H. Xu T, et al. Medicine (Baltimore). 2018 Dec;97(51):e13672. doi: 10.1097/MD.0000000000013672. Medicine (Baltimore). 2018. PMID: 30572488 Free PMC article. Review.
OUTCOMES: At 34+2 gestational weeks, the demise of the malformed twin occurred, while fetal heart rate monitoring of the normal twin was abnormal, and an emergency cesarean section was performed. A healthy male baby was delivered with Apgar scores of 10 and 10 at 1 and 5 m …
OUTCOMES: At 34+2 gestational weeks, the demise of the malformed twin occurred, while fetal heart rate monitoring of the normal twin was abn …
Limb-body wall defect. Is there a defensible hypothesis and can it explain all the associated anomalies?
Hunter AG, Seaver LH, Stevenson RE. Hunter AG, et al. Am J Med Genet A. 2011 Sep;155A(9):2045-59. doi: 10.1002/ajmg.a.34161. Epub 2011 Aug 3. Am J Med Genet A. 2011. PMID: 21815262 Review.
We conclude that this association of malformations originates as early as the embryonic disc stage, and that some of the observed associated anomalies are secondary complications of the primary disturbance in embryogenesis. We propose a new explanation for the atypical fac …
We conclude that this association of malformations originates as early as the embryonic disc stage, and that some of the observed ass …
Physical performance of children with longitudinal fibular deficiency (fibular hemimelia).
Morris EJ, Tofts L, Patterson M, Birke O, Adams R, Epps A, Knox K, McKay MJ, Baldwin JN, Burns J, Pacey V. Morris EJ, et al. Disabil Rehabil. 2022 Jun;44(12):2763-2773. doi: 10.1080/09638288.2020.1849420. Epub 2020 Dec 17. Disabil Rehabil. 2022. PMID: 33331793

Children with LFD performed at a lower level than their unaffected peers, on all measures of physical performance (mean 2.1 z-scores lower, all p < 0.01), except in long jump (p = 0.27). When comparing the performance of children with LFD to their unaffected peers acros

…
Children with LFD performed at a lower level than their unaffected peers, on all measures of physical performance (mean 2.1 z-scores …
123 results