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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1998 3
1999 16
2000 7
2001 19
2002 22
2003 26
2004 25
2005 21
2006 27
2007 26
2008 31
2009 27
2010 25
2011 24
2012 41
2013 34
2014 41
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228 results

Results by year

Filters applied: Meta-Analysis, Review, Systematic Review, in the last 10 years. Clear all
Page 1
Efavirenz.
[No authors listed] [No authors listed] 2024 Feb 15. Drugs and Lactation Database (LactMed®) [Internet]. Bethesda (MD): National Institute of Child Health and Human Development; 2006–. 2024 Feb 15. Drugs and Lactation Database (LactMed®) [Internet]. Bethesda (MD): National Institute of Child Health and Human Development; 2006–. PMID: 30000594 Free Books & Documents. Review.
Efavirenz is excreted into breastmilk and small amounts are found in the serum of some infants. Treatment of mothers of HIV-positive mothers with efavirenz does not appear to affect growth and development of their HIV-negative breastfed infants. ...
Efavirenz is excreted into breastmilk and small amounts are found in the serum of some infants. Treatment of mothers of HIV-positive …
Efavirenz: History, Development and Future.
Costa B, Vale N. Costa B, et al. Biomolecules. 2022 Dec 31;13(1):88. doi: 10.3390/biom13010088. Biomolecules. 2022. PMID: 36671473 Free PMC article. Review.
In 1998, the FDA authorized efavirenz for the treatment of HIV-1 infection. Patients formerly required three 200 mg efavirenz capsules daily, which was rapidly updated to a 600 mg tablet that only required one tablet per day. ...Efavirenz has been a primary f …
In 1998, the FDA authorized efavirenz for the treatment of HIV-1 infection. Patients formerly required three 200 mg efavirenz …
Efavirenz as a psychotropic drug.
Zareifopoulos N, Lagadinou M, Karela A, Pouliasi F, Economou I, Tsigkou A, Velissaris D. Zareifopoulos N, et al. Eur Rev Med Pharmacol Sci. 2020 Oct;24(20):10729-10735. doi: 10.26355/eurrev_202010_23433. Eur Rev Med Pharmacol Sci. 2020. PMID: 33155233 Free article. Review.
The purpose of this article is to review the psychotropic properties of efavirenz, which are the most important adverse events associated with the drug and commonly result in treatment discontinuation. ...Efavirenz interacts with many of the same molecular targets a …
The purpose of this article is to review the psychotropic properties of efavirenz, which are the most important adverse events associ …
Efavirenz Metabolism: Influence of Polymorphic CYP2B6 Variants and Stereochemistry.
Wang PF, Neiner A, Kharasch ED. Wang PF, et al. Drug Metab Dispos. 2019 Oct;47(10):1195-1205. doi: 10.1124/dmd.119.086348. Epub 2019 Jul 19. Drug Metab Dispos. 2019. PMID: 31324697 Free PMC article. Review.
Metabolism of R-efavirenz by CYP2B6 remains unexplored. This investigation assessed S-efavirenz metabolism by clinically relevant CYP2B6 genetic variants. ...Rates of R-efavirenz metabolism were approximately 1/10 those of S-efavirenz for wild-type CYP …
Metabolism of R-efavirenz by CYP2B6 remains unexplored. This investigation assessed S-efavirenz metabolism by clinically relev …
Efavirenz.
[No authors listed] [No authors listed] 2018 Feb 10. LiverTox: Clinical and Research Information on Drug-Induced Liver Injury [Internet]. Bethesda (MD): National Institute of Diabetes and Digestive and Kidney Diseases; 2012–. 2018 Feb 10. LiverTox: Clinical and Research Information on Drug-Induced Liver Injury [Internet]. Bethesda (MD): National Institute of Diabetes and Digestive and Kidney Diseases; 2012–. PMID: 31643839 Free Books & Documents. Review.
Efavirenz is a nonnucleoside reverse transcriptase inhibitor used in combination with other agents in the therapy of human immunodeficiency virus (HIV) infection. Efavirenz is associated with a low rate of serum enzyme elevations during therapy and is an uncommon, b …
Efavirenz is a nonnucleoside reverse transcriptase inhibitor used in combination with other agents in the therapy of human immunodefi …
Efavirenz and the CNS: what we already know and questions that need to be answered.
Apostolova N, Funes HA, Blas-Garcia A, Galindo MJ, Alvarez A, Esplugues JV. Apostolova N, et al. J Antimicrob Chemother. 2015 Oct;70(10):2693-708. doi: 10.1093/jac/dkv183. Epub 2015 Jul 22. J Antimicrob Chemother. 2015. PMID: 26203180 Review.
However, growing concern about its adverse effects has sometimes led to efavirenz being replaced by other drugs in the initial treatment selection or to switching of therapy to efavirenz-free regimens in experienced patients. ...The mechanisms responsible for efa …
However, growing concern about its adverse effects has sometimes led to efavirenz being replaced by other drugs in the initial treatm …
A Concise Analytical Profile of Efavirenz: Analytical Methodologies.
Ambhore JP, Chaudhari SR, Cheke RS, Kharkar PS. Ambhore JP, et al. Crit Rev Anal Chem. 2022;52(7):1583-1592. doi: 10.1080/10408347.2021.1895711. Epub 2021 Mar 15. Crit Rev Anal Chem. 2022. PMID: 33722117 Review.
Therefore, the proposed review integrally addresses the analytical reports of efavirenz recorded in the literature databases like Scopus, Web of Science, Google Scholar, Pub-Med, and through many other sources. It has been remarked that for the development of efavirenz …
Therefore, the proposed review integrally addresses the analytical reports of efavirenz recorded in the literature databases like Sco …
Efavirenz: What is known about the cellular mechanisms responsible for its adverse effects.
Apostolova N, Blas-Garcia A, Galindo MJ, Esplugues JV. Apostolova N, et al. Eur J Pharmacol. 2017 Oct 5;812:163-173. doi: 10.1016/j.ejphar.2017.07.016. Epub 2017 Jul 8. Eur J Pharmacol. 2017. PMID: 28690189 Review.
However, due to the efficacy of combined antiretroviral therapy (cART), it has ceased to be a mortal condition, becoming a chronic disease instead. Efavirenz, the most prescribed non-nucleoside analogue reverse transcriptase inhibitor (NNRTI), has been a key component of c …
However, due to the efficacy of combined antiretroviral therapy (cART), it has ceased to be a mortal condition, becoming a chronic disease i …
PharmGKB summary: Efavirenz pathway, pharmacokinetics.
McDonagh EM, Lau JL, Alvarellos ML, Altman RB, Klein TE. McDonagh EM, et al. Pharmacogenet Genomics. 2015 Jul;25(7):363-76. doi: 10.1097/FPC.0000000000000145. Pharmacogenet Genomics. 2015. PMID: 25966836 Free PMC article. Review. No abstract available.
Efavirenz-Based Regimens in Antiretroviral-Naive HIV-Infected Patients: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.
Kryst J, Kawalec P, Pilc A. Kryst J, et al. PLoS One. 2015 May 1;10(5):e0124279. doi: 10.1371/journal.pone.0124279. eCollection 2015. PLoS One. 2015. PMID: 25933004 Free PMC article. Review.
Efavirenz, a non-nucleoside reverse-transcriptase inhibitor (NNRTI) is one of the most commonly prescribed antiretroviral drugs. ...Beneficial safety profile of InSTI-based and CCR5-based therapy over efavirenz-based treatment needs further studies....
Efavirenz, a non-nucleoside reverse-transcriptase inhibitor (NNRTI) is one of the most commonly prescribed antiretroviral drugs. ...B …
228 results