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Quoted phrase not found in phrase index: "Elevated circulating branched chain amino acid concentration"
Page 1
Serum branched chain amino acids: an effective indicator of diabetic kidney disease.
Liu M, Yang Y, Liu Y, Peng X, Hou Y, Zhang X, Sun H, Shan C. Liu M, et al. Front Endocrinol (Lausanne). 2023 Nov 27;14:1269633. doi: 10.3389/fendo.2023.1269633. eCollection 2023. Front Endocrinol (Lausanne). 2023. PMID: 38089615 Free PMC article.
INTRODUCTION: In recent years, there has been a growing association between elevated circulating levels of branched-chain amino acids (BCAA) and diabetes mellitus. ...These observations point to the possibility that serum BCAA concentrati …
INTRODUCTION: In recent years, there has been a growing association between elevated circulating levels of branched- …
Circulating Metabolites and Cardiovascular Disease in Asians with Chronic Kidney Disease.
Cai J, Chong CCY, Cheng CY, Lim CC, Sabanayagam C. Cai J, et al. Cardiorenal Med. 2023;13(1):301-309. doi: 10.1159/000533741. Epub 2023 Sep 5. Cardiorenal Med. 2023. PMID: 37669626 Free PMC article.
INTRODUCTION: Chronic kidney disease (CKD) is a growing public health problem, with significant burden of cardiovascular disease and mortality. The risk of cardiovascular disease in CKD is elevated beyond that predicted by traditional cardiovascular risk factors, su …
INTRODUCTION: Chronic kidney disease (CKD) is a growing public health problem, with significant burden of cardiovascular disease and mortali …
Longitudinal Branched-Chain Amino Acids, Lifestyle Intervention, and Type 2 Diabetes in the Finnish Diabetes Prevention Study.
Kivelä J, Meinilä J, Uusitupa M, Tuomilehto J, Lindström J. Kivelä J, et al. J Clin Endocrinol Metab. 2022 Sep 28;107(10):2844-2853. doi: 10.1210/clinem/dgac463. J Clin Endocrinol Metab. 2022. PMID: 35917829 Free PMC article.
CONTEXT: Circulating branched-chain amino acids (BCAAs) are associated with the risk of type 2 diabetes (T2D). ...RESULTS: Elevated baseline BCAAs predicted the incidence of T2D in the control group (hazard ratio [HR] 1.05 per 10 m …
CONTEXT: Circulating branched-chain amino acids (BCAAs) are associated with the risk of type 2 diabetes ( …
Branched-chain Amino Acids and Relationship With Inflammation in Youth With Obesity: A Randomized Controlled Intervention Study.
Cosentino RG, Churilla JR, Josephson S, Molle-Rios Z, Hossain MJ, Prado WL, Balagopal PB. Cosentino RG, et al. J Clin Endocrinol Metab. 2021 Oct 21;106(11):3129-3139. doi: 10.1210/clinem/dgab538. J Clin Endocrinol Metab. 2021. PMID: 34286837 Clinical Trial.
CONTEXT: Elevated concentrations of branched-chain amino acids (BCAA) are strong predictors of type 2 diabetes mellitus (T2DM). ...Independent t tests, analysis of covariance, and mixed-effect models were used for analysis of the data. RE …
CONTEXT: Elevated concentrations of branched-chain amino acids (BCAA) are strong predictors of typ …
Divergent Survival Outcomes Associated with Elevated Branched-Chain Amino Acid Levels among Older Adults with or without Hypertension and Diabetes: A Validated, Prospective, Longitudinal Follow-Up Study.
Fung E, Ng KH, Kwok T, Lui LT, Palaniswamy S, Chan Q, Lim LL, Wiklund P, Xie S, Turner C, Elshorbagy AK, Refsum H, Leung JCS, Kong APS, Chan JCN, Järvelin MR, Woo J. Fung E, et al. Biomolecules. 2023 Aug 16;13(8):1252. doi: 10.3390/biom13081252. Biomolecules. 2023. PMID: 37627317 Free PMC article.
Branched-chain amino acids are critical metabolic intermediates that can indicate increased risk of cardiometabolic disease when levels are elevated or, alternatively, suggest sufficient mitochondrial energy metabolism and reserve in old age. .. …
Branched-chain amino acids are critical metabolic intermediates that can indicate increased risk of cardiometabo …
High concentration of branched-chain amino acids promotes oxidative stress, inflammation and migration of human peripheral blood mononuclear cells via mTORC1 activation.
Zhenyukh O, Civantos E, Ruiz-Ortega M, Sánchez MS, Vázquez C, Peiró C, Egido J, Mas S. Zhenyukh O, et al. Free Radic Biol Med. 2017 Mar;104:165-177. doi: 10.1016/j.freeradbiomed.2017.01.009. Epub 2017 Jan 13. Free Radic Biol Med. 2017. PMID: 28089725 Free article.
Leucine, isoleucine and valine are essential aminoacids termed branched-chain amino acids (BCAA) due to its aliphatic side-chain. ...These data suggest that high concentrations of BCAA could exert deleterious effects on circulating blo …
Leucine, isoleucine and valine are essential aminoacids termed branched-chain amino acids (BCAA) due to its alip …
Circulating branched-chain amino acid concentrations are associated with obesity and future insulin resistance in children and adolescents.
McCormack SE, Shaham O, McCarthy MA, Deik AA, Wang TJ, Gerszten RE, Clish CB, Mootha VK, Grinspoon SK, Fleischman A. McCormack SE, et al. Pediatr Obes. 2013 Feb;8(1):52-61. doi: 10.1111/j.2047-6310.2012.00087.x. Epub 2012 Sep 7. Pediatr Obes. 2013. PMID: 22961720 Free PMC article.
What is already known about this subject Circulating concentrations of branched-chain amino acids (BCAAs) can affect carbohydrate metabolism in skeletal muscle, and therefore may alter insulin sensitivity. ...BACKGROUND: Branched-chain …
What is already known about this subject Circulating concentrations of branched-chain amino acids (BCAAs) …
The Effect of One Anastomosis Gastric Bypass on Branched-Chain Fatty Acid and Branched-Chain Amino Acid Metabolism in Subjects with Morbid Obesity.
Pakiet A, Wilczynski M, Rostkowska O, Korczynska J, Jabłonska P, Kaska L, Proczko-Stepaniak M, Sobczak E, Stepnowski P, Magkos F, Sledzinski T, Mika A. Pakiet A, et al. Obes Surg. 2020 Jan;30(1):304-312. doi: 10.1007/s11695-019-04157-z. Obes Surg. 2020. PMID: 31440954 Clinical Trial.
BACKGROUND: Subjects with morbid obesity have low levels of serum branched-chain fatty acids (BCFAs), which correlate inversely with insulin resistance, hypertriglyceridemia, and inflammation. Recent evidence suggests BCFAs are produced during branched …
BACKGROUND: Subjects with morbid obesity have low levels of serum branched-chain fatty acids (BCFAs), which correlate i …
Effect of insulin sensitizer therapy on amino acids and their metabolites.
Irving BA, Carter RE, Soop M, Weymiller A, Syed H, Karakelides H, Bhagra S, Short KR, Tatpati L, Barazzoni R, Nair KS. Irving BA, et al. Metabolism. 2015 Jun;64(6):720-8. doi: 10.1016/j.metabol.2015.01.008. Epub 2015 Jan 22. Metabolism. 2015. PMID: 25733201 Free PMC article. Clinical Trial.
AIMS: Prior studies have reported that elevated concentrations of several plasma amino acids (AA), particularly branched chain (BCAA) and aromatic AA predict the onset of type 2 diabetes. We sought to test the hypothesis that circulati …
AIMS: Prior studies have reported that elevated concentrations of several plasma amino acids (AA), particularly bran …
Hepatic encephalopathy as a complication of liver cirrhosis: an Asian perspective.
Moriwaki H, Shiraki M, Iwasa J, Terakura Y. Moriwaki H, et al. J Gastroenterol Hepatol. 2010 May;25(5):858-63. doi: 10.1111/j.1440-1746.2010.06242.x. J Gastroenterol Hepatol. 2010. PMID: 20546438 Review.
Accepted concepts regarding the pathophysiology of hepatic encephalopathy are that the endogenous neurotoxic substances, including ammonia: (i) escape from catabolism by the liver due both to the impaired function of the cirrhotic liver and also to the presence of portal systemic …
Accepted concepts regarding the pathophysiology of hepatic encephalopathy are that the endogenous neurotoxic substances, including ammonia: …
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