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Quoted phrase not found in phrase index: "Elevated urinary creatine level"
Page 1
Laboratory and metabolic investigations.
Morava E, Oglesbee D. Morava E, et al. Handb Clin Neurol. 2023;194:167-172. doi: 10.1016/B978-0-12-821751-1.00012-9. Handb Clin Neurol. 2023. PMID: 36813311 Review.
According to the guidelines, the work-up should include the assessment of complete blood count, creatine phosphokinase, transaminases, albumin, postprandial lactate and pyruvate (lactate/pyruvate ratio when the lactate level is elevated), uric acid, thymidine …
According to the guidelines, the work-up should include the assessment of complete blood count, creatine phosphokinase, transaminases …
Urinary titin as a biomarker in Fukuyama congenital muscular dystrophy.
Sato T, Awano H, Ishiguro K, Shichiji M, Murakami T, Shirakawa T, Matsuo M, Nagata S, Ishigaki K. Sato T, et al. Neuromuscul Disord. 2021 Mar;31(3):194-197. doi: 10.1016/j.nmd.2021.01.005. Epub 2021 Jan 13. Neuromuscul Disord. 2021. PMID: 33563515
Recently, an ELISA assay to quantify the N-terminal fragment of titin in urine was developed. Urinary titin concentration is elevated in patients with Duchenne muscular dystrophy (DMD) compared to normal controls. ...Especially in homozygotes, the score for gross mo …
Recently, an ELISA assay to quantify the N-terminal fragment of titin in urine was developed. Urinary titin concentration is eleva …
Biomarkers, Creatine Kinase, and Kidney Function of Special Operation Candidates During Intense Physiological Training.
Shumway J, Irvin A, Shia R, Goodyear CD. Shumway J, et al. Mil Med. 2020 Aug 14;185(7-8):e982-e987. doi: 10.1093/milmed/usaa079. Mil Med. 2020. PMID: 32601703
Unfortunately, none of the biomarkers assessed were indicative of passing training, however, glucose, blood urea nitrogen, and creatine kinase (CK) levels stood out as abnormal. CK levels are commonly used in conjunction with muscle pain and/or myoglobinurea …
Unfortunately, none of the biomarkers assessed were indicative of passing training, however, glucose, blood urea nitrogen, and creatine …
Dantrolene. A review of its pharmacodynamic and pharmacokinetic properties and therapeutic use in malignant hyperthermia, the neuroleptic malignant syndrome and an update of its use in muscle spasticity.
Ward A, Chaffman MO, Sorkin EM. Ward A, et al. Drugs. 1986 Aug;32(2):130-68. doi: 10.2165/00003495-198632020-00003. Drugs. 1986. PMID: 3527659 Review.
There is a rapid resolution of hyperthermia, dysrhythmias, muscle rigidity, tachycardia, hypercapnia, mottled or cyanotic skin, and metabolic acidosis, and a slower normalisation of myoglobinuria and elevated serum creatine phosphokinase levels. In patients w …
There is a rapid resolution of hyperthermia, dysrhythmias, muscle rigidity, tachycardia, hypercapnia, mottled or cyanotic skin, and metaboli …
Urinary Metabolites Diagnostic and Prognostic of Intrahepatic Cholangiocarcinoma.
Haznadar M, Diehl CM, Parker AL, Krausz KW, Bowman ED, Rabibhadana S, Forgues M, Bhudhisawasdi V, Gonzalez FJ, Mahidol C, Budhu A, Wang XW, Ruchirawat M, Harris CC. Haznadar M, et al. Cancer Epidemiol Biomarkers Prev. 2019 Oct;28(10):1704-1711. doi: 10.1158/1055-9965.EPI-19-0453. Epub 2019 Jul 29. Cancer Epidemiol Biomarkers Prev. 2019. PMID: 31358519 Free PMC article.
High levels of CR were associated with poorer prognosis in ICC. CONCLUSIONS: Four metabolites are significantly increased in HCC and ICC and are robust at classifying ICC in combination with the clinically utilized marker CA19-9. IMPACT: Noninvasive urinary metaboli …
High levels of CR were associated with poorer prognosis in ICC. CONCLUSIONS: Four metabolites are significantly increased in HCC and …
Urinary Mitochondrial DNA Levels Identify Acute Kidney Injury in Surgical Critical Illness Patients.
Hu Q, Ren J, Wu J, Li G, Wu X, Liu S, Wang G, Gu G, Ren H, Hong Z, Li J. Hu Q, et al. Shock. 2017 Jul;48(1):11-17. doi: 10.1097/SHK.0000000000000830. Shock. 2017. PMID: 28060212
RESULTS: MtDNA were expressed as PCR threshold cycle (Tc) number. Lower Tc indicated increased urinary mtDNA concentration. The baseline UmtDNA levels were elevated in SICU patients especially in AKI patients, compared with that in healthy controls. ...CONCLU …
RESULTS: MtDNA were expressed as PCR threshold cycle (Tc) number. Lower Tc indicated increased urinary mtDNA concentration. The basel …
Urinary Metabolite Risk Biomarkers of Lung Cancer: A Prospective Cohort Study.
Haznadar M, Cai Q, Krausz KW, Bowman ED, Margono E, Noro R, Thompson MD, Mathé EA, Munro HM, Steinwandel MD, Gonzalez FJ, Blot WJ, Harris CC. Haznadar M, et al. Cancer Epidemiol Biomarkers Prev. 2016 Jun;25(6):978-86. doi: 10.1158/1055-9965.EPI-15-1191. Epub 2016 Mar 24. Cancer Epidemiol Biomarkers Prev. 2016. PMID: 27013655 Free PMC article.
METHODS: While seeking to identify stable and reproducible biomarkers in noninvasively collected biofluids, we assessed whether previously identified metabolite urinary lung cancer biomarkers, creatine riboside (CR), N-acetylneuraminic acid (NANA), cortisol sulfate, …
METHODS: While seeking to identify stable and reproducible biomarkers in noninvasively collected biofluids, we assessed whether previously i …
Heterotopic ossification mimicking infection in patients with traumatic spinal cord injury.
Citak M, Grasmücke D, Salber J, Cruciger O, Meindl R, Schildhauer TA, Aach M. Citak M, et al. Technol Health Care. 2016;24(1):87-91. doi: 10.3233/THC-151070. Technol Health Care. 2016. PMID: 26409557
CT scans of the thorax, abdomen and pelvis revealed no further pathologies besides the heterotopic ossification. Urinary tract infections were ruled out, using urine tests as a standard procedure in all cases. CONCLUSIONS: Elevated levels of serum CRP, …
CT scans of the thorax, abdomen and pelvis revealed no further pathologies besides the heterotopic ossification. Urinary tract …
Noninvasive urinary metabolomic profiling identifies diagnostic and prognostic markers in lung cancer.
Mathé EA, Patterson AD, Haznadar M, Manna SK, Krausz KW, Bowman ED, Shields PG, Idle JR, Smith PB, Anami K, Kazandjian DG, Hatzakis E, Gonzalez FJ, Harris CC. Mathé EA, et al. Cancer Res. 2014 Jun 15;74(12):3259-70. doi: 10.1158/0008-5472.CAN-14-0109. Epub 2014 Apr 15. Cancer Res. 2014. PMID: 24736543 Free PMC article.
Creatine riboside (IUPAC name: 2-{2-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)-oxolan-2-yl]-1-methylcarbamimidamido}acetic acid), a novel molecule identified in this study, and N-acetylneuraminic acid (NANA) were each significantly (P < 0.00001) elevated in n …
Creatine riboside (IUPAC name: 2-{2-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)-oxolan-2-yl]-1-methylcarbamimidamido}acetic acid), …
A case of myopathy and markedly elevated creatine kinase levels with hypocalcemia, hypomagnesemia, and hyposelenemia due to short bowel syndrome after rectal cancer resection.
Katayama T, Takahashi K, Yahara O, Yamada T. Katayama T, et al. Rinsho Shinkeigaku. 2023 May 27;63(5):286-290. doi: 10.5692/clinicalneurol.cn-001814. Epub 2023 Apr 25. Rinsho Shinkeigaku. 2023. PMID: 37100625
A 66-year-old Japanese man was referred to our hospital with myalgia and muscle weakness. He had a history of rectal cancer, which invaded into the urinary bladder and ileum and was treated with chemotherapy, radiotherapy, resection of the rectum, colostomy, and ileal cond …
A 66-year-old Japanese man was referred to our hospital with myalgia and muscle weakness. He had a history of rectal cancer, which invaded i …
63 results