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Quoted phrase not found in phrase index: "Endocannabinoid enhancer"
Page 1
Current Aspects of the Endocannabinoid System and Targeted THC and CBD Phytocannabinoids as Potential Therapeutics for Parkinson's and Alzheimer's Diseases: a Review.
Cooray R, Gupta V, Suphioglu C. Cooray R, et al. Mol Neurobiol. 2020 Nov;57(11):4878-4890. doi: 10.1007/s12035-020-02054-6. Epub 2020 Aug 19. Mol Neurobiol. 2020. PMID: 32813239 Free PMC article. Review.
This literature review aims to provide a collection of published work on PD and AD and current uses of endocannabinoid system (ECS) as a potential drug target for neurodegeneration. ...AD characterised by extracellular deposits of amyloid beta-senile plaques and neurofibri …
This literature review aims to provide a collection of published work on PD and AD and current uses of endocannabinoid system (ECS) a …
A microbiome-dependent gut-brain pathway regulates motivation for exercise.
Dohnalová L, Lundgren P, Carty JRE, Goldstein N, Wenski SL, Nanudorn P, Thiengmag S, Huang KP, Litichevskiy L, Descamps HC, Chellappa K, Glassman A, Kessler S, Kim J, Cox TO, Dmitrieva-Posocco O, Wong AC, Allman EL, Ghosh S, Sharma N, Sengupta K, Cornes B, Dean N, Churchill GA, Khurana TS, Sellmyer MA, FitzGerald GA, Patterson AD, Baur JA, Alhadeff AL, Helfrich EJN, Levy M, Betley JN, Thaiss CA. Dohnalová L, et al. Nature. 2022 Dec;612(7941):739-747. doi: 10.1038/s41586-022-05525-z. Epub 2022 Dec 14. Nature. 2022. PMID: 36517598
Here, we report on the discovery of a gut-brain connection in mice that enhances exercise performance by augmenting dopamine signalling during physical activity. ...Our study also suggests that interoceptomimetic molecules that stimulate the transmission of gut-derived sig …
Here, we report on the discovery of a gut-brain connection in mice that enhances exercise performance by augmenting dopamine signalli …
Effect of gut microbiota on depressive-like behaviors in mice is mediated by the endocannabinoid system.
Chevalier G, Siopi E, Guenin-Macé L, Pascal M, Laval T, Rifflet A, Boneca IG, Demangel C, Colsch B, Pruvost A, Chu-Van E, Messager A, Leulier F, Lepousez G, Eberl G, Lledo PM. Chevalier G, et al. Nat Commun. 2020 Dec 11;11(1):6363. doi: 10.1038/s41467-020-19931-2. Nat Commun. 2020. PMID: 33311466 Free PMC article.
The cellular and behavioral alterations observed in recipient mice were accompanied by a decrease in the endocannabinoid (eCB) signaling due to lower peripheral levels of fatty acid precursors of eCB ligands. The adverse effects of UCMS-transferred microbiota were alleviat …
The cellular and behavioral alterations observed in recipient mice were accompanied by a decrease in the endocannabinoid (eCB) signal …
Mechanisms of endocannabinoid transport in the brain.
Kaczocha M, Haj-Dahmane S. Kaczocha M, et al. Br J Pharmacol. 2022 Sep;179(17):4300-4310. doi: 10.1111/bph.15469. Epub 2021 May 27. Br J Pharmacol. 2022. PMID: 33786823 Free PMC article. Review.
Extensive research conducted over the last few decades has considerably enhanced our understanding of the molecular mechanisms and physiological functions of the endocannabinoid system. ...While the detailed mechanisms by which endocannabinoids gate synaptic …
Extensive research conducted over the last few decades has considerably enhanced our understanding of the molecular mechanisms and ph …
Endocannabinoid Mechanisms Influencing Nausea.
Sticht MA, Rock EM, Limebeer CL, Parker LA. Sticht MA, et al. Int Rev Neurobiol. 2015;125:127-62. doi: 10.1016/bs.irn.2015.09.001. Epub 2015 Nov 6. Int Rev Neurobiol. 2015. PMID: 26638766 Review.
Indeed, when nausea becomes conditionally elicited by the cues associated with chemotherapy treatment, known as anticipatory nausea (AN), currently available antiemetics are largely ineffective. Considerable evidence demonstrates that the endocannabinoid system regulates n …
Indeed, when nausea becomes conditionally elicited by the cues associated with chemotherapy treatment, known as anticipatory nausea (AN), cu …
Endocannabinoid Signaling and the Hypothalamic-Pituitary-Adrenal Axis.
Hillard CJ, Beatka M, Sarvaideo J. Hillard CJ, et al. Compr Physiol. 2016 Dec 6;7(1):1-15. doi: 10.1002/cphy.c160005. Compr Physiol. 2016. PMID: 28134998 Free PMC article. Review.
We provide a brief introduction to the endocannabinoid signaling system and its role in synaptic plasticity. ...We present a hypothesis that the inhibitory arm has high endocannabinoid tone and also serves to enhance recovery to baseline following stress, whi …
We provide a brief introduction to the endocannabinoid signaling system and its role in synaptic plasticity. ...We present a hypothes …
Endocannabinoid system and aggression across animal species.
Migliaro M, Ruiz-Contreras AE, Herrera-Solís A, Méndez-Díaz M, Prospéro-García OE. Migliaro M, et al. Neurosci Biobehav Rev. 2023 Oct;153:105375. doi: 10.1016/j.neubiorev.2023.105375. Epub 2023 Aug 27. Neurosci Biobehav Rev. 2023. PMID: 37643683 Review.
This narrative review article summarizes the current state of knowledge regarding the relationship between the endocannabinoid system (ECS) and aggression across multiple vertebrate species. Experimental evidence indicates that acute administration of phytocannabinoids, sy …
This narrative review article summarizes the current state of knowledge regarding the relationship between the endocannabinoid system …
Endocannabinoid Signalling in Atherosclerosis and Related Metabolic Complications.
Guillamat-Prats R, Rami M, Herzig S, Steffens S. Guillamat-Prats R, et al. Thromb Haemost. 2019 Apr;119(4):567-575. doi: 10.1055/s-0039-1678738. Epub 2019 Feb 15. Thromb Haemost. 2019. PMID: 30769363 Review.
Moreover, elevated circulating endocannabinoid levels are also prevalent in atherosclerosis. The pathophysiological increase of endocannabinoid levels is due to an altered expression of endocannabinoid synthesizing and degrading enzymes induced by inflammator …
Moreover, elevated circulating endocannabinoid levels are also prevalent in atherosclerosis. The pathophysiological increase of en …
Enhanced endocannabinoid tone as a potential target of pharmacotherapy.
Toczek M, Malinowska B. Toczek M, et al. Life Sci. 2018 Jul 1;204:20-45. doi: 10.1016/j.lfs.2018.04.054. Epub 2018 May 2. Life Sci. 2018. PMID: 29729263 Review.
In this paper, we discuss multiple pathways of endocannabinoid metabolism, changes in endocannabinoid levels across numerous human diseases and corresponding experimental models, pharmacological strategies for enhancing endocannabinoid tone and potenti …
In this paper, we discuss multiple pathways of endocannabinoid metabolism, changes in endocannabinoid levels across numerous h …
Anxiolytic effects of endocannabinoid enhancing compounds: A systematic review and meta-analysis.
Kwee CMB, Leen NA, Van der Kamp RC, Van Lissa CJ, Cath DC, Groenink L, Baas JMP. Kwee CMB, et al. Eur Neuropsychopharmacol. 2023 Jul;72:79-94. doi: 10.1016/j.euroneuro.2023.04.001. Epub 2023 Apr 23. Eur Neuropsychopharmacol. 2023. PMID: 37094409 Free article. Review.
The endocannabinoid system is a promising candidate for anxiolytic therapy, but translation to the clinic has been lagging. We meta-analyzed the evidence for anxiety-reduction by compounds that facilitate endocannabinoid signaling in humans and animals. To identify …
The endocannabinoid system is a promising candidate for anxiolytic therapy, but translation to the clinic has been lagging. We meta-a …
1,825 results