Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My NCBI Filters

Results by year

Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1968 1
1972 2
1973 1
1974 1
1975 6
1976 8
1977 6
1978 7
1979 7
1980 2
1981 15
1982 6
1983 4
1984 5
1985 5
1986 3
1989 1
1991 1
1993 1
1995 2
1999 2
2000 2
2002 1
2003 1
2005 2
2006 2
2007 1
2008 15
2009 3
2010 1
2011 2
2012 2
2013 2
2014 9
2015 9
2016 5
2017 15
2018 7
2019 5
2020 14
2021 22
2022 18
2023 29
2024 15

Text availability

Article attribute

Article type

Publication date

Search Results

249 results

Results by year

Filters applied: . Clear all
Page 1
Estetrol/Drospirenone: A Review in Oral Contraception.
Lee A, Syed YY. Lee A, et al. Drugs. 2022 Jul;82(10):1117-1125. doi: 10.1007/s40265-022-01738-8. Epub 2022 Jul 4. Drugs. 2022. PMID: 35781795 Free PMC article. Review.
Estetrol/drospirenone is a combined oral contraceptive (COC) with a plant-synthesised foetal oestrogen (estetrol) and a well-established progestin (drospirenone). ...The low oestrogenicity of estetrol may potentially contribute to reduced thrombotic risk. …
Estetrol/drospirenone is a combined oral contraceptive (COC) with a plant-synthesised foetal oestrogen (estetrol) and a well-e …
Estetrol: A New Choice for Contraception.
Fruzzetti F, Fidecicchi T, Montt Guevara MM, Simoncini T. Fruzzetti F, et al. J Clin Med. 2021 Nov 29;10(23):5625. doi: 10.3390/jcm10235625. J Clin Med. 2021. PMID: 34884326 Free PMC article. Review.
Estetrol (E4) is a natural estrogenic steroid that is normally produced by human fetal liver. ...
Estetrol (E4) is a natural estrogenic steroid that is normally produced by human fetal liver. ...
A novel estetrol-containing combined oral contraceptive: European expert panel review.
Gemzell-Danielsson Kristina, Cagnacci Angelo, Chabbert-Buffet Nathalie, Douxfils Jonathan, Foidart Jean-Michel, Kubba Ali, Lasa Luis Ignacio Lete, Mansour Diana, Neulen Joseph, Neves Jaoquim, Palma Fátima, Römer Thomas, Ski Robert Spaczy, Tóth Vera. Gemzell-Danielsson Kristina, et al. Ceska Gynekol. 2022;87(6):440-452. Ceska Gynekol. 2022. PMID: 36543594 Review. English.
PURPOSE: Despite considerable advances in recently developed combined oral contraceptives (COCs), resulting in lower rates of adverse events while maintaining contraceptive efficacy, there is interest in further innovation. MATERIALS AND METHODS: Estetrol (E4), a native oe …
PURPOSE: Despite considerable advances in recently developed combined oral contraceptives (COCs), resulting in lower rates of adverse events …
Estetrol and Mammary Gland: Friends or Foes?
Gallez A, Dias Da Silva I, Wuidar V, Foidart JM, Péqueux C. Gallez A, et al. J Mammary Gland Biol Neoplasia. 2021 Sep;26(3):297-308. doi: 10.1007/s10911-021-09497-0. Epub 2021 Aug 31. J Mammary Gland Biol Neoplasia. 2021. PMID: 34463898 Free PMC article. Review.
Estrogen receptor alpha functions as the principal mediator of estrogenic action in most of these tissues. Estetrol (E4) is a native fetal estrogen with selective tissue actions that is currently approved for use as the estrogen component in a combined oral contraceptive a …
Estrogen receptor alpha functions as the principal mediator of estrogenic action in most of these tissues. Estetrol (E4) is a native …
Estetrol-drospirenone combination oral contraceptive: North American phase 3 efficacy and safety results.
Creinin MD, Westhoff CL, Bouchard C, Chen MJ, Jensen JT, Kaunitz AM, Achilles SL, Foidart JM, Archer DF. Creinin MD, et al. Contraception. 2021 Sep;104(3):222-228. doi: 10.1016/j.contraception.2021.05.002. Epub 2021 May 15. Contraception. 2021. PMID: 34000251 Free article. Clinical Trial.
OBJECTIVE: To assess efficacy, cycle control, and safety of an oral contraceptive containing estetrol (E4) 15 mg and drospirenone (DRSP) 3 mg. STUDY DESIGN: Women aged 16 to 50 years with a body mass index 35 kg/m(2) enrolled in this multicenter, open-label, 13-cycle, phas …
OBJECTIVE: To assess efficacy, cycle control, and safety of an oral contraceptive containing estetrol (E4) 15 mg and drospirenone (DR …
Estetrol: From Preclinical to Clinical Pharmacology and Advances in the Understanding of the Molecular Mechanism of Action.
Gérard C, Foidart JM. Gérard C, et al. Drugs R D. 2023 Jun;23(2):77-92. doi: 10.1007/s40268-023-00419-5. Epub 2023 May 3. Drugs R D. 2023. PMID: 37133685 Free PMC article. Review.
Estetrol (E4) is the most recently described natural estrogen. It is produced by the human fetal liver during pregnancy and its physiological function remains unclear. ...
Estetrol (E4) is the most recently described natural estrogen. It is produced by the human fetal liver during pregnancy and its physi …
Drospirenone and estetrol: evaluation of a newly approved novel oral contraceptive.
Nelson AL. Nelson AL. Expert Opin Pharmacother. 2023 Sep-Dec;24(16):1757-1764. doi: 10.1080/14656566.2023.2247979. Epub 2023 Sep 11. Expert Opin Pharmacother. 2023. PMID: 37691580 Review.
INTRODUCTION: Estetrol (E4) is a native estrogen produced only by the fetal liver during pregnancy. ...In the future, estetrol may be the estrogen of choice if subsequent evidence verifies that it reduces the risks associated with current estrogens, such as venous t …
INTRODUCTION: Estetrol (E4) is a native estrogen produced only by the fetal liver during pregnancy. ...In the future, estetrol …
Endocrine and metabolic effects of an oral contraceptive containing estetrol and drospirenone.
Klipping C, Duijkers I, Mawet M, Maillard C, Bastidas A, Jost M, Foidart JM. Klipping C, et al. Contraception. 2021 Apr;103(4):213-221. doi: 10.1016/j.contraception.2021.01.001. Epub 2021 Jan 9. Contraception. 2021. PMID: 33428907 Free article. Clinical Trial.
OBJECTIVES: To evaluate the effect on endocrine and metabolic parameters of a new combined oral contraceptive (COC) containing estetrol (E4) and drospirenone (DRSP). STUDY DESIGN: Randomized, open-label, controlled, 3-arm, parallel study. ...
OBJECTIVES: To evaluate the effect on endocrine and metabolic parameters of a new combined oral contraceptive (COC) containing estetrol …
Estetrol-Drospirenone combination oral contraceptive: a clinical study of contraceptive efficacy, bleeding pattern and safety in Europe and Russia.
Gemzell-Danielsson K, Apter D, Zatik J, Weyers S, Piltonen T, Suturina L, Apolikhina I, Jost M, Creinin MD, Foidart JM. Gemzell-Danielsson K, et al. BJOG. 2022 Jan;129(1):63-71. doi: 10.1111/1471-0528.16840. Epub 2021 Aug 9. BJOG. 2022. PMID: 34245666 Free PMC article. Clinical Trial.
OBJECTIVES: To assess the contraceptive efficacy, bleeding pattern and safety of a combined oral contraceptive containing estetrol (E4) 15 mg and drospirenone (DRSP) 3 mg. DESIGN: Multicenter, open-label, phase 3 trial. ...
OBJECTIVES: To assess the contraceptive efficacy, bleeding pattern and safety of a combined oral contraceptive containing estetrol (E …
A novel estetrol-containing combined oral contraceptive: European expert panel review.
Gemzell-Danielsson K, Cagnacci A, Chabbert-Buffet N, Douxfils J, Foidart JM, Kubba A, Lete Lasa LI, Mansour D, Neulen J, Neves J, Palma F, Römer T, Spaczyński R, Tóth V. Gemzell-Danielsson K, et al. Eur J Contracept Reprod Health Care. 2022 Oct;27(5):373-383. doi: 10.1080/13625187.2022.2093850. Epub 2022 Jul 21. Eur J Contracept Reprod Health Care. 2022. PMID: 35862627 Review.
PURPOSE: Despite considerable advances in recently developed combined oral contraceptives (COCs), resulting in lower rates of adverse events while maintaining contraceptive efficacy, there is interest in further innovation. MATERIALS AND METHODS: Estetrol (E4), a native oe …
PURPOSE: Despite considerable advances in recently developed combined oral contraceptives (COCs), resulting in lower rates of adverse events …
249 results