Comprehensive genetic analysis of pediatric germ cell tumors identifies potential drug targets.
Kubota Y, Seki M, Kawai T, Isobe T, Yoshida M, Sekiguchi M, Kimura S, Watanabe K, Sato-Otsubo A, Yoshida K, Suzuki H, Kataoka K, Fujii Y, Shiraishi Y, Chiba K, Tanaka H, Hiwatari M, Oka A, Hayashi Y, Miyano S, Ogawa S, Hata K, Tanaka Y, Takita J.
Kubota Y, et al.
Commun Biol. 2020 Sep 30;3(1):544. doi: 10.1038/s42003-020-01267-8.
Commun Biol. 2020.
PMID: 32999426
Free PMC article.
Pluripotent genes were also highly expressed in embryonal carcinomas. These genes may play essential roles in embryonal carcinomas given that their binding sites are hypomethylated. ...Based on our results, we suggest that KIT, TNFRSF8, and ERBB4 may be suitable tar …
Pluripotent genes were also highly expressed in embryonal carcinomas. These genes may play essential roles in embryonal carcin …