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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
2001 3
2002 5
2003 6
2004 6
2005 9
2006 4
2007 10
2008 11
2009 5
2010 9
2011 7
2012 8
2013 13
2014 8
2015 10
2016 7
2017 7
2018 5
2019 3
2020 11
2021 7
2022 7
2023 1
2024 2

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148 results

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Page 1
Exploiting synthetic lethality to target BRCA1/2-deficient tumors: where we stand.
Patel PS, Algouneh A, Hakem R. Patel PS, et al. Oncogene. 2021 Apr;40(17):3001-3014. doi: 10.1038/s41388-021-01744-2. Epub 2021 Mar 14. Oncogene. 2021. PMID: 33716297 Review.
Here, we explore other identified synthetic lethal interactors of BRCA1/2, including DNA polymerase theta (POLQ), Fanconi anemia complementation group D2 (FANDC2), radiation sensitive 52 (RAD52), Flap structure-specific endonuclease 1 (FEN1), an …
Here, we explore other identified synthetic lethal interactors of BRCA1/2, including DNA polymerase theta (POLQ), Fanconi anemia …
Constitutive role of the Fanconi anemia D2 gene in the replication stress response.
Tian Y, Shen X, Wang R, Klages-Mundt NL, Lynn EJ, Martin SK, Ye Y, Gao M, Chen J, Schlacher K, Li L. Tian Y, et al. J Biol Chem. 2017 Dec 8;292(49):20184-20195. doi: 10.1074/jbc.M117.814780. Epub 2017 Oct 11. J Biol Chem. 2017. PMID: 29021208 Free PMC article.
In response to DNA cross-linking damage, the Fanconi anemia (FA) core complex activates the FA pathway by monoubiquitinating Fanconi anemia complementation group D2 (FANCD2) for the initiation of the nucleolytic processing of the DNA cross-links …
In response to DNA cross-linking damage, the Fanconi anemia (FA) core complex activates the FA pathway by monoubiquitinating Fanconi …
Fanconi anemia complementation group D2 promotes sensitivity of endometrial cancer cells to chemotherapeutic agents by inhibiting the ferroptosis pathway.
Lin HH, Zeng WH, Yang HK, Huang LS, Pan R, Lei NX. Lin HH, et al. BMC Womens Health. 2024 Jan 13;24(1):41. doi: 10.1186/s12905-023-02857-4. BMC Womens Health. 2024. PMID: 38218826 Free PMC article.
BACKGROUND: Resistance can develop during treatment of advanced endometrial cancer (EC), leading to unsatisfactory results. Fanconi anemia complementation group D2 (Fancd2) has been shown to be closely related to drug resistance in cancer cells. …
BACKGROUND: Resistance can develop during treatment of advanced endometrial cancer (EC), leading to unsatisfactory results. Fanconi …
High content drug screening for Fanconi anemia therapeutics.
Montanuy H, Camps-Fajol C, Carreras-Puigvert J, Häggblad M, Lundgren B, Aza-Carmona M, Helleday T, Minguillón J, Surrallés J. Montanuy H, et al. Orphanet J Rare Dis. 2020 Jun 30;15(1):170. doi: 10.1186/s13023-020-01437-1. Orphanet J Rare Dis. 2020. PMID: 32605631 Free PMC article.
TFG-maintaining stability of overlooked FANCD2 confers early DNA-damage response.
Ma C, Hokutan K, Shen Y, Nepal M, Kim JH, Zhang J, Fei P. Ma C, et al. Aging (Albany NY). 2020 Oct 24;12(20):20268-20284. doi: 10.18632/aging.103782. Epub 2020 Oct 24. Aging (Albany NY). 2020. PMID: 33099537 Free PMC article.
Emerging Fanconi Anemia (FA) signaling in the field of cancer research annotates the extreme importance of its center player, Fanconi Anemia complementation group D2 (FANCD2) in protecting human cells from going awry. ...
Emerging Fanconi Anemia (FA) signaling in the field of cancer research annotates the extreme importance of its center player, Fanconi …
148 results