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Page 1
FANCL supports Parkin-mediated mitophagy in a ubiquitin ligase-independent manner.
Beesetti S, Sirasanagandla S, Sakurada SM, Pruett-Miller SM, Sumpter R Jr, Levine B, Potts MB. Beesetti S, et al. Biochim Biophys Acta Mol Basis Dis. 2022 Sep 1;1868(9):166453. doi: 10.1016/j.bbadis.2022.166453. Epub 2022 May 26. Biochim Biophys Acta Mol Basis Dis. 2022. PMID: 35644338 Free PMC article.
Constitutive role of the Fanconi anemia D2 gene in the replication stress response.
Tian Y, Shen X, Wang R, Klages-Mundt NL, Lynn EJ, Martin SK, Ye Y, Gao M, Chen J, Schlacher K, Li L. Tian Y, et al. J Biol Chem. 2017 Dec 8;292(49):20184-20195. doi: 10.1074/jbc.M117.814780. Epub 2017 Oct 11. J Biol Chem. 2017. PMID: 29021208 Free PMC article.
To address this question, we generated cellular knock-out models of FA core complex components and FANCD2 and found that FANCD2-null mutants display higher levels of spontaneous chromosomal damage and hypersensitivity to replication-blocking lesions than Fanconi anemia …
To address this question, we generated cellular knock-out models of FA core complex components and FANCD2 and found that FANCD2-null mutants …
Massively parallel sequencing, aCGH, and RNA-Seq technologies provide a comprehensive molecular diagnosis of Fanconi anemia.
Chandrasekharappa SC, Lach FP, Kimble DC, Kamat A, Teer JK, Donovan FX, Flynn E, Sen SK, Thongthip S, Sanborn E, Smogorzewska A, Auerbach AD, Ostrander EA; NISC Comparative Sequencing Program. Chandrasekharappa SC, et al. Blood. 2013 May 30;121(22):e138-48. doi: 10.1182/blood-2012-12-474585. Epub 2013 Apr 23. Blood. 2013. PMID: 23613520 Free PMC article.
22 results