Double heterozygous pathogenic mutations in KIF3C and ZNF513 cause hereditary gingival fibromatosis.
Chen J, Xu X, Chen S, Lu T, Zheng Y, Gan Z, Shen Z, Ma S, Wang D, Su L, He F, Shang X, Xu H, Chen D, Zhang L, Xiong F.
Chen J, et al.
Int J Oral Sci. 2023 Sep 26;15(1):46. doi: 10.1038/s41368-023-00244-1.
Int J Oral Sci. 2023.
PMID: 37752101
Free PMC article.
Hereditary gingival fibromatosis (HGF) is a rare inherited condition with fibromatoid hyperplasia of the gingival tissue that exhibits great genetic heterogeneity. ...ZNF513, a transcription factor, binds to KIF3C exon 1 and participates in the positive regul …
Hereditary gingival fibromatosis (HGF) is a rare inherited condition with fibromatoid hyperplasia of the gingival tissu …