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Quoted phrase not found in phrase index: "Focal impaired awareness motor seizure"
Page 1
Focal epilepsies: Update on diagnosis and classification.
Nascimento FA, Friedman D, Peters JM, Bensalem-Owen MK, Cendes F, Rampp S, Wirrell E, Blümcke I, Tatum W, Beniczky S. Nascimento FA, et al. Epileptic Disord. 2023 Feb;25(1):1-17. doi: 10.1002/epd2.20045. Epub 2023 Apr 17. Epileptic Disord. 2023. PMID: 36938903
Focal seizures, defined as those that originate within networks limited to one hemisphere, are primarily subdivided into focal aware, focal impaired awareness, and focal to bilateral tonic-clonic seizures. ...In child …
Focal seizures, defined as those that originate within networks limited to one hemisphere, are primarily subdivided into fo …
Safety and efficacy of adjunctive cenobamate (YKP3089) in patients with uncontrolled focal seizures: a multicentre, double-blind, randomised, placebo-controlled, dose-response trial.
Krauss GL, Klein P, Brandt C, Lee SK, Milanov I, Milovanovic M, Steinhoff BJ, Kamin M. Krauss GL, et al. Lancet Neurol. 2020 Jan;19(1):38-48. doi: 10.1016/S1474-4422(19)30399-0. Epub 2019 Nov 14. Lancet Neurol. 2020. PMID: 31734103 Clinical Trial.
The primary efficacy outcomes were percentage change in 28-day focal seizure frequency (focal aware motor, focal impaired awareness, or focal to bilateral tonic-clonic seizures) from baseline analysed in the mo …
The primary efficacy outcomes were percentage change in 28-day focal seizure frequency (focal aware motor …
Sudden unexpected death in epilepsy during cenobamate clinical development.
Rosenfeld WE, Ferrari L, Kerr WT, Sperling MR. Rosenfeld WE, et al. Epilepsia. 2023 Aug;64(8):2108-2115. doi: 10.1111/epi.17662. Epub 2023 Jun 5. Epilepsia. 2023. PMID: 37219391
METHODS: We retrospectively analyzed deaths among all adults with uncontrolled focal (focal to bilateral tonic-clonic [FBTC], focal impaired awareness, focal aware) or primary generalized tonic-clonic (PGTC) seizures who rec …
METHODS: We retrospectively analyzed deaths among all adults with uncontrolled focal (focal to bilateral tonic-clonic [FBTC], …
Randomized phase 2 study of adjunctive cenobamate in patients with uncontrolled focal seizures.
Chung SS, French JA, Kowalski J, Krauss GL, Lee SK, Maciejowski M, Rosenfeld WE, Sperling MR, Mizne S, Kamin M. Chung SS, et al. Neurology. 2020 Jun 2;94(22):e2311-e2322. doi: 10.1212/WNL.0000000000009530. Epub 2020 May 14. Neurology. 2020. PMID: 32409485 Free PMC article. Clinical Trial.
Focal seizures with motor component, impaired awareness, and focal to bilateral tonic-clonic seizures were significantly reduced with cenobamate vs placebo. ...CONCLUSION: Adjunctive treatment with cenobamate 200 mg/d significantly …
Focal seizures with motor component, impaired awareness, and focal to bilateral tonic-clonic se …
Consciousness of seizures and consciousness during seizures: are they related?
Detyniecki K, Blumenfeld H. Detyniecki K, et al. Epilepsy Behav. 2014 Jan;30:6-9. doi: 10.1016/j.yebeh.2013.09.018. Epub 2013 Oct 12. Epilepsy Behav. 2014. PMID: 24126026 Free PMC article. Review.
Recent advances have been made in the network mechanisms underlying impairment of consciousness during seizures. However, less is known about patient awareness of their own seizures. Studying patient reports or documentation of their seizures is …
Recent advances have been made in the network mechanisms underlying impairment of consciousness during seizures. However, less …
Evaluating consciousness and awareness during focal seizures: responsiveness testing versus recall testing.
Contreras Ramirez V, Patedakis Litvinov B, Gunawardane NA, Zhao CW, Yotter C, Quraishi IH, Blumenfeld H. Contreras Ramirez V, et al. Epileptic Disord. 2022 Oct 1;24(5):899-905. doi: 10.1684/epd.2022.1472. Epileptic Disord. 2022. PMID: 35904040 Free PMC article.
OBJECTIVE: The current International League Against Epilepsy (ILAE) guidelines classify focal seizures based on awareness, defined as successful postictal recall of ictal experiences, and exclude the use of responsiveness during seizures for classifica …
OBJECTIVE: The current International League Against Epilepsy (ILAE) guidelines classify focal seizures based on awareness …
Duration of postictal impaired awareness after bilateral tonic-clonic seizures: EEG and patient characteristics.
Kanth KM, Zimmerman CS, Toprani SC, Seyal M. Kanth KM, et al. Epilepsy Behav. 2022 Mar;128:108576. doi: 10.1016/j.yebeh.2022.108576. Epub 2022 Feb 2. Epilepsy Behav. 2022. PMID: 35123240
Postictal agitation was more common in males (p = 0.023). SIGNIFICANCE: Focal seizures may impair awareness by active inhibition of subcortical arousal mechanisms. Focal seizures progressing to bilateral tonic-clonic seizures (BTCS …
Postictal agitation was more common in males (p = 0.023). SIGNIFICANCE: Focal seizures may impair awareness by a …
Anti-seizure medications and efficacy against focal to bilateral tonic-clonic seizures: A systematic review with relevance for SUDEP prevention.
Cutillo G, Tolba H, Hirsch LJ. Cutillo G, et al. Epilepsy Behav. 2021 Apr;117:107815. doi: 10.1016/j.yebeh.2021.107815. Epub 2021 Feb 26. Epilepsy Behav. 2021. PMID: 33640562 Review.
We conducted a systematic review of anti-seizure medications (ASMs) and their efficacy for the control of focal to bilateral tonic-clonic seizures (FBTCS). ...We searched different online databases for all the randomized, double-blinded, and placebo-controlle …
We conducted a systematic review of anti-seizure medications (ASMs) and their efficacy for the control of focal to bilateral t …
Seizure underreporting in LGI1 and CASPR2 antibody encephalitis.
Baumgartner T, Pitsch J, Olaciregui-Dague K, Hoppe C, Racz A, Rüber T, Becker A, von Wrede R, Surges R. Baumgartner T, et al. Epilepsia. 2022 Sep;63(9):e100-e105. doi: 10.1111/epi.17338. Epub 2022 Jul 4. Epilepsia. 2022. PMID: 35735209
Patients with anti-leucine-rich glioma-inactivated 1 protein (LGI1) or anti-contactin-associated protein 2 (CASPR2) antibody encephalitis typically present with frequent epileptic seizures. The seizures generally respond well to immunosuppressive therapy, and the lo …
Patients with anti-leucine-rich glioma-inactivated 1 protein (LGI1) or anti-contactin-associated protein 2 (CASPR2) antibody encephalitis ty …
Posterior Cingulate Epilepsy: A Systematic Review.
Pepin C, Brochu K, Lessard-Bonaventure P, Nguyen DK, Martineau L. Pepin C, et al. J Clin Neurophysiol. 2023 Sep 1;40(6):507-515. doi: 10.1097/WNP.0000000000000975. Epub 2023 Mar 15. J Clin Neurophysiol. 2023. PMID: 36930208
Impaired awareness during seizures was more frequently reported in PCE than in pMCE. As for ictal scalp EEG, epileptogenic abnormalities were poorly lateralized and did not localize the seizure onset zone. An ictal temporal involvement was only …
Impaired awareness during seizures was more frequently reported in PCE than in pMCE. As for ictal scalp EEG, epileptoge …
133 results