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19 results

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Page 1
Epidermolysis Bullosa: A Review of the Tissue-Engineered Skin Substitutes Used to Treat Wounds.
du Rand A, Hunt JMT, Feisst V, Sheppard HM. du Rand A, et al. Mol Diagn Ther. 2022 Nov;26(6):627-643. doi: 10.1007/s40291-022-00613-2. Epub 2022 Oct 17. Mol Diagn Ther. 2022. PMID: 36251245 Free PMC article. Review.
Skin wound healing is a crucial process for regenerating healthy skin and avoiding the undesired consequences associated with open skin wounds. For epidermolysis bullosa (EB), a debilitating group of fragile skin disorders currently without a cure, skin blistering c …
Skin wound healing is a crucial process for regenerating healthy skin and avoiding the undesired consequences associated with open skin woun …
Granzyme B in injury, inflammation, and repair.
Hiebert PR, Granville DJ. Hiebert PR, et al. Trends Mol Med. 2012 Dec;18(12):732-41. doi: 10.1016/j.molmed.2012.09.009. Epub 2012 Oct 22. Trends Mol Med. 2012. PMID: 23099058 Review.
Fragile skin and susceptibility to skin tearing are major problems among the elderly and can be complicated further by impaired wound healing. Non-healing wounds fail to progress through the normal stages of healing and enter a state of chronic inflammation featurin
Fragile skin and susceptibility to skin tearing are major problems among the elderly and can be complicated further by impaire
Topical Coconut Oil in Very Preterm Infants: An Open-Label Randomised Controlled Trial.
Strunk T, Pupala S, Hibbert J, Doherty D, Patole S. Strunk T, et al. Neonatology. 2018;113(2):146-151. doi: 10.1159/000480538. Epub 2017 Dec 1. Neonatology. 2018. PMID: 29197867 Clinical Trial.
BACKGROUND: The immature fragile skin of preterm infants represents an inadequate protective barrier. ...The neonatal skin condition was the primary outcome, and was assessed using the Neonatal Skin Condition Score (NSCS) on days 1, 7, 14, and 21. The number …
BACKGROUND: The immature fragile skin of preterm infants represents an inadequate protective barrier. ...The neonatal skin con …
Amplicon-based skin microbiome profiles collected by tape stripping with different adhesive film dressings: a comparative study.
Ogai K, Shibata K, Takahashi N, Ogura K, Okamoto S, Sugama J. Ogai K, et al. BMC Microbiol. 2021 Feb 18;21(1):54. doi: 10.1186/s12866-021-02122-4. BMC Microbiol. 2021. PMID: 33602131 Free PMC article.
BACKGROUND: Medical film dressings have been used to obtain skin microbiota for skin microbiome studies, although their adhesive force may be so strong that the skin could be injured when applied to those who have fragile skin, such as older people. Several products …
BACKGROUND: Medical film dressings have been used to obtain skin microbiota for skin microbiome studies, although their adhesive force may b …
Pressure Injury Risk Assessment and Prevention in Patients With COVID-19 in the Intensive Care Unit.
Alderden J, Kennerly SM, Cox J, Yap TL. Alderden J, et al. AACN Adv Crit Care. 2022 Jun 15;33(2):173-185. doi: 10.4037/aacnacc2022335. AACN Adv Crit Care. 2022. PMID: 35657764
BACKGROUND: Patients critically ill with COVID-19 are at risk for hospital-acquired pressure injury, including device-related pressure injury. METHODS: Braden Scale predictive validity was compared between patients with and without COVID-19, and a logistic regression model …
BACKGROUND: Patients critically ill with COVID-19 are at risk for hospital-acquired pressure injury, including device-related pressure injur …
The Presence of Scarring and Associated Morbidity in the Burn Model System National Database.
Goverman J, He W, Martello G, Whalen A, Bittner E, Schulz J, Gibran N, Herndon D, Suman O, Kowalske K, Meyer WJ, Ryan C, Schneider J. Goverman J, et al. Ann Plast Surg. 2019 Mar;82(3 Suppl 2):S162-S168. doi: 10.1097/SAP.0000000000001826. Ann Plast Surg. 2019. PMID: 30724824 Free PMC article.
The presence of scarring was not associated with Community Integration Questionnaire, Satisfaction with Life Scale, or Short Form 12 scores. Most patients reported symptoms associated with scarring at 2 years after burn, including dry or fragile skin, scars t …
The presence of scarring was not associated with Community Integration Questionnaire, Satisfaction with Life Scale, or Short Form 12 scor
An objective comparison of two pulse oximetry sensors with different adhesive systems on healthy human volunteers based on biophysical assessments.
Grove G, Houser T, Dove J, Moody D. Grove G, et al. Skin Res Technol. 2023 Jan;29(1):e13212. doi: 10.1111/srt.13212. Epub 2022 Nov 3. Skin Res Technol. 2023. PMID: 36329598 Free PMC article. Clinical Trial.
BACKGROUND: Medical Adhesive Related Skin Injuries can arise from topically applied medical devices, especially in those with fragile skin, including the elderly and premature infants. The purpose of this study was to compare gentleness and reapplication of two puls …
BACKGROUND: Medical Adhesive Related Skin Injuries can arise from topically applied medical devices, especially in those with fragile
Generalized atrophic benign epidermolysis bullosa.
Darling TN, Bauer JW, Hintner H, Yancey KB. Darling TN, et al. Adv Dermatol. 1997;13:87-119; discussion 120. Adv Dermatol. 1997. PMID: 9551142 Review.
The fact that patients deficient in type XVII collagen have fragile skin attests to the role of this protein in the adhesion of basal keratinocytes to epidermal BM. The severity of GABEB, however, is much less than that observed in patients with a complete de …
The fact that patients deficient in type XVII collagen have fragile skin attests to the role of this protein in the adhesion o …
Partial loss of epithelial phenotype in kindlin-1-deficient keratinocytes.
Qu H, Wen T, Pesch M, Aumailley M. Qu H, et al. Am J Pathol. 2012 Apr;180(4):1581-92. doi: 10.1016/j.ajpath.2012.01.005. Epub 2012 Feb 9. Am J Pathol. 2012. PMID: 22326752
Mutations in the gene encoding kindlin-1 are associated with Kindler syndrome, a recessively inherited disorder that is characterized by fragile skin. Functionally, a loss of kindlin-1 impairs the adhesion of basal keratinocytes to the extracellular matrix both in v …
Mutations in the gene encoding kindlin-1 are associated with Kindler syndrome, a recessively inherited disorder that is characterized by …
Increasing amount of amyloid are associated with the severity of clinical features in hereditary gelsolin (AGel) amyloidosis.
Pihlamaa T, Suominen S, Kiuru-Enari S, Tanskanen M. Pihlamaa T, et al. Amyloid. 2016 Dec;23(4):225-233. doi: 10.1080/13506129.2016.1238355. Epub 2016 Nov 23. Amyloid. 2016. PMID: 27879149
BACKGROUND: Patients with hereditary gelsolin (AGel) amyloidosis (HGA) present with hanging skin (cutis laxa) and bilateral cranial neuropathy, and require symptomatic plastic surgery. Our clinical observation of tissue fragility prompted us to design a prospective study. …
BACKGROUND: Patients with hereditary gelsolin (AGel) amyloidosis (HGA) present with hanging skin (cutis laxa) and bilateral cranial neuropat …
19 results