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732 results

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Quoted phrase not found in phrase index: "Frontotemporal dementia and/or amyotrophic lateral sclerosis 3"
Page 1
Music and dementia.
Baird A, Samson S. Baird A, et al. Prog Brain Res. 2015;217:207-35. doi: 10.1016/bs.pbr.2014.11.028. Epub 2015 Jan 31. Prog Brain Res. 2015. PMID: 25725917 Review.
There is an increasing incidence of dementia in our aging population, and consequently an urgent need to develop treatments and activities that may alleviate the symptoms of dementia. Accumulating evidence shows that persons with dementia enjoy music, and the …
There is an increasing incidence of dementia in our aging population, and consequently an urgent need to develop treatments and activ …
Psychedelic-inspired approaches for treating neurodegenerative disorders.
Saeger HN, Olson DE. Saeger HN, et al. J Neurochem. 2022 Jul;162(1):109-127. doi: 10.1111/jnc.15544. Epub 2021 Dec 5. J Neurochem. 2022. PMID: 34816433 Free PMC article. Review.
Moreover, evidence suggests that psychedelics and related compounds could prove useful for treating the behavioral and psychological symptoms of dementia (BPSD). While more research is needed to probe the effects of psychedelics in models of neurodegenerative diseases, the …
Moreover, evidence suggests that psychedelics and related compounds could prove useful for treating the behavioral and psychological symptom …
Use of Stimulants in Bipolar Disorder.
Perugi G, Vannucchi G, Bedani F, Favaretto E. Perugi G, et al. Curr Psychiatry Rep. 2017 Jan;19(1):7. doi: 10.1007/s11920-017-0758-x. Curr Psychiatry Rep. 2017. PMID: 28144880 Review.
Finally, MPH might be an option in some bipolar forms observed in psychiatric presentations of frontotemporal dementia and traumatic brain injury. In spite of these preliminary observations, the use of stimulants in bipolar patients is still controversial. ...
Finally, MPH might be an option in some bipolar forms observed in psychiatric presentations of frontotemporal dementia and tra …
Pharmacological Management of Apathy in Dementia.
Azhar L, Kusumo RW, Marotta G, Lanctôt KL, Herrmann N. Azhar L, et al. CNS Drugs. 2022 Feb;36(2):143-165. doi: 10.1007/s40263-021-00883-0. Epub 2022 Jan 10. CNS Drugs. 2022. PMID: 35006557 Review.
The objective of this review was to summarize the drugs that have been studied for apathy treatment in patients with dementia (specifically Alzheimer's disease [AD], Huntington's disease [HD] and Parkinson's disease [PD] dementia; dementia with Lewy bodies [D …
The objective of this review was to summarize the drugs that have been studied for apathy treatment in patients with dementia (specif …
Gut microbiota, circulating cytokines and dementia: a Mendelian randomization study.
Ji D, Chen WZ, Zhang L, Zhang ZH, Chen LJ. Ji D, et al. J Neuroinflammation. 2024 Jan 4;21(1):2. doi: 10.1186/s12974-023-02999-0. J Neuroinflammation. 2024. PMID: 38178103 Free PMC article.
METHODS: Gut microbiota, cytokines, and five dementia types, including Alzheimer's disease (AD), frontotemporal dementia (FTD), dementia with Lewy body (DLB), vascular dementia (VD), and Parkinson's disease dementia (PDD) were identified …
METHODS: Gut microbiota, cytokines, and five dementia types, including Alzheimer's disease (AD), frontotemporal dementia …
Trial of Pimavanserin in Dementia-Related Psychosis.
Tariot PN, Cummings JL, Soto-Martin ME, Ballard C, Erten-Lyons D, Sultzer DL, Devanand DP, Weintraub D, McEvoy B, Youakim JM, Stankovic S, Foff EP. Tariot PN, et al. N Engl J Med. 2021 Jul 22;385(4):309-319. doi: 10.1056/NEJMoa2034634. N Engl J Med. 2021. PMID: 34289275 Clinical Trial.
BACKGROUND: Patients with dementia due to neurodegenerative disease can have dementia-related psychosis. The effects of the oral 5-HT(2A) inverse agonist and antagonist pimavanserin on psychosis related to various causes of dementia are not clear. METHODS: We …
BACKGROUND: Patients with dementia due to neurodegenerative disease can have dementia-related psychosis. The effects of the or …
Memantine for dementia.
McShane R, Westby MJ, Roberts E, Minakaran N, Schneider L, Farrimond LE, Maayan N, Ware J, Debarros J. McShane R, et al. Cochrane Database Syst Rev. 2019 Mar 20;3(3):CD003154. doi: 10.1002/14651858.CD003154.pub6. Cochrane Database Syst Rev. 2019. PMID: 30891742 Free PMC article.
SELECTION CRITERIA: Double-blind, parallel group, placebo-controlled, randomised trials of memantine in people with dementia. DATA COLLECTION AND ANALYSIS: We pooled and analysed data from four clinical domains across different aetiologies and severities of …
SELECTION CRITERIA: Double-blind, parallel group, placebo-controlled, randomised trials of memantine in people with dementia. …
Functional recovery in new mouse models of ALS/FTLD after clearance of pathological cytoplasmic TDP-43.
Walker AK, Spiller KJ, Ge G, Zheng A, Xu Y, Zhou M, Tripathy K, Kwong LK, Trojanowski JQ, Lee VM. Walker AK, et al. Acta Neuropathol. 2015 Nov;130(5):643-60. doi: 10.1007/s00401-015-1460-x. Epub 2015 Jul 22. Acta Neuropathol. 2015. PMID: 26197969 Free PMC article.
Accumulation of phosphorylated cytoplasmic TDP-43 inclusions accompanied by loss of normal nuclear TDP-43 in neurons and glia of the brain and spinal cord are the molecular hallmarks of amyotrophic lateral sclerosis (ALS) and frontotemporal lobar degeneration (FTLD-TDP). H …
Accumulation of phosphorylated cytoplasmic TDP-43 inclusions accompanied by loss of normal nuclear TDP-43 in neurons and glia of the brain a …
Frontotemporal dementia.
Miller B, Llibre Guerra JJ. Miller B, et al. Handb Clin Neurol. 2019;165:33-45. doi: 10.1016/B978-0-444-64012-3.00003-4. Handb Clin Neurol. 2019. PMID: 31727221 Review.
Recent research reveals an overlap between frontotemporal dementia (FTD) and a variety of primary psychiatric disorders, challenging the artificial divisions between psychiatry and neurology. This chapter offers an overview of the clinical syndromes associate …
Recent research reveals an overlap between frontotemporal dementia (FTD) and a variety of primary psychiatric disorders, chall …
Latozinemab, a novel progranulin-elevating therapy for frontotemporal dementia.
Kurnellas M, Mitra A, Schwabe T, Paul R, Arrant AE, Roberson ED, Ward M, Yeh F, Long H, Rosenthal A. Kurnellas M, et al. J Transl Med. 2023 Jun 15;21(1):387. doi: 10.1186/s12967-023-04251-y. J Transl Med. 2023. PMID: 37322482 Free PMC article.
BACKGROUND: Heterozygous loss-of-function mutations in the progranulin (PGRN) gene (GRN) cause a reduction in PGRN and lead to the development of frontotemporal dementia (FTD-GRN). PGRN is a secreted lysosomal chaperone, immune regulator, and neuronal survival facto …
BACKGROUND: Heterozygous loss-of-function mutations in the progranulin (PGRN) gene (GRN) cause a reduction in PGRN and lead to the developme …
732 results