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IFN-γR/STAT1 signaling in recipient hematopoietic antigen-presenting cells suppresses graft-versus-host disease.
Lu C, Ma H, Song L, Wang H, Wang L, Li S, Lagana SM, Sepulveda AR, Hoebe K, Pan SS, Yang YG, Lentzsch S, Mapara MY. Lu C, et al. J Clin Invest. 2023 Feb 1;133(3):e125986. doi: 10.1172/JCI125986. J Clin Invest. 2023. PMID: 36445781 Free PMC article.
LPS-matured, BM-derived Ifngr1-/- Stat1-/- DCs (BMDCs) were more potent allogeneic stimulators and expressed increased levels of MHC II and costimulatory molecules. Similar effects were observed in human antigen-presenting cells (APCs) with knockdown of Stat1 by CRISPR/Cas …
LPS-matured, BM-derived Ifngr1-/- Stat1-/- DCs (BMDCs) were more potent allogeneic stimulators and expressed increased levels of MHC II and …
What predicts high risk acute graft-versus-host disease (GVHD) at onset?: identification of those at highest risk by a novel acute GVHD risk score.
MacMillan ML, DeFor TE, Weisdorf DJ. MacMillan ML, et al. Br J Haematol. 2012 Jun;157(6):732-41. doi: 10.1111/j.1365-2141.2012.09114.x. Epub 2012 Apr 6. Br J Haematol. 2012. PMID: 22486355 Free PMC article. Clinical Trial.
We compared the prognostic utility of the Minnesota (MN; modified from Consensus) versus Center for International Blood and Marrow Transplant Research (CIBMTR) GVHD organ stage-derived grading systems. As neither GVHD grading system optimally predicted outcom …
We compared the prognostic utility of the Minnesota (MN; modified from Consensus) versus Center for International Blood and Marrow Transplan …
Organ toxicity and quality of life after allogeneic bone marrow transplantation in pediatric patients: a single centre retrospective analysis.
Matthes-Martin S, Lamche M, Ladenstein R, Emminger W, Felsberger C, Topf R, Gadner H, Peters C. Matthes-Martin S, et al. Bone Marrow Transplant. 1999 May;23(10):1049-53. doi: 10.1038/sj.bmt.1701754. Bone Marrow Transplant. 1999. PMID: 10373072
One hundred and fifty five pediatric patients underwent allogeneic bone marrow transplantation between 1980 and 1996 in the St Anna Children's Hospital in Vienna with an overall survival of 52.3% (81 patients). Seventy-three patients with a minimum observation time of 1 ye …
One hundred and fifty five pediatric patients underwent allogeneic bone marrow transplantation between 1980 and 1996 in the St Anna Children …