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Quoted phrase not found in phrase index: "Gain of Chromosome 13"
Page 1
Biology and therapy of pediatric rhabdomyosarcoma.
Pappo AS, Shapiro DN, Crist WM, Maurer HM. Pappo AS, et al. J Clin Oncol. 1995 Aug;13(8):2123-39. doi: 10.1200/JCO.1995.13.8.2123. J Clin Oncol. 1995. PMID: 7636557 Review.
Recognition of prognostically important patient groups primarily identified by tumor extent, site, and histology, and development of effective risk-based multimodal therapy in randomized trials, have increased long-term survival in RMS from 25% in 1970 to more than 70% in …
Recognition of prognostically important patient groups primarily identified by tumor extent, site, and histology, and development of effecti …
Cell-free DNA analysis reveals POLR1D-mediated resistance to bevacizumab in colorectal cancer.
Zhou Q, Perakis SO, Ulz P, Mohan S, Riedl JM, Talakic E, Lax S, Tötsch M, Hoefler G, Bauernhofer T, Pichler M, Gerger A, Geigl JB, Heitzer E, Speicher MR. Zhou Q, et al. Genome Med. 2020 Feb 22;12(1):20. doi: 10.1186/s13073-020-0719-6. Genome Med. 2020. PMID: 32087735 Free PMC article.
Using the TCGA data as a comparative and supporting dataset, we defined the minimally amplified overlapping region and studied the mechanistic consequences of copy number gain of the involved genes in this segment. In addition, we established an in vitro cell model and con …
Using the TCGA data as a comparative and supporting dataset, we defined the minimally amplified overlapping region and studied the mechanist …
Sporadic aneuploidy in PHA-stimulated lymphocytes of trisomies 21, 18, and 13.
Reish O, Regev M, Kanesky A, Girafi S, Mashevich M. Reish O, et al. Cytogenet Genome Res. 2011;133(2-4):184-9. doi: 10.1159/000323504. Epub 2011 Jan 19. Cytogenet Genome Res. 2011. PMID: 21252489
Following the observation detected in a previous study that X chromosome monosomy in Turner's syndrome genotypes was associated with a sporadic loss and/or gain of other chromosomes, we studied here whether this instability is a consistent finding in constitutional autosom …
Following the observation detected in a previous study that X chromosome monosomy in Turner's syndrome genotypes was associated with a spora …
An increased frequency of 13q deletions detected by fluorescence in situ hybridization and its impact on survival in children and adolescents with Burkitt lymphoma: results from the Children's Oncology Group study CCG-5961.
Nelson M, Perkins SL, Dave BJ, Coccia PF, Bridge JA, Lyden ER, Heerema NA, Lones MA, Harrison L, Cairo MS, Sanger WG. Nelson M, et al. Br J Haematol. 2010 Feb;148(4):600-10. doi: 10.1111/j.1365-2141.2009.07967.x. Epub 2009 Nov 4. Br J Haematol. 2010. PMID: 19895612 Free PMC article.
Nearly all BLs contain rearrangements of the MYC/8q24 region; however, recent cytogenetic studies suggest that certain secondary chromosomal aberrations in BL correlate with an adverse prognosis. In this multi-centre study, the frequency and impact on clinical outcome of d …
Nearly all BLs contain rearrangements of the MYC/8q24 region; however, recent cytogenetic studies suggest that certain secondary chromosomal …
Different genetic pathways in leukemogenesis for patients presenting with therapy-related myelodysplasia and therapy-related acute myeloid leukemia.
Pedersen-Bjergaard J, Pedersen M, Roulston D, Philip P. Pedersen-Bjergaard J, et al. Blood. 1995 Nov 1;86(9):3542-52. Blood. 1995. PMID: 7579462 Free article.
Loss of a whole chromosome 5 (-5) was also a primary event, but surprisingly, was observed equally in t-MDS and in t-AML. Deletion of chromosome 13, including bands q13q14, was another less common primary aberration of t-MDS. ...These included balanced aberrations i …
Loss of a whole chromosome 5 (-5) was also a primary event, but surprisingly, was observed equally in t-MDS and in t-AML. Deletion of chr …
Abnormalities of chromosome bands 13q12 to 13q14 in childhood acute lymphoblastic leukemia.
Heerema NA, Sather HN, Sensel MG, Lee MK, Hutchinson RJ, Nachman JB, Reaman GH, Lange BJ, Steinherz PG, Bostrom BC, Gaynon PS, Uckun FM. Heerema NA, et al. J Clin Oncol. 2000 Nov 15;18(22):3837-44. doi: 10.1200/JCO.2000.18.22.3837. J Clin Oncol. 2000. PMID: 11078497
Eight cases had balanced rearrangements of 13q12-14, 27 patients had a partial loss of 13q, and one had both a partial gain and a partial loss. The most frequent additional abnormalities among these patients were an abnormal 12p, a del(6q), a del(9p), a 14q11 breakpoint, a …
Eight cases had balanced rearrangements of 13q12-14, 27 patients had a partial loss of 13q, and one had both a partial gain and a par …
Alteration of AKAP220, an upstream component of the Rb pathway, in oral carcinogenesis.
Garnis C, Rosin MP, Zhang L, Lam WL. Garnis C, et al. Int J Cancer. 2005 Sep 20;116(5):813-9. doi: 10.1002/ijc.21065. Int J Cancer. 2005. PMID: 15849745 Free article.
Recurrent gain of a approximately 400 bp signal was observed in multiple patients. This gain was localized to 13q14.11, a region frequently altered in multiple cancer types. ...
Recurrent gain of a approximately 400 bp signal was observed in multiple patients. This gain was localized to 13q14.11, a regi …
Progressive but previously untreated CLL patients with greater array CGH complexity exhibit a less durable response to chemoimmunotherapy.
Kay NE, Eckel-Passow JE, Braggio E, Vanwier S, Shanafelt TD, Van Dyke DL, Jelinek DF, Tschumper RC, Kipps T, Byrd JC, Fonseca R. Kay NE, et al. Cancer Genet Cytogenet. 2010 Dec;203(2):161-8. doi: 10.1016/j.cancergencyto.2010.09.003. Cancer Genet Cytogenet. 2010. PMID: 21156228 Free PMC article.
To better understand the implications of genomic instability and outcome in B-cell chronic lymphocytic leukemia (CLL), we sought to address genomic complexity as a predictor of chemosensitivity and ultimately clinical outcome in this disease. We used array-based comparativ …
To better understand the implications of genomic instability and outcome in B-cell chronic lymphocytic leukemia (CLL), we sought to address …
Multiple myeloma: an update on biology and treatment.
Ludwig H, Meran J, Zojer N. Ludwig H, et al. Ann Oncol. 1999;10 Suppl 6:31-43. Ann Oncol. 1999. PMID: 10676551 Review.
Increasing evidence favours a pre-switched, but somatically mutated B-cell as myeloma stem cell to give rise to the malignant clone. Deletions of the p53-gene, partial or total loss of chromosome 13 and rearrangements of band 14q32 and 11q13 are frequently found in …
Increasing evidence favours a pre-switched, but somatically mutated B-cell as myeloma stem cell to give rise to the malignant clone. Deletio …
Translocation (12;13) in a case of infantile fibrosarcoma.
Strehl S, Ladenstein R, Wrba F, Salzer-Kuntschik M, Gadner H, Ambros PF. Strehl S, et al. Cancer Genet Cytogenet. 1993 Nov;71(1):94-6. doi: 10.1016/0165-4608(93)90207-3. Cancer Genet Cytogenet. 1993. PMID: 8275459
Cytogenetic analysis of an infantile fibrosarcoma showed the presence of a t(12;13) and numerical changes of chromosomes 15 and 20. Until now only non-random gain or loss of total chromosomes as well as one case with a deletion at 17p have been reported for this kin …
Cytogenetic analysis of an infantile fibrosarcoma showed the presence of a t(12;13) and numerical changes of chromosomes 15 and 20. Until no …
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