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Quoted phrase not found in phrase index: "Gain of Chromosome 5p"
Page 1
Clinical characteristics and treatment outcomes of newly diagnosed multiple myeloma with chromosome 1q abnormalities.
Abdallah N, Greipp P, Kapoor P, Gertz MA, Dispenzieri A, Baughn LB, Lacy MQ, Hayman SR, Buadi FK, Dingli D, Go RS, Hwa YL, Fonder A, Hobbs M, Lin Y, Leung N, Kourelis T, Warsame R, Siddiqui M, Lust J, Kyle RA, Bergsagel L, Ketterling R, Rajkumar SV, Kumar SK. Abdallah N, et al. Blood Adv. 2020 Aug 11;4(15):3509-3519. doi: 10.1182/bloodadvances.2020002218. Blood Adv. 2020. PMID: 32750129 Free PMC article.
A gain in chromosome 1q (+1q) is among the most common cytogenetic abnormalities in multiple myeloma (MM). ...We included 1376 Mayo Clinic patients diagnosed with MM from 2005 to 2018 who underwent fluorescence in situ hybridization testing at diagnosis with a panel …
A gain in chromosome 1q (+1q) is among the most common cytogenetic abnormalities in multiple myeloma (MM). ...We included 1376 …
microRNA-99a-5p induces cellular senescence in gemcitabine-resistant bladder cancer by targeting SMARCD1.
Tamai M, Tatarano S, Okamura S, Fukumoto W, Kawakami I, Osako Y, Sakaguchi T, Sugita S, Yonemori M, Yamada Y, Nakagawa M, Enokida H, Yoshino H. Tamai M, et al. Mol Oncol. 2022 Mar;16(6):1329-1346. doi: 10.1002/1878-0261.13192. Epub 2022 Feb 28. Mol Oncol. 2022. PMID: 35148461 Free PMC article.
In gain-of-function studies, miR-99a-5p inhibited cell viabilities and restored sensitivity to gemcitabine. RNA sequencing analysis was performed to find the target gene of miR-99a-5p. SMARCD1 was selected as a candidate gene. Dual-luciferase reporter assays …
In gain-of-function studies, miR-99a-5p inhibited cell viabilities and restored sensitivity to gemcitabine. RNA sequencing ana …
Genomic and transcriptomic characterization of desmoplastic small round cell tumors.
Sydow S, Versleijen-Jonkers YMH, Hansson M, van Erp AEM, Hillebrandt-Roeffen MHS, van der Graaf WTA, Piccinelli P, Rissler P, Flucke UE, Mertens F. Sydow S, et al. Genes Chromosomes Cancer. 2021 Sep;60(9):595-603. doi: 10.1002/gcc.22955. Epub 2021 May 17. Genes Chromosomes Cancer. 2021. PMID: 33928700
We here studied 25 samples from 19 DSRCT patients using single nucleotide polymorphism arrays and found that all samples had copy number alterations. The most common imbalances were gain of chromosomes/chromosome arms 1/1q and 5/5p and loss of 6/6q and …
We here studied 25 samples from 19 DSRCT patients using single nucleotide polymorphism arrays and found that all samples had copy number alt …
The Importance of FISH Signal Cut-off Value and Copy Number Variation for 1q21 in Newly Diagnosed Multiple Myeloma: Is it Underestimated?
Gao L, Liu Y, Li Y, Feng L, Wang Z, Wen L, Wang F, Huang X, Lu J, Lai Y. Gao L, et al. Clin Lymphoma Myeloma Leuk. 2022 Jul;22(7):535-544. doi: 10.1016/j.clml.2022.01.013. Epub 2022 Jan 31. Clin Lymphoma Myeloma Leuk. 2022. PMID: 35292207
BACKGROUND: The cut-off value for gain/amplification of 1q21(1q21+) was 20% according to the recommendations of the European Myeloma Network and there were limited studies concerning less than 20%. ...
BACKGROUND: The cut-off value for gain/amplification of 1q21(1q21+) was 20% according to the recommendations of the European Myeloma …
Mutations in osteoprotegerin account for the CCAL1 locus in calcium pyrophosphate deposition disease.
Williams CJ, Qazi U, Bernstein M, Charniak A, Gohr C, Mitton-Fitzgerald E, Ortiz A, Cardinal L, Kaell AT, Rosenthal AK. Williams CJ, et al. Osteoarthritis Cartilage. 2018 Jun;26(6):797-806. doi: 10.1016/j.joca.2018.03.005. Epub 2018 Mar 22. Osteoarthritis Cartilage. 2018. PMID: 29578045 Free PMC article.
OBJECTIVE: Mutations on chromosomes 5p (CCAL2) and 8q (CCAL1) have been linked to familial forms of calcium pyrophosphate deposition disease (CPDD). ...Recently, a single Dutch kindred with a mutation in the Tumor Necrosis Factor Receptor Super Family member 11B (TN …
OBJECTIVE: Mutations on chromosomes 5p (CCAL2) and 8q (CCAL1) have been linked to familial forms of calcium pyrophosphate depo …
Integrative analysis of microRNA, mRNA and aCGH data reveals asbestos- and histology-related changes in lung cancer.
Nymark P, Guled M, Borze I, Faisal A, Lahti L, Salmenkivi K, Kettunen E, Anttila S, Knuutila S. Nymark P, et al. Genes Chromosomes Cancer. 2011 Aug;50(8):585-97. doi: 10.1002/gcc.20880. Epub 2011 May 11. Genes Chromosomes Cancer. 2011. PMID: 21563230
Both known and new lung cancer-associated miRNAs and target genes with inverse correlation were discovered. Furthermore, DNA copy number alterations (e.g., gain at 12p13.31) were correlated with the deregulated miRNAs. Specifically, thirteen novel asbestos-related miRNAs ( …
Both known and new lung cancer-associated miRNAs and target genes with inverse correlation were discovered. Furthermore, DNA copy number alt …
Inflammatory leiomyosarcoma/rhabdomyoblastic tumor: A report of two cases with novel genetic findings.
Sukhanova M, Obeidin F, Streich L, Alexiev BA. Sukhanova M, et al. Genes Chromosomes Cancer. 2022 Nov;61(11):653-661. doi: 10.1002/gcc.23072. Epub 2022 Jun 30. Genes Chromosomes Cancer. 2022. PMID: 35655404 Free PMC article.
The tumors were composed of sheets and fascicles of variably pleomorphic tumor cells showing spindled and epithelioid to rhabdoid morphology and a prominent histiocyte-rich inflammatory infiltrate typical of ILMS/IRT. In case 1, chromosomal microarray analysis showed a nea …
The tumors were composed of sheets and fascicles of variably pleomorphic tumor cells showing spindled and epithelioid to rhabdoid morphology …
A recurrent gain of chromosome arm 3q in primary squamous carcinoma of the vagina.
Habermann JK, Hellman K, Freitag S, Heselmeyer-Haddad K, Hellström AC, Shah K, Auer G, Ried T. Habermann JK, et al. Cancer Genet Cytogenet. 2004 Jan 1;148(1):7-13. doi: 10.1016/s0165-4608(03)00245-0. Cancer Genet Cytogenet. 2004. PMID: 14697635
Analysis of 16 formalin-fixed and paraffin-embedded tumors revealed that 70% of vaginal carcinomas carry relative copy number increases that map to chromosome arm 3q. Other recurring gains were observed on chromosome arms 5p and 19p. Chromosomal losses …
Analysis of 16 formalin-fixed and paraffin-embedded tumors revealed that 70% of vaginal carcinomas carry relative copy number increases that …
Oncogenetic tree modeling of human hepatocarcinogenesis.
Longerich T, Mueller MM, Breuhahn K, Schirmacher P, Benner A, Heiss C. Longerich T, et al. Int J Cancer. 2012 Feb 1;130(3):575-83. doi: 10.1002/ijc.26063. Epub 2011 May 9. Int J Cancer. 2012. PMID: 21400513 Free article.
Whereas gains of 1q and 8q together with losses of 8p formed a cluster that represents early etiology-independent alterations, the associations of gains at 6q and 17q as well as losses of 6p and 9p were observed during tumor progression. HBV-induced HCCs had significantly more …
Whereas gains of 1q and 8q together with losses of 8p formed a cluster that represents early etiology-independent alterations, the associati …
Genomic profiling of advanced-stage oral cancers reveals chromosome 11q alterations as markers of poor clinical outcome.
Ambatipudi S, Gerstung M, Gowda R, Pai P, Borges AM, Schäffer AA, Beerenwinkel N, Mahimkar MB. Ambatipudi S, et al. PLoS One. 2011 Feb 28;6(2):e17250. doi: 10.1371/journal.pone.0017250. PLoS One. 2011. PMID: 21386901 Free PMC article.
The specific genomic alterations so identified were evaluated for their potential clinical relevance. Copy-number changes were observed on chromosomal arms with most frequent gains on 3q (60%), 5p (50%), 7p (50%), 8q (73%), 11q13 (47%), 14q11.2 (47%), and 19p13.3 (5 …
The specific genomic alterations so identified were evaluated for their potential clinical relevance. Copy-number changes were observed on …
45 results