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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
2004 1
2006 2
2008 2
2010 3
2011 7
2012 13
2013 35
2014 96
2015 243
2016 366
2017 469
2018 489
2019 504
2020 597
2021 747
2022 740
2023 623
2024 215

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4,417 results

Results by year

Filters applied: Meta-Analysis, Review, Systematic Review, in the last 10 years. Clear all
Page 1
CRISPR/Cas Genome Editing and Precision Plant Breeding in Agriculture.
Chen K, Wang Y, Zhang R, Zhang H, Gao C. Chen K, et al. Annu Rev Plant Biol. 2019 Apr 29;70:667-697. doi: 10.1146/annurev-arplant-050718-100049. Epub 2019 Mar 5. Annu Rev Plant Biol. 2019. PMID: 30835493 Review.
Here, we review advances in CRISPR/Cas9 and its variants and examine their applications in plant genome editing and related manipulations. We highlight base-editing tools that enable targeted nucleotide substitutions and describe the various delivery systems, partic …
Here, we review advances in CRISPR/Cas9 and its variants and examine their applications in plant genome editing and related ma …
Genome Editing: Past, Present, and Future.
Carroll D. Carroll D. Yale J Biol Med. 2017 Dec 19;90(4):653-659. eCollection 2017 Dec. Yale J Biol Med. 2017. PMID: 29259529 Free PMC article. Review.
The CRISPR-Cas genome editing tools have been adopted rapidly in the research community, and they are quickly finding applications in the commercial sector as well. Lest we lose track of the broader context, this Perspective presents a brief review of the history of …
The CRISPR-Cas genome editing tools have been adopted rapidly in the research community, and they are quickly finding applicat …
The genome editing revolution.
van der Oost J, Patinios C. van der Oost J, et al. Trends Biotechnol. 2023 Mar;41(3):396-409. doi: 10.1016/j.tibtech.2022.12.022. Epub 2023 Jan 27. Trends Biotechnol. 2023. PMID: 36709094 Free article. Review.
A series of spectacular scientific discoveries and technological advances in the second half of the 20th century have provided the basis for the ongoing genome editing revolution. The elucidation of structural and functional features of DNA and RNA was followed by p …
A series of spectacular scientific discoveries and technological advances in the second half of the 20th century have provided the basis for …
CRISPR/Cas9-Based Genome Editing in Plants.
Zhang Y, Ma X, Xie X, Liu YG. Zhang Y, et al. Prog Mol Biol Transl Sci. 2017;149:133-150. doi: 10.1016/bs.pmbts.2017.03.008. Epub 2017 May 12. Prog Mol Biol Transl Sci. 2017. PMID: 28712494 Review.
Recently, genome editing technologies have shown great potential in plants. ...Indeed, due to its advantages of simplicity and high efficiency, the CRISPR/Cas9-based genome editing system is becoming a powerful tool in plant science research. ...
Recently, genome editing technologies have shown great potential in plants. ...Indeed, due to its advantages of simplicity and …
Genome Editing among Bioethics and Regulatory Practices.
Mandrioli M. Mandrioli M. Biomolecules. 2021 Dec 22;12(1):13. doi: 10.3390/biom12010013. Biomolecules. 2021. PMID: 35053161 Free PMC article. Review.
In the last decade, genome editing technologies became very effective and several clinical trials have been started in order to use them for treating some genetic diseases. Interestingly, despite more than 50 years of discussion about the frontiers of genetics in hu …
In the last decade, genome editing technologies became very effective and several clinical trials have been started in order t …
Human Genome Editing: Science, Ethics, and Governance.
National Academies of Sciences, Engineering, and Medicine; National Academy of Medicine; National Academy of Sciences; Committee on Human Gene Editing: Scientific, Medical, and Ethical Considerations. National Academies of Sciences, Engineering, and Medicine, et al. Washington (DC): National Academies Press (US); 2017 Feb 14. Washington (DC): National Academies Press (US); 2017 Feb 14. PMID: 28796468 Free Books & Documents. Review.
Genome editing is a powerful new tool for making precise alterations to an organism's genetic material. Recent scientific advances have made genome editing more efficient, precise, and flexible than ever before. ...
Genome editing is a powerful new tool for making precise alterations to an organism's genetic material. Recent scientific adva …
Ethics of Human Genome Editing.
Coller BS. Coller BS. Annu Rev Med. 2019 Jan 27;70:289-305. doi: 10.1146/annurev-med-112717-094629. Annu Rev Med. 2019. PMID: 30691366 Review.
Crossing the so-called red line of germline genome editing raises important bioethical issues, most importantly, serious concern about the potential negative impact on individuals with disabilities. This review highlights some of the major ethical considerations in …
Crossing the so-called red line of germline genome editing raises important bioethical issues, most importantly, serious conce …
The genome editing revolution: review.
Khalil AM. Khalil AM. J Genet Eng Biotechnol. 2020 Oct 29;18(1):68. doi: 10.1186/s43141-020-00078-y. J Genet Eng Biotechnol. 2020. PMID: 33123803 Free PMC article. Review.
Introducing constructs into target cells or organisms is the key step in genome engineering. CONCLUSIONS: Despite the success already achieved, the genome editing techniques are still suffering certain difficulties. Challenges must be overcome before the full potent …
Introducing constructs into target cells or organisms is the key step in genome engineering. CONCLUSIONS: Despite the success already achiev …
CRISPR-Cas for genome editing: Classification, mechanism, designing and applications.
Bhatia S, Pooja, Yadav SK. Bhatia S, et al. Int J Biol Macromol. 2023 May 31;238:124054. doi: 10.1016/j.ijbiomac.2023.124054. Epub 2023 Mar 17. Int J Biol Macromol. 2023. PMID: 36933595 Review.
The characteristic of the CRISPR-Cas9 system to target DNA sequences using programmable RNAs has opened new arenas due to which today CRISPR-Cas has evolved as cutting end technique in the field of genome editing. Here, we discuss about the evolution of CRISPR, its …
The characteristic of the CRISPR-Cas9 system to target DNA sequences using programmable RNAs has opened new arenas due to which today CRISPR …
Genome Editing and Cardiac Arrhythmias.
Moore OM, Ho KS, Copeland JS, Parthasarathy V, Wehrens XHT. Moore OM, et al. Cells. 2023 May 11;12(10):1363. doi: 10.3390/cells12101363. Cells. 2023. PMID: 37408197 Free PMC article. Review.
First, we discuss genome editing methods by which DNA can be disrupted, inserted, deleted, or corrected in cardiomyocytes. Second, we provide an overview of in vivo genome editing in preclinical models of heritable and acquired arrhythmias. ...
First, we discuss genome editing methods by which DNA can be disrupted, inserted, deleted, or corrected in cardiomyocytes. Sec …
4,417 results