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Year Number of Results
1985 1
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1996 5
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1998 8
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2002 10
2003 10
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2007 10
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626 results

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Quoted phrase not found in phrase index: "Glioma susceptibility 1"
Page 1
Altered cellular metabolism in gliomas - an emerging landscape of actionable co-dependency targets.
Bi J, Chowdhry S, Wu S, Zhang W, Masui K, Mischel PS. Bi J, et al. Nat Rev Cancer. 2020 Jan;20(1):57-70. doi: 10.1038/s41568-019-0226-5. Epub 2019 Dec 5. Nat Rev Cancer. 2020. PMID: 31806884 Review.
Altered cellular metabolism is a hallmark of gliomas. Propelled by a set of recent technological advances, new insights into the molecular mechanisms underlying glioma metabolism are rapidly emerging. ...Finally, a road map for the discovery of potential new glio …
Altered cellular metabolism is a hallmark of gliomas. Propelled by a set of recent technological advances, new insights into the mole …
An update on the central nervous system manifestations of neurofibromatosis type 1.
Nix JS, Blakeley J, Rodriguez FJ. Nix JS, et al. Acta Neuropathol. 2020 Apr;139(4):625-641. doi: 10.1007/s00401-019-02002-2. Epub 2019 Apr 8. Acta Neuropathol. 2020. PMID: 30963251 Free PMC article. Review.
Neurofibromatosis 1 (NF1) is an autosomal dominant genetic disorder that presents with variable phenotypes as a result of mutations in the neurofibromatosis type 1 (NF1) gene and subsequently, abnormal function of the protein product, neurofibromin. ...In addition, …
Neurofibromatosis 1 (NF1) is an autosomal dominant genetic disorder that presents with variable phenotypes as a result of mutations i …
2-Hydroxyglutarate in Cancer Cells.
Ježek P. Ježek P. Antioxid Redox Signal. 2020 Nov 1;33(13):903-926. doi: 10.1089/ars.2019.7902. Epub 2020 Jan 22. Antioxid Redox Signal. 2020. PMID: 31847543 Free PMC article. Review.
Critical Issues: Typically, heterozygous mutations within the active sites of isocitrate dehydrogenase isoform 1 (IDH1)(R132H) and mitochondrial isocitrate dehydrogenase isoform 2 (IDH2)(R140Q) provide cells with millimolar r-2-hydroxyglutarate (r-2HG) concentrations, wher …
Critical Issues: Typically, heterozygous mutations within the active sites of isocitrate dehydrogenase isoform 1 (IDH1)(R132H) and mi …
Tumor antigens in glioma.
Nejo T, Yamamichi A, Almeida ND, Goretsky YE, Okada H. Nejo T, et al. Semin Immunol. 2020 Feb;47:101385. doi: 10.1016/j.smim.2020.101385. Epub 2020 Feb 6. Semin Immunol. 2020. PMID: 32037183 Review.
Still, the paucity of effective antigen targets remains a significant obstacle in safely and effectively treating glioblastoma and other malignant gliomas with relatively low mutation loads. In this review, we highlight the current understanding of and development of immun …
Still, the paucity of effective antigen targets remains a significant obstacle in safely and effectively treating glioblastoma and other mal …
Gliomas in Children.
Filbin MG, Sturm D. Filbin MG, et al. Semin Neurol. 2018 Feb;38(1):121-130. doi: 10.1055/s-0038-1635106. Epub 2018 Mar 16. Semin Neurol. 2018. PMID: 29548059 Review.
Although the exact cells of origin for most pediatric gliomas remain to be identified, our current understanding is that specific cell populations during CNS development are susceptible to particular oncogenic events during certain time windows and thus give rise to …
Although the exact cells of origin for most pediatric gliomas remain to be identified, our current understanding is that specific cel …
MR Perfusion Imaging for Gliomas.
Lee J, Chen MM, Liu HL, Ucisik FE, Wintermark M, Kumar VA. Lee J, et al. Magn Reson Imaging Clin N Am. 2024 Feb;32(1):73-83. doi: 10.1016/j.mric.2023.07.003. Epub 2023 Aug 22. Magn Reson Imaging Clin N Am. 2024. PMID: 38007284 Review.
Accurate diagnosis and treatment evaluation of patients with gliomas is imperative to make clinical decisions. Multiparametric MR perfusion imaging reveals physiologic features of gliomas that can help classify them according to their histologic and molecular featur …
Accurate diagnosis and treatment evaluation of patients with gliomas is imperative to make clinical decisions. Multiparametric MR per …
Spectrum and prevalence of genetic predisposition in medulloblastoma: a retrospective genetic study and prospective validation in a clinical trial cohort.
Waszak SM, Northcott PA, Buchhalter I, Robinson GW, Sutter C, Groebner S, Grund KB, Brugières L, Jones DTW, Pajtler KW, Morrissy AS, Kool M, Sturm D, Chavez L, Ernst A, Brabetz S, Hain M, Zichner T, Segura-Wang M, Weischenfeldt J, Rausch T, Mardin BR, Zhou X, Baciu C, Lawerenz C, Chan JA, Varlet P, Guerrini-Rousseau L, Fults DW, Grajkowska W, Hauser P, Jabado N, Ra YS, Zitterbart K, Shringarpure SS, De La Vega FM, Bustamante CD, Ng HK, Perry A, MacDonald TJ, Hernáiz Driever P, Bendel AE, Bowers DC, McCowage G, Chintagumpala MM, Cohn R, Hassall T, Fleischhack G, Eggen T, Wesenberg F, Feychting M, Lannering B, Schüz J, Johansen C, Andersen TV, Röösli M, Kuehni CE, Grotzer M, Kjaerheim K, Monoranu CM, Archer TC, Duke E, Pomeroy SL, Shelagh R, Frank S, Sumerauer D, Scheurlen W, Ryzhova MV, Milde T, Kratz CP, Samuel D, Zhang J, Solomon DA, Marra M, Eils R, Bartram CR, von Hoff K, Rutkowski S, Ramaswamy V, Gilbertson RJ, Korshunov A, Taylor MD, Lichter P, Malkin D, Gajjar A, Korbel JO, Pfister SM. Waszak SM, et al. Lancet Oncol. 2018 Jun;19(6):785-798. doi: 10.1016/S1470-2045(18)30242-0. Epub 2018 May 9. Lancet Oncol. 2018. PMID: 29753700 Free PMC article.
Previously defined somatic mutational signatures were used to further classify medulloblastoma genomes into two groups, a clock-like group (signatures 1 and 5) and a homologous recombination repair deficiency-like group (signatures 3 and 8), and chromothripsis was investig …
Previously defined somatic mutational signatures were used to further classify medulloblastoma genomes into two groups, a clock-like group ( …
Role of PVT1 polymorphisms in the glioma susceptibility and prognosis.
Ding X, Zhao Y, Yuan H, Zhang Y, Gao Y. Ding X, et al. Eur J Cancer Prev. 2021 Sep 1;30(5):400-408. doi: 10.1097/CEJ.0000000000000636. Eur J Cancer Prev. 2021. PMID: 33443959
BACKGROUND: Genetic factors play a crucial role in the glioma risk and prognosis of glioma patients. To explore the role of plasmacytoma variant translocation 1 (PVT1) polymorphism in the susceptibility and survival of glioma in the Chinese Han …
BACKGROUND: Genetic factors play a crucial role in the glioma risk and prognosis of glioma patients. To explore the role of pl …
XPG gene polymorphisms and glioma susceptibility: a two-centre case-control study.
Yuan L, Hu WM, Chen K, Shi Q, Lin A, Chen HT, Zhuo ZJ, Zeng L. Yuan L, et al. Br J Biomed Sci. 2021 Jul;78(3):135-140. doi: 10.1080/09674845.2020.1870308. Epub 2021 Feb 5. Br J Biomed Sci. 2021. PMID: 33393424
Xeroderma pigmentosum group G (XPG) plays a key role in the nucleotide excision repair pathway, which may modulate individual susceptibility to developing cancer. We hypothesized links between XPG variants and glioma in children.Methods: We tested our hypothesis in …
Xeroderma pigmentosum group G (XPG) plays a key role in the nucleotide excision repair pathway, which may modulate individual susceptibil …
Inherited predisposition to glioma.
Kyritsis AP, Bondy ML, Rao JS, Sioka C. Kyritsis AP, et al. Neuro Oncol. 2010 Jan;12(1):104-13. doi: 10.1093/neuonc/nop011. Epub 2009 Nov 23. Neuro Oncol. 2010. PMID: 20150373 Free PMC article. Review.
In gliomas, germline gene alterations play a significant role during malignant transformation of progenitor glial cells, at least for families with occurrence of multiple cancers or with specific hereditary cancer syndromes. ...Future molecular diagnosis may identify new g …
In gliomas, germline gene alterations play a significant role during malignant transformation of progenitor glial cells, at least for …
626 results