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Year Number of Results
1978 1
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1989 1
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1993 3
1994 2
1995 1
1996 3
1997 3
1998 1
1999 1
2000 2
2001 6
2002 5
2003 3
2004 6
2005 9
2006 14
2007 8
2008 17
2009 13
2010 16
2011 19
2012 18
2013 28
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385 results

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Quoted phrase not found in phrase index: "Glioma susceptibility 3"
Page 1
Association Between Telomere Length and Risk of Cancer and Non-Neoplastic Diseases: A Mendelian Randomization Study.
Telomeres Mendelian Randomization Collaboration; Haycock PC, Burgess S, Nounu A, Zheng J, Okoli GN, Bowden J, Wade KH, Timpson NJ, Evans DM, Willeit P, Aviv A, Gaunt TR, Hemani G, Mangino M, Ellis HP, Kurian KM, Pooley KA, Eeles RA, Lee JE, Fang S, Chen WV, Law MH, Bowdler LM, Iles MM, Yang Q, Worrall BB, Markus HS, Hung RJ, Amos CI, Spurdle AB, Thompson DJ, O'Mara TA, Wolpin B, Amundadottir L, Stolzenberg-Solomon R, Trichopoulou A, Onland-Moret NC, Lund E, Duell EJ, Canzian F, Severi G, Overvad K, Gunter MJ, Tumino R, Svenson U, van Rij A, Baas AF, Bown MJ, Samani NJ, van t'Hof FNG, Tromp G, Jones GT, Kuivaniemi H, Elmore JR, Johansson M, Mckay J, Scelo G, Carreras-Torres R, Gaborieau V, Brennan P, Bracci PM, Neale RE, Olson SH, Gallinger S, Li D, Petersen GM, Risch HA, Klein AP, Han J, Abnet CC, Freedman ND, Taylor PR, Maris JM, Aben KK, Kiemeney LA, Vermeulen SH, Wiencke JK, Walsh KM, Wrensch M, Rice T, Turnbull C, Litchfield K, Paternoster L, Standl M, Abecasis GR, SanGiovanni JP, Li Y, Mijatovic V, Sapkota Y, Low SK, Zondervan KT, Montgomery GW, Nyholt DR, van Heel DA, Hunt K, Arking DE, Ashar FN, Sotoodehnia N, Woo D, Rosand J, Comeau ME, Brown WM, Silverman EK, Hokanson JE,… See abstract for full author list ➔ Telomeres Mendelian Randomization Collaboration, et al. JAMA Oncol. 2017 May 1;3(5):636-651. doi: 10.1001/jamaoncol.2016.5945. JAMA Oncol. 2017. PMID: 28241208 Free PMC article.
IMPORTANCE: The causal direction and magnitude of the association between telomere length and incidence of cancer and non-neoplastic diseases is uncertain owing to the susceptibility of observational studies to confounding and reverse causation. ...The strongest ass …
IMPORTANCE: The causal direction and magnitude of the association between telomere length and incidence of cancer and non-neoplastic disease …
Comparison of Cancer Prevalence in Patients With Neurofibromatosis Type 1 at an Academic Cancer Center vs in the General Population From 1985 to 2020.
Landry JP, Schertz KL, Chiang YJ, Bhalla AD, Yi M, Keung EZ, Scally CP, Feig BW, Hunt KK, Roland CL, Guadagnolo A, Bishop AJ, Lazar AJ, Slopis JM, McCutcheon IE, Torres KE. Landry JP, et al. JAMA Netw Open. 2021 Mar 1;4(3):e210945. doi: 10.1001/jamanetworkopen.2021.0945. JAMA Netw Open. 2021. PMID: 33734413 Free PMC article.
Survival curves were compared using the log-rank test. Deaths from disease were considered a DSS end point; other deaths were considered censored observations. ...RESULTS: Among 1607 patients with NF1, the median (range) age at initial visit was 19 years (1 month to …
Survival curves were compared using the log-rank test. Deaths from disease were considered a DSS end point; other deaths were conside …
Spectrum and prevalence of genetic predisposition in medulloblastoma: a retrospective genetic study and prospective validation in a clinical trial cohort.
Waszak SM, Northcott PA, Buchhalter I, Robinson GW, Sutter C, Groebner S, Grund KB, Brugières L, Jones DTW, Pajtler KW, Morrissy AS, Kool M, Sturm D, Chavez L, Ernst A, Brabetz S, Hain M, Zichner T, Segura-Wang M, Weischenfeldt J, Rausch T, Mardin BR, Zhou X, Baciu C, Lawerenz C, Chan JA, Varlet P, Guerrini-Rousseau L, Fults DW, Grajkowska W, Hauser P, Jabado N, Ra YS, Zitterbart K, Shringarpure SS, De La Vega FM, Bustamante CD, Ng HK, Perry A, MacDonald TJ, Hernáiz Driever P, Bendel AE, Bowers DC, McCowage G, Chintagumpala MM, Cohn R, Hassall T, Fleischhack G, Eggen T, Wesenberg F, Feychting M, Lannering B, Schüz J, Johansen C, Andersen TV, Röösli M, Kuehni CE, Grotzer M, Kjaerheim K, Monoranu CM, Archer TC, Duke E, Pomeroy SL, Shelagh R, Frank S, Sumerauer D, Scheurlen W, Ryzhova MV, Milde T, Kratz CP, Samuel D, Zhang J, Solomon DA, Marra M, Eils R, Bartram CR, von Hoff K, Rutkowski S, Ramaswamy V, Gilbertson RJ, Korshunov A, Taylor MD, Lichter P, Malkin D, Gajjar A, Korbel JO, Pfister SM. Waszak SM, et al. Lancet Oncol. 2018 Jun;19(6):785-798. doi: 10.1016/S1470-2045(18)30242-0. Epub 2018 May 9. Lancet Oncol. 2018. PMID: 29753700 Free PMC article.
DNA methylation profiling was done to determine consensus molecular subgroups: WNT (MB(WNT)), SHH (MB(SHH)), group 3 (MB(Group3)), and group 4 (MB(Group4)). Medulloblastoma predisposition genes were predicted on the basis of rare variant burden tests against control …
DNA methylation profiling was done to determine consensus molecular subgroups: WNT (MB(WNT)), SHH (MB(SHH)), group 3 (MB(Group3)), an …
Tumor antigens in glioma.
Nejo T, Yamamichi A, Almeida ND, Goretsky YE, Okada H. Nejo T, et al. Semin Immunol. 2020 Feb;47:101385. doi: 10.1016/j.smim.2020.101385. Epub 2020 Feb 6. Semin Immunol. 2020. PMID: 32037183 Review.
Still, the paucity of effective antigen targets remains a significant obstacle in safely and effectively treating glioblastoma and other malignant gliomas with relatively low mutation loads. In this review, we highlight the current understanding of and development of immun …
Still, the paucity of effective antigen targets remains a significant obstacle in safely and effectively treating glioblastoma and other mal …
Biomarkers for glioma immunotherapy: the next generation.
Sims JS, Ung TH, Neira JA, Canoll P, Bruce JN. Sims JS, et al. J Neurooncol. 2015 Jul;123(3):359-72. doi: 10.1007/s11060-015-1746-9. Epub 2015 Feb 28. J Neurooncol. 2015. PMID: 25724916 Free PMC article. Review.
Molecular indicators have been applied to several aspects of cancer therapy: to describe the genotypic and phenotypic state of neoplastic tissue for prognosis, to predict susceptibility to anti-proliferative agents, to validate the presence of specific drug targets, …
Molecular indicators have been applied to several aspects of cancer therapy: to describe the genotypic and phenotypic state of neoplastic ti …
Epidemiological characteristics and genetic alterations in adult diffuse glioma in East Asian populations.
Mo Z, Xin J, Chai R, Woo PYM, Chan DTM, Wang J. Mo Z, et al. Cancer Biol Med. 2022 Nov 1;19(10):1440-59. doi: 10.20892/j.issn.2095-3941.2022.0418. Cancer Biol Med. 2022. PMID: 36350002 Free PMC article. Review.
Multiple genome-wide association studies of various cohorts have revealed single nucleotide polymorphisms associated with overall and subtype-specific glioma susceptibility. Notably, only 3 risk loci-5p15.33, 11q23.3, and 20q13.33-were shared between p …
Multiple genome-wide association studies of various cohorts have revealed single nucleotide polymorphisms associated with overall and subtyp …
Histone H3.3 G34-mutant Diffuse Gliomas in Adults.
Wang L, Shao L, Li H, Yao K, Duan Z, Zhi C, Song S, Cheng Y, Wang F, Wang W, Piao Y, Gui Q, Lu D, Qi X, Teng L. Wang L, et al. Am J Surg Pathol. 2022 Feb 1;46(2):249-257. doi: 10.1097/PAS.0000000000001781. Am J Surg Pathol. 2022. PMID: 34352809
The characteristics of H3.3 G34-mutant gliomas in adults have yet to be specifically described. ...The age at diagnosis of H3.3 G34-mutant diffuse gliomas was significantly younger than IDH/H3 wild-type gliomas (24 vs. 57 y, P<0.001). ...
The characteristics of H3.3 G34-mutant gliomas in adults have yet to be specifically described. ...The age at diagnosis of H3. …
Advances in molecular and imaging biomarkers in lower-grade gliomas.
Picca A, Bruno F, Nichelli L, Sanson M, Rudà R. Picca A, et al. Expert Rev Neurother. 2023 Jul-Dec;23(12):1217-1231. doi: 10.1080/14737175.2023.2285472. Epub 2023 Dec 15. Expert Rev Neurother. 2023. PMID: 37982735 Review.
INTRODUCTION: Lower-grade (grade 2-3) gliomas (LGGs) constitutes a group of primary brain tumors with variable clinical behaviors and treatment responses. ...While the IDH mutation is an established key prognostic and predictive marker, recent results from ID …
INTRODUCTION: Lower-grade (grade 2-3) gliomas (LGGs) constitutes a group of primary brain tumors with variable clinical behavi …
Testing for causality between systematically identified risk factors and glioma: a Mendelian randomization study.
Howell AE, Robinson JW, Wootton RE, McAleenan A, Tsavachidis S, Ostrom QT, Bondy M, Armstrong G, Relton C, Haycock P, Martin RM, Zheng J, Kurian KM. Howell AE, et al. BMC Cancer. 2020 Jun 3;20(1):508. doi: 10.1186/s12885-020-06967-2. BMC Cancer. 2020. PMID: 32493226 Free PMC article.
RESULTS: Our systematic search identified 36 risk factors that could be proxied using genetic variants. Using MR, we found evidence that four genetically predicted traits increased risk of glioma, glioblastoma or non-glioblastoma: longer leukocyte telomere length, l …
RESULTS: Our systematic search identified 36 risk factors that could be proxied using genetic variants. Using MR, we found evidence that fou …
Dynamic susceptibility contrast and diffusion-weighted MRI in posterior fossa pilocytic astrocytoma and medulloblastoma.
Kurokawa R, Umemura Y, Capizzano A, Kurokawa M, Baba A, Holmes A, Kim J, Ota Y, Srinivasan A, Moritani T. Kurokawa R, et al. J Neuroimaging. 2022 May;32(3):511-520. doi: 10.1111/jon.12962. Epub 2022 Jan 7. J Neuroimaging. 2022. PMID: 34997668
This study aimed to evaluate the diagnostic and prognostic performance of dynamic susceptibility contrast (DSC)-MRI parameters and apparent diffusion coefficient (ADC) values between PA and MB. ...All parameters exhibited good diagnostic ability (accuracy >0.80) with nA …
This study aimed to evaluate the diagnostic and prognostic performance of dynamic susceptibility contrast (DSC)-MRI parameters and ap …
385 results