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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1988 1
1990 2
1992 1
1993 2
1996 4
1997 1
1998 2
1999 1
2000 1
2001 3
2002 3
2003 1
2005 2
2006 2
2007 1
2008 1
2009 1
2010 2
2011 5
2012 6
2014 3
2015 3
2016 4
2017 4
2018 4
2019 2
2020 4
2021 3
2022 3
2023 4
2024 3

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73 results

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Page 1
Diabetic Kidney Disease: Challenges, Progress, and Possibilities.
Alicic RZ, Rooney MT, Tuttle KR. Alicic RZ, et al. Clin J Am Soc Nephrol. 2017 Dec 7;12(12):2032-2045. doi: 10.2215/CJN.11491116. Epub 2017 May 18. Clin J Am Soc Nephrol. 2017. PMID: 28522654 Free PMC article.
The natural history of diabetic kidney disease includes glomerular hyperfiltration, progressive albuminuria, declining GFR, and ultimately, ESRD. Metabolic changes associated with diabetes lead to glomerular hypertrophy, glomerulosclerosis, and tubulointerstitial in …
The natural history of diabetic kidney disease includes glomerular hyperfiltration, progressive albuminuria, declining GFR, and ultimately, …
Adiponectin for the treatment of diabetic nephropathy.
Lee JY, Yang JW, Han BG, Choi SO, Kim JS. Lee JY, et al. Korean J Intern Med. 2019 May;34(3):480-491. doi: 10.3904/kjim.2019.109. Epub 2019 Apr 30. Korean J Intern Med. 2019. PMID: 31048658 Free PMC article. Review.
Thus, prevention of glomerular hypertrophy and attenuation of glomerular hyperfiltration may have therapeutic potential for diabetic nephropathy (DN). ...Moreover, the recently developed adiponectin receptor agonist, AdipoRon, shows therapeutic potential for DN. In …
Thus, prevention of glomerular hypertrophy and attenuation of glomerular hyperfiltration may have therapeutic potential for di …
mTOR Inhibition and Kidney Diseases.
Ma MKM, Yung S, Chan TM. Ma MKM, et al. Transplantation. 2018 Feb;102(2S Suppl 1):S32-S40. doi: 10.1097/TP.0000000000001729. Transplantation. 2018. PMID: 29369972 Review.
There are data from basic or animal studies to suggest that sirolimus and its analogs may also benefit patients with autosomal dominant polycystic kidney disease and metabolic- or immune-mediated renal diseases through its ability to reduce glomerular hypertrophy, r …
There are data from basic or animal studies to suggest that sirolimus and its analogs may also benefit patients with autosomal dominant poly …
Nonsteroidal mineralocorticoid antagonists in diabetic kidney disease.
Dojki FK, Bakris G. Dojki FK, et al. Curr Opin Nephrol Hypertens. 2017 Sep;26(5):368-374. doi: 10.1097/MNH.0000000000000340. Curr Opin Nephrol Hypertens. 2017. PMID: 28771453 Review.
PURPOSE OF REVIEW: Current data highlight the pathological aspects of excess aldosterone in promoting glomerular hypertrophy, glomerulosclerosis, and proteinuria in diabetic kidney disease (DKD). The role of nonsteroidal mineralocorticoid receptor antagonists (MRAs) …
PURPOSE OF REVIEW: Current data highlight the pathological aspects of excess aldosterone in promoting glomerular hypertrophy, …
Uric acid--a uremic toxin?
Nakagawa T, Mazzali M, Kang DH, Sánchez-Lozada LG, Herrera-Acosta J, Johnson RJ. Nakagawa T, et al. Blood Purif. 2006;24(1):67-70. doi: 10.1159/000089440. Blood Purif. 2006. PMID: 16361844 Free article. Review.
To generate mild hyperuricemia without intrarenal crystal in rats, we used low doses of an uricase inhibitor (2% oxonic acid). Hyperuricemia induced systemic hypertension, glomerular hypertrophy/hypertension, afferent arteriolar sclerosis, and macrophage infiltratio …
To generate mild hyperuricemia without intrarenal crystal in rats, we used low doses of an uricase inhibitor (2% oxonic acid). Hyperuricemia …
Hyperfiltration and diabetic nephropathy: is it the beginning? Or is it the end?
Castellino P, Shohat J, DeFronzo RA. Castellino P, et al. Semin Nephrol. 1990 May;10(3):228-41. Semin Nephrol. 1990. PMID: 2190280 Review.
The potential mechanisms by which glomerular hypertrophy can lead to renal histologic damage were discussed previously. By increasing the luminal diameter, glomerular hypertrophy also would be expected to augment wall tension and thereby increase intra …
The potential mechanisms by which glomerular hypertrophy can lead to renal histologic damage were discussed previously. By inc …
The key role of the transforming growth factor-beta system in the pathogenesis of diabetic nephropathy.
Chen S, Hong SW, Iglesias-de la Cruz MC, Isono M, Casaretto A, Ziyadeh FN. Chen S, et al. Ren Fail. 2001 May-Jul;23(3-4):471-81. doi: 10.1081/jdi-100104730. Ren Fail. 2001. PMID: 11499562 Review.
We demonstrate that short-term treatment of diabetic mice with neutralizing monoclonal antibodies against TGF-beta significantly reduces kidney weight and glomerular hypertrophy and attenuates the increase in extracellular matrix mRNAs. ...
We demonstrate that short-term treatment of diabetic mice with neutralizing monoclonal antibodies against TGF-beta significantly reduces kid …
AGE/RAGE signaling-mediated endoplasmic reticulum stress and future prospects in non-coding RNA therapeutics for diabetic nephropathy.
Pathomthongtaweechai N, Chutipongtanate S. Pathomthongtaweechai N, et al. Biomed Pharmacother. 2020 Nov;131:110655. doi: 10.1016/j.biopha.2020.110655. Epub 2020 Aug 24. Biomed Pharmacother. 2020. PMID: 32853909 Free article. Review.
Activation of receptor for AGEs (RAGE) stimulates NADPH oxidase-mediated reactive oxygen species (ROS) production, leading to ER stress, inflammation, glomerular hypertrophy, podocyte injury, and renal fibrosis. A growing body of evidence indicates that non-coding R …
Activation of receptor for AGEs (RAGE) stimulates NADPH oxidase-mediated reactive oxygen species (ROS) production, leading to ER stress, inf …
Oxidative stress in diabetic nephropathy.
Kashihara N, Haruna Y, Kondeti VK, Kanwar YS. Kashihara N, et al. Curr Med Chem. 2010;17(34):4256-69. doi: 10.2174/092986710793348581. Curr Med Chem. 2010. PMID: 20939814 Free PMC article. Review.
Diabetic nephropathy is a leading cause of end-stage renal failure worldwide. Its morphologic characteristics include glomerular hypertrophy, basement membrane thickening, mesangial expansion, tubular atrophy, interstitial fibrosis and arteriolar thickening. ...
Diabetic nephropathy is a leading cause of end-stage renal failure worldwide. Its morphologic characteristics include glomerular h …
Kidney Hyperfiltration After Nephrectomy: A Mechanism to Restore Kidney Function in Living Donors.
Marbun MB, Susalit E. Marbun MB, et al. Acta Med Indones. 2020 Oct;52(4):413-419. Acta Med Indones. 2020. PMID: 33377886 Free article. Review.
Hyperfiltration is caused by increased in kidney blood flow and glomerular hypertrophy. Both conditions are regulated by various factors. ...
Hyperfiltration is caused by increased in kidney blood flow and glomerular hypertrophy. Both conditions are regulated by vario …
73 results