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Year Number of Results
1991 1
1994 1
2003 1
2005 1
2008 3
2009 2
2010 1
2011 4
2012 3
2013 5
2014 9
2015 5
2016 5
2017 2
2018 3
2019 2
2020 5
2022 1
2023 6
2024 3

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58 results

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Page 1
Photodynamic therapy for basal cell carcinoma.
Fargnoli MC, Peris K. Fargnoli MC, et al. Future Oncol. 2015 Nov;11(22):2991-6. doi: 10.2217/fon.15.208. Epub 2015 Nov 9. Future Oncol. 2015. PMID: 26550910 Review.
Efficacy of photodynamic therapy in basal cell carcinoma is supported by substantial research and clinical trials. In this article, we review the procedure, indications and clinical evidences for the use of photodynamic therapy in the treatment of basal cell carcino …
Efficacy of photodynamic therapy in basal cell carcinoma is supported by substantial research and clinical trials. In this article, w …
Cancer interception.
Blackburn EH. Blackburn EH. Cancer Prev Res (Phila). 2011 Jun;4(6):787-92. doi: 10.1158/1940-6207.CAPR-11-0195. Cancer Prev Res (Phila). 2011. PMID: 21636545
For example, hedgehog pathway studies of mutations in the patched homolog 1 (PTCH1) gene, which constitutively activates Smoothened (SMO), led to development of an oral SMO inhibitor active in advanced basal cell carcinoma and which, in very high-risk Gorlin syndrome …
For example, hedgehog pathway studies of mutations in the patched homolog 1 (PTCH1) gene, which constitutively activates Smoothened (SMO), l …
SHH inhibitors for the treatment of medulloblastoma.
Samkari A, White J, Packer R. Samkari A, et al. Expert Rev Neurother. 2015;15(7):763-70. doi: 10.1586/14737175.2015.1052796. Epub 2015 May 31. Expert Rev Neurother. 2015. PMID: 26027634 Review.
The SHH group is characterized by constitutive activation of the SHH signaling pathway, and genetically characterized by mutations in patched homolog 1 (PTCH1) or other downstream pathway mutations. SHH inhibitors have become of great clinical interest in treating SHH-driv …
The SHH group is characterized by constitutive activation of the SHH signaling pathway, and genetically characterized by mutations in patche …
Vismodegib: A Review in Advanced Basal Cell Carcinoma.
Frampton JE, Basset-Séguin N. Frampton JE, et al. Drugs. 2018 Jul;78(11):1145-1156. doi: 10.1007/s40265-018-0948-9. Drugs. 2018. PMID: 30030732 Review.
The full European approval of vismodegib was based on the results of two phase II, open-label, noncomparative, international trials (ERIVANCE BCC and STEVIE), both of which showed high rates of tumour control in the indicated patient populations, including individuals with or wit …
The full European approval of vismodegib was based on the results of two phase II, open-label, noncomparative, international trials (ERIVANC …
Clinical implications of hedgehog signaling pathway inhibitors.
Liu H, Gu D, Xie J. Liu H, et al. Chin J Cancer. 2011 Jan;30(1):13-26. doi: 10.5732/cjc.010.10540. Chin J Cancer. 2011. PMID: 21192841 Free PMC article. Review.
The first link of Hh signaling to cancer was established through studies of a rare familial disease, Gorlin syndrome, in 1996. Follow-up studies revealed activation of this pathway in basal cell carcinoma, medulloblastoma and, leukemia as well as in gastrointestinal …
The first link of Hh signaling to cancer was established through studies of a rare familial disease, Gorlin syndrome, in 1996. …
Targeted therapy for hereditary cancer syndromes: neurofibromatosis type 1, neurofibromatosis type 2, and Gorlin syndrome.
Agarwal R, Liebe S, Turski ML, Vidwans SJ, Janku F, Garrido-Laguna I, Munoz J, Schwab R, Rodon J, Kurzrock R, Subbiah V; Pan-Cancer Working Group. Agarwal R, et al. Discov Med. 2014 Dec;18(101):323-30. Discov Med. 2014. PMID: 25549703 Free article. Review.
In this review, we seek to characterize some of the involved aberrations and associated targeted therapies for several germline malignancies, including neurofibromatosis types 1 and 2, and Gorlin syndrome. Though patients with hereditary cancer syndromes may be too …
In this review, we seek to characterize some of the involved aberrations and associated targeted therapies for several germline malignancies …
Photodynamic Therapy in Treating a Subset of Basal Cell Carcinoma: Strengths, Shortcomings, Comparisons with Surgical Modalities, and Potential Role as Adjunctive Therapy.
Chen M, Zhou A, Khachemoune A. Chen M, et al. Am J Clin Dermatol. 2024 Jan;25(1):99-118. doi: 10.1007/s40257-023-00829-w. Epub 2023 Dec 2. Am J Clin Dermatol. 2024. PMID: 38042767 Review.
In particular, PDT may be considered an adjuvant for the prevention and treatment of BCC lesions in patients with some genetic syndromes such as Gorlin syndrome, and in combination with surgical excision in lesions presenting in certain locations. ...
In particular, PDT may be considered an adjuvant for the prevention and treatment of BCC lesions in patients with some genetic syndromes suc …
Meier-Gorlin syndrome: growth and secondary sexual development of a microcephalic primordial dwarfism disorder.
de Munnik SA, Otten BJ, Schoots J, Bicknell LS, Aftimos S, Al-Aama JY, van Bever Y, Bober MB, Borm GF, Clayton-Smith J, Deal CL, Edrees AY, Feingold M, Fryer A, van Hagen JM, Hennekam RC, Jansweijer MC, Johnson D, Kant SG, Opitz JM, Ramadevi AR, Reardon W, Ross A, Sarda P, Schrander-Stumpel CT, Sluiter AE, Temple IK, Terhal PA, Toutain A, Wise CA, Wright M, Skidmore DL, Samuels ME, Hoefsloot LH, Knoers NV, Brunner HG, Jackson AP, Bongers EM. de Munnik SA, et al. Am J Med Genet A. 2012 Nov;158A(11):2733-42. doi: 10.1002/ajmg.a.35681. Epub 2012 Sep 28. Am J Med Genet A. 2012. PMID: 23023959
Meier-Gorlin syndrome (MGS) is a rare autosomal recessive disorder characterized by primordial dwarfism, microtia, and patellar aplasia/hypoplasia. ...
Meier-Gorlin syndrome (MGS) is a rare autosomal recessive disorder characterized by primordial dwarfism, microtia, and patella …
Systemic treatments for basal cell carcinoma (BCC): the advent of dermato-oncology in BCC.
Ali FR, Lear JT. Ali FR, et al. Br J Dermatol. 2013 Jul;169(1):53-7. doi: 10.1111/bjd.12311. Br J Dermatol. 2013. PMID: 23488543 Review.
Phase 2 trials have demonstrated efficacy in cases of locally advanced and metastatic BCC, as well as cases of hereditary basal cell naevus (Gorlin) syndrome. Side-effects are frequent and considerable and include myalgia, taste disturbance, alopecia, weight loss an …
Phase 2 trials have demonstrated efficacy in cases of locally advanced and metastatic BCC, as well as cases of hereditary basal cell naevus …
58 results