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Quoted phrase not found in phrase index: "Grade 1 Clear Cell Renal Cell Carcinoma"
Page 1
Grading of renal cell carcinoma.
Delahunt B, Eble JN, Egevad L, Samaratunga H. Delahunt B, et al. Histopathology. 2019 Jan;74(1):4-17. doi: 10.1111/his.13735. Histopathology. 2019. PMID: 30565310 Review.
Grading of renal cell carcinoma (RCC) has been recognised as a prognostic factor for almost 100 years. ...This grading system has been validated for both clear cell and papillary RCC. ...
Grading of renal cell carcinoma (RCC) has been recognised as a prognostic factor for almost 100 years. ...This
Phase II Trial of Cabozantinib Plus Nivolumab in Patients With Non-Clear-Cell Renal Cell Carcinoma and Genomic Correlates.
Lee CH, Voss MH, Carlo MI, Chen YB, Zucker M, Knezevic A, Lefkowitz RA, Shapnik N, Dadoun C, Reznik E, Shah NJ, Owens CN, McHugh DJ, Aggen DH, Laccetti AL, Kotecha R, Feldman DR, Motzer RJ. Lee CH, et al. J Clin Oncol. 2022 Jul 20;40(21):2333-2341. doi: 10.1200/JCO.21.01944. Epub 2022 Mar 17. J Clin Oncol. 2022. PMID: 35298296 Free PMC article. Clinical Trial.
PURPOSE: To assess the efficacy and safety of cabozantinib plus nivolumab in a phase II trial in patients with non-clear-cell renal cell carcinoma (RCC). PATIENTS AND METHODS: Patients had advanced non-clear-cell renal ca
PURPOSE: To assess the efficacy and safety of cabozantinib plus nivolumab in a phase II trial in patients with non-clear-cell
Multimodal recurrence scoring system for prediction of clear cell renal cell carcinoma outcome: a discovery and validation study.
Gui CP, Chen YH, Zhao HW, Cao JZ, Liu TJ, Xiong SW, Yu YF, Liao B, Cao Y, Li JY, Huang KB, Han H, Zhang ZL, Chen WF, Jiang ZY, Gao Y, Han GP, Tang Q, Ouyang K, Qu GM, Wu JT, Guo JP, Li CX, Li PX, Liu ZP, Hsieh JT, Cai MY, Li XS, Wei JH, Luo JH. Gui CP, et al. Lancet Digit Health. 2023 Aug;5(8):e515-e524. doi: 10.1016/S2589-7500(23)00095-X. Epub 2023 Jun 29. Lancet Digit Health. 2023. PMID: 37393162 Free article.
BACKGROUND: Improved markers for predicting recurrence are needed to stratify patients with localised (stage I-III) renal cell carcinoma after surgery for selection of adjuvant therapy. ...INTERPRETATION: Our multimodal recurrence score is a pra …
BACKGROUND: Improved markers for predicting recurrence are needed to stratify patients with localised (stage I-III) renal c
Machine learning-based pathomics signature could act as a novel prognostic marker for patients with clear cell renal cell carcinoma.
Chen S, Jiang L, Gao F, Zhang E, Wang T, Zhang N, Wang X, Zheng J. Chen S, et al. Br J Cancer. 2022 Mar;126(5):771-777. doi: 10.1038/s41416-021-01640-2. Epub 2021 Nov 25. Br J Cancer. 2022. PMID: 34824449 Free PMC article.
BACKGROUND: Traditional histopathology performed by pathologists through naked eyes is insufficient for accurate survival prediction of clear cell renal cell carcinoma (ccRCC). METHODS: A total of 483 whole slide images (WSIs) data from t …
BACKGROUND: Traditional histopathology performed by pathologists through naked eyes is insufficient for accurate survival prediction
Radiogenomic Associations Clear Cell Renal Cell Carcinoma: An Exploratory Study.
Liu DH, Dani KA, Reddy SS, Lei X, Demirjian NL, Hwang DH, Varghese BA, Rhie SK, Yap FY, Quinn DI, Siddiqi I, Aron M, Vaishampayan U, Zahoor H, Cen SY, Gill IS, Duddalwar VA. Liu DH, et al. Oncology. 2023;101(6):375-388. doi: 10.1159/000530719. Epub 2023 Apr 20. Oncology. 2023. PMID: 37080171 Free article.
INTRODUCTION: This study investigates how quantitative texture analysis can be used to non-invasively identify novel radiogenomic correlations with clear cell renal cell carcinoma (ccRCC) biomarkers. METHODS: The Cancer Genome Atlas-Kidney Re
INTRODUCTION: This study investigates how quantitative texture analysis can be used to non-invasively identify novel radiogenomic correlatio …
Gleason and Fuhrman no longer make the grade.
Delahunt B, Egevad L, Samaratunga H, Martignoni G, Nacey JN, Srigley JR. Delahunt B, et al. Histopathology. 2016 Mar;68(4):475-81. doi: 10.1111/his.12803. Epub 2015 Nov 16. Histopathology. 2016. PMID: 26266664 Review.
In 2005 and 2014, the International Society of Urological Pathology (ISUP) proposed changes to Gleason scoring with the adoption of the ISUP grading for prostate cancer in 2014 (grade 1, score 3 + 3; grade 2, score 3 + 4; grade 3, …
In 2005 and 2014, the International Society of Urological Pathology (ISUP) proposed changes to Gleason scoring with the adoption of the ISUP …
A CT-based deep learning radiomics nomogram outperforms the existing prognostic models for outcome prediction in clear cell renal cell carcinoma: a multicenter study.
Nie P, Yang G, Wang Y, Xu Y, Yan L, Zhang M, Zhao L, Wang N, Zhao X, Li X, Cheng N, Wang Y, Chen C, Wang N, Duan S, Wang X, Wang Z. Nie P, et al. Eur Radiol. 2023 Dec;33(12):8858-8868. doi: 10.1007/s00330-023-09869-6. Epub 2023 Jun 30. Eur Radiol. 2023. PMID: 37389608
OBJECTIVES: To develop and validate a CT-based deep learning radiomics nomogram (DLRN) for outcome prediction in clear cell renal cell carcinoma (ccRCC), and its performance was compared with the Stage, Size, Grade, and Necrosis (S …
OBJECTIVES: To develop and validate a CT-based deep learning radiomics nomogram (DLRN) for outcome prediction in clear cell
Expression Of Bap1 In Clear Cell Renal Cell Carcinoma.
Fatima A, Mushtaq S, Loya A, Hassan U, Sheikh UN. Fatima A, et al. J Ayub Med Coll Abbottabad. 2022 Apr-Jun;34(2):283-287. doi: 10.55519/JAMC-02-9313. J Ayub Med Coll Abbottabad. 2022. PMID: 35576287 Free article.
BACKGROUND: BAP1 (BRCA1 associated protein 1 on chromosome 3) is a commonly mutated gene in clear cell renal cell carcinoma. ...Immunohistochemistry was used to evaluate the loss of nuclear expression of BAP1. RESULTS: Loss of BAP1 was …
BACKGROUND: BAP1 (BRCA1 associated protein 1 on chromosome 3) is a commonly mutated gene in clear cell renal
Multinucleated tumor cells in clear cell renal cell carcinoma.
Pacheco RR, Binboga Kurt B, Kosemehmetoglu K, Rothrock AT, Lightle A, Akgul M. Pacheco RR, et al. Am J Clin Pathol. 2023 Dec 1;160(6):603-611. doi: 10.1093/ajcp/aqad096. Am J Clin Pathol. 2023. PMID: 37555895

OBJECTIVES: Multinucleated tumor cells (MTCs) in clear cell renal cell carcinoma (ccRCC) are not well understood. ...Overall, MTCA was associated with an increased rate of recurrence (P = .004), higher metastatic potential (P < .001), and sho

OBJECTIVES: Multinucleated tumor cells (MTCs) in clear cell renal cell carcinoma (ccRCC) are not well und …
Cuproptosis related gene PDHB is identified as a biomarker inversely associated with the progression of clear cell renal cell carcinoma.
Wang H, Yang Z, He X, Guo F, Sun H, Xu S, Xu C, Wang Z, Wen H, Teng Z, Wang Y, Han Z. Wang H, et al. BMC Cancer. 2023 Aug 28;23(1):804. doi: 10.1186/s12885-023-11324-0. BMC Cancer. 2023. PMID: 37641032 Free PMC article.
Pyruvate dehydrogenase E1 subunit beta (PDHB) is one of the cuproptosis genesand is a nuclear-encoded pyruvate dehydrogenase, which catalyzes the conversion of pyruvate to acetyl coenzyme A. However, the mechanism of PDHB in clear cell renal cell ca
Pyruvate dehydrogenase E1 subunit beta (PDHB) is one of the cuproptosis genesand is a nuclear-encoded pyruvate dehydrogenase, which catalyze …
2,436 results