Rare Germline ATM Variants Influence the Development of Chronic Lymphocytic Leukemia.
Lampson BL, Gupta A, Tyekucheva S, Mashima K, Petráčková A, Wang Z, Wojciechowska N, Shaughnessy CJ, Baker PO, Fernandes SM, Shupe S, Machado JH, Fardoun R, Kim AS, Brown JR.
Lampson BL, et al.
J Clin Oncol. 2023 Feb 10;41(5):1116-1128. doi: 10.1200/JCO.22.00269. Epub 2022 Oct 31.
J Clin Oncol. 2023.
PMID: 36315919
Free PMC article.
RESULTS: Rare germline ATM variants are present in 24% of patients with CLL, significantly greater than that in patients with other lymphoid malignancies (16% prevalence), myeloid disease (15%), or no hematologic neoplasm (14%). Patients with CLL with germline ATM v …
RESULTS: Rare germline ATM variants are present in 24% of patients with CLL, significantly greater than that in patients with other lymphoid …