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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1947 1
1948 2
1949 2
1951 5
1952 13
1953 20
1954 23
1955 23
1956 20
1957 23
1958 43
1959 19
1962 3
1963 4
1964 14
1965 69
1966 144
1967 222
1968 294
1969 299
1970 308
1971 362
1972 441
1973 503
1974 587
1975 484
1976 448
1977 416
1978 385
1979 449
1980 423
1981 445
1982 444
1983 545
1984 606
1985 667
1986 701
1987 663
1988 711
1989 735
1990 809
1991 755
1992 813
1993 885
1994 1040
1995 1040
1996 1059
1997 1088
1998 1164
1999 1201
2000 1389
2001 1418
2002 1490
2003 1613
2004 1684
2005 1941
2006 2077
2007 2282
2008 2534
2009 2952
2010 2947
2011 3308
2012 3763
2013 4138
2014 4153
2015 4329
2016 4482
2017 4690
2018 4720
2019 4830
2020 4875
2021 4709
2022 4920
2023 4563
2024 1457

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91,120 results

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Page 1
Amyloid-related imaging abnormalities in amyloid-modifying therapeutic trials: recommendations from the Alzheimer's Association Research Roundtable Workgroup.
Sperling RA, Jack CR Jr, Black SE, Frosch MP, Greenberg SM, Hyman BT, Scheltens P, Carrillo MC, Thies W, Bednar MM, Black RS, Brashear HR, Grundman M, Siemers ER, Feldman HH, Schindler RJ. Sperling RA, et al. Alzheimers Dement. 2011 Jul;7(4):367-85. doi: 10.1016/j.jalz.2011.05.2351. Alzheimers Dement. 2011. PMID: 21784348 Free PMC article. Review.
Amyloid imaging related abnormalities (ARIA) have now been reported in clinical trials with multiple therapeutic avenues to lower amyloid-beta burden in Alzheimer's disease (AD). ...The workgroup proposes recommendations for the detection and monitoring of ARIA in ongoing …
Amyloid imaging related abnormalities (ARIA) have now been reported in clinical trials with multiple therapeutic avenues to lower amy …
Cerebral arterial spasm--a controlled trial of nimodipine in patients with subarachnoid hemorrhage.
Allen GS, Ahn HS, Preziosi TJ, Battye R, Boone SC, Boone SC, Chou SN, Kelly DL, Weir BK, Crabbe RA, Lavik PJ, Rosenbloom SB, Dorsey FC, Ingram CR, Mellits DE, Bertsch LA, Boisvert DP, Hundley MB, Johnson RK, Strom JA, Transou CR. Allen GS, et al. N Engl J Med. 1983 Mar 17;308(11):619-24. doi: 10.1056/NEJM198303173081103. N Engl J Med. 1983. PMID: 6338383 Clinical Trial.
We enrolled 125 neurologically normal patients with intracranial aneurysms in a multi-institution, prospective, double-blind, randomized, placebo-controlled trial within 96 hours of their subarachnoid hemorrhage, to determine whether treatment with the calciu …
We enrolled 125 neurologically normal patients with intracranial aneurysms in a multi-institution, prospective, double-blind, randomized …
Treatment Options in Hemophilia.
Miesbach W, Schwäble J, Müller MM, Seifried E. Miesbach W, et al. Dtsch Arztebl Int. 2019 Nov 22;116(47):791-798. doi: 10.3238/arztebl.2019.0791. Dtsch Arztebl Int. 2019. PMID: 31847949 Free PMC article. Review.
METHODS: This review is based on pertinent publications retrieved by a selective search in MEDLINE/PubMed, as well as on expert opinions and the recommenda- tions of specialty societies. RESULTS: Randomized controlled trials have shown that, in children aged 30 months to 6 …
METHODS: This review is based on pertinent publications retrieved by a selective search in MEDLINE/PubMed, as well as on expert opinions and …
Acute hypertensive response in patients with intracerebral hemorrhage pathophysiology and treatment.
Qureshi AI, Qureshi MH. Qureshi AI, et al. J Cereb Blood Flow Metab. 2018 Sep;38(9):1551-1563. doi: 10.1177/0271678X17725431. Epub 2017 Aug 16. J Cereb Blood Flow Metab. 2018. PMID: 28812942 Free PMC article. Review.
Therefore, intensive reduction of systolic blood pressure has been evaluated in several clinical trials as a strategy to reduce hematoma expansion and subsequent death and disability. These trials have demonstrated either a small magnitude benefit (second intensive blood p …
Therefore, intensive reduction of systolic blood pressure has been evaluated in several clinical trials as a strategy to reduce hemat …
Bridging Anticoagulation: Primum Non Nocere.
Rechenmacher SJ, Fang JC. Rechenmacher SJ, et al. J Am Coll Cardiol. 2015 Sep 22;66(12):1392-403. doi: 10.1016/j.jacc.2015.08.002. J Am Coll Cardiol. 2015. PMID: 26383727 Free article. Review.
Moreover, indications for anticoagulation interruption may be unclear. New observational studies and a recent large randomized trial have noted significant perioperative or periprocedural bleeding rates without reduction in thromboembolism when bridging is employed. …
Moreover, indications for anticoagulation interruption may be unclear. New observational studies and a recent large randomized tri …
Biases in reporting of adverse effects in clinical trials, and potential impact on safety assessments in systematic reviews and therapy guidelines.
Westergren T, Narum S, Klemp M. Westergren T, et al. Basic Clin Pharmacol Toxicol. 2022 Dec;131(6):465-473. doi: 10.1111/bcpt.13791. Epub 2022 Oct 5. Basic Clin Pharmacol Toxicol. 2022. PMID: 36125975 Free PMC article. Review.
Trial publication bias may have profound effects on safety perceptions. ...METHODS: We performed literature reviews and descriptive analyse of clinical trials with corticosteroids, and publications from the TADS trial. ...
Trial publication bias may have profound effects on safety perceptions. ...METHODS: We performed literature reviews and descriptive a …
Evaluation of hetastarch.
Nakasato SK. Nakasato SK. Clin Pharm. 1982 Nov-Dec;1(6):509-14. Clin Pharm. 1982. PMID: 6192962 Review.
The indications, pharmacology, adverse reactions, clinical studies, dosage, and cost of hetastarch are reviewed. Hetastarch is a plasma volume expander used in adults for the treatment of shock caused by hemorrhage, burns, surgery, sepsis, or other trauma. ...
The indications, pharmacology, adverse reactions, clinical studies, dosage, and cost of hetastarch are reviewed. Hetastarch is a plas …
Thrombolysis for non-traumatic intra-ventricular hemorrhage in adults: a critical reappraisal.
Starnoni D, Oddo M, Maduri R, Messerer M, Daniel RT. Starnoni D, et al. Minerva Anestesiol. 2017 Sep;83(9):982-993. doi: 10.23736/S0375-9393.17.12073-0. Epub 2017 Jun 12. Minerva Anestesiol. 2017. PMID: 28607341 Free article. Review.
Intra-ventricular hemorrhage (IVH) is a critical condition with high rate of morbidity and mortality due to acute hydrocephalus and secondary brain injury. ...Its effectiveness on functional outcome has been assessed on three large meta-analysis and a recent large rando …
Intra-ventricular hemorrhage (IVH) is a critical condition with high rate of morbidity and mortality due to acute hydrocephalus and s …
Neuroprotective strategies for intracerebral hemorrhage: trials and translation.
Kellner CP, Connolly ES Jr. Kellner CP, et al. Stroke. 2010 Oct;41(10 Suppl):S99-102. doi: 10.1161/STROKEAHA.110.597476. Stroke. 2010. PMID: 20876519 Review.
Although each of these trials failed to show a benefit, animal research continues to supply the translational pipeline and 5 clinical trials evaluating neuroprotective agents in intracerebral hemorrhage are currently ongoing. Despite initial failures, neuroprotectiv …
Although each of these trials failed to show a benefit, animal research continues to supply the translational pipeline and 5 clinical …
Data Standardization and Quality Management.
Lapchak PA, Zhang JH. Lapchak PA, et al. Transl Stroke Res. 2018 Feb;9(1):4-8. doi: 10.1007/s12975-017-0531-9. Epub 2017 Mar 10. Transl Stroke Res. 2018. PMID: 28283966
Thus, herein, we propose steps to prepare research study data in an acceptable form for archival purposes so that standards for translational research data can be comparable to those that are accepted and adhered to by the clinical community. If all translational research …
Thus, herein, we propose steps to prepare research study data in an acceptable form for archival purposes so that standards for translationa …
91,120 results
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